MXPA02006212A - Inhibidores de fosfodiesterasa amp-especifica ciclica. - Google Patents
Inhibidores de fosfodiesterasa amp-especifica ciclica.Info
- Publication number
- MXPA02006212A MXPA02006212A MXPA02006212A MXPA02006212A MXPA02006212A MX PA02006212 A MXPA02006212 A MX PA02006212A MX PA02006212 A MXPA02006212 A MX PA02006212A MX PA02006212 A MXPA02006212 A MX PA02006212A MX PA02006212 A MXPA02006212 A MX PA02006212A
- Authority
- MX
- Mexico
- Prior art keywords
- ampspecific
- cyclic
- phosphodiesterase inhibitors
- pyrrolidine derivatives
- disclosed
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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Abstract
Se exponen compuestos novedosos de pirrolidina que son inhibidores potentes y selectivos de la PDE4, asi como tambien los metodos para producir los mismos. Tambien se expone el uso de los compuestos en el tratamiento de enfermedades inflamatorias y otras enfermedades que incluyen niveles elevados de citocinas, asi como tambien trastornos del sistema nervioso central (CNS).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/471,846 US6258833B1 (en) | 1999-12-23 | 1999-12-23 | Cyclic AMP-specific phosphodiesterase inhibitors |
PCT/US2000/032401 WO2001047905A1 (en) | 1999-12-23 | 2000-11-28 | Pyrrolidine derivatives as cyclic amp-specific phosphodiesterase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02006212A true MXPA02006212A (es) | 2004-02-26 |
Family
ID=23873210
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02006212A MXPA02006212A (es) | 1999-12-23 | 2000-11-28 | Inhibidores de fosfodiesterasa amp-especifica ciclica. |
Country Status (29)
Country | Link |
---|---|
US (6) | US6258833B1 (es) |
EP (1) | EP1242400B1 (es) |
JP (1) | JP4294903B2 (es) |
KR (1) | KR20020063600A (es) |
CN (1) | CN1434813A (es) |
AT (1) | ATE325108T1 (es) |
AU (1) | AU778543B2 (es) |
BG (1) | BG65892B1 (es) |
BR (1) | BRPI0016693B1 (es) |
CA (1) | CA2395193C (es) |
CZ (1) | CZ20022188A3 (es) |
DE (1) | DE60027769D1 (es) |
EA (1) | EA005686B1 (es) |
EE (1) | EE05087B1 (es) |
GE (1) | GEP20043384B (es) |
HK (1) | HK1051359A1 (es) |
HR (1) | HRP20020541B1 (es) |
HU (1) | HUP0301113A3 (es) |
IL (1) | IL150313A0 (es) |
IS (1) | IS6436A (es) |
MX (1) | MXPA02006212A (es) |
NO (1) | NO20023008L (es) |
PL (1) | PL202227B1 (es) |
RS (1) | RS50841B (es) |
SK (1) | SK287964B6 (es) |
TR (1) | TR200400702T4 (es) |
UA (1) | UA73964C2 (es) |
WO (1) | WO2001047905A1 (es) |
ZA (1) | ZA200205551B (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6455571B1 (en) * | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
US6258833B1 (en) * | 1999-12-23 | 2001-07-10 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
US20030022814A1 (en) * | 2000-02-29 | 2003-01-30 | Reines Scott A | Method for treating or preventing depression |
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