MXPA02004710A

MXPA02004710A - Compuestos aza que tienen actividad neuronal.

Compuestos aza que tienen actividad neuronal.

Info

Publication number: MXPA02004710A
Authority: MX; Mexico
Prior art keywords: compound; further characterized; substituents; heteroaryl; alkyl
Prior art date: 1999-11-12

Application number

MXPA02004710A

Other languages

English (en)

Spanish (es)

Inventor

S Hamilton Gregory

Original Assignee

Guilford Pharm Inc

Priority date

1999-11-12

Filing date

2000-08-28

Publication date

2002-09-02

2000-08-28 Application filed by Guilford Pharm Inc filed Critical Guilford Pharm Inc

2002-09-02 Publication of MXPA02004710A publication Critical patent/MXPA02004710A/es

Links

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150000001875 compounds Chemical class 0.000 claims abstract description 146
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 22
-1 4-Phenylbutyl Chemical group 0.000 claims description 78
125000001424 substituent group Chemical group 0.000 claims description 46
125000003118 aryl group Chemical group 0.000 claims description 43
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 39
125000000623 heterocyclic group Chemical group 0.000 claims description 39
125000001072 heteroaryl group Chemical group 0.000 claims description 37
150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 32
125000003342 alkenyl group Chemical group 0.000 claims description 31
150000003839 salts Chemical class 0.000 claims description 30
230000000694 effects Effects 0.000 claims description 27
125000000217 alkyl group Chemical group 0.000 claims description 25
150000002148 esters Chemical class 0.000 claims description 25
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201000010099 disease Diseases 0.000 claims description 21
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239000012453 solvate Substances 0.000 claims description 21
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239000003102 growth factor Substances 0.000 claims description 18
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238000011282 treatment Methods 0.000 claims description 18
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