MX9800212A - Fenilacetil-coa ligasa a partir de penicillium chrysogenum. - Google Patents

Fenilacetil-coa ligasa a partir de penicillium chrysogenum.

Info

Publication number
MX9800212A
MX9800212A MX9800212A MX9800212A MX9800212A MX 9800212 A MX9800212 A MX 9800212A MX 9800212 A MX9800212 A MX 9800212A MX 9800212 A MX9800212 A MX 9800212A MX 9800212 A MX9800212 A MX 9800212A
Authority
MX
Mexico
Prior art keywords
phenylacetyl
penicillium chrysogenum
coa ligase
enzyme
chrysogenum
Prior art date
Application number
MX9800212A
Other languages
English (en)
Other versions
MXPA98000212A (es
Inventor
Linden Gledhill
Philip Andrew Greaves
John Patrick Griffin
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MXPA98000212A publication Critical patent/MXPA98000212A/es
Publication of MX9800212A publication Critical patent/MX9800212A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/02—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin in presence of phenylacetic acid or phenylacetamide or their derivatives not to be used

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Un procedimiento para preparar una enzima a partir de Penicillium chrysogenum que tiene actividad de fenilacetato-Coenzima A; también se provee codificacion de ADN para la enzima y su uso en la produccion de cepas modificadas.
MX9800212A 1995-06-30 1996-06-26 Fenilacetil-coa ligasa a partir de penicillium chrysogenum. MX9800212A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9513403.7 1995-06-30
GBGB9513403.7A GB9513403D0 (en) 1995-06-30 1995-06-30 Novel product
PCT/EP1996/002799 WO1997002349A1 (en) 1995-06-30 1996-06-26 PHENYLACETYL-CoA LIGASE FROM PENICILLIUM CHRYSOGENUM

Publications (2)

Publication Number Publication Date
MXPA98000212A MXPA98000212A (es) 1998-04-01
MX9800212A true MX9800212A (es) 1998-04-30

Family

ID=10776961

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9800212A MX9800212A (es) 1995-06-30 1996-06-26 Fenilacetil-coa ligasa a partir de penicillium chrysogenum.

Country Status (17)

Country Link
US (1) US6245524B1 (es)
EP (1) EP0835316B1 (es)
JP (1) JP3819429B2 (es)
KR (1) KR100455054B1 (es)
CN (1) CN1145699C (es)
AT (1) ATE239081T1 (es)
AU (1) AU6417396A (es)
DE (1) DE69627856T2 (es)
DK (1) DK0835316T3 (es)
ES (1) ES2198493T3 (es)
GB (1) GB9513403D0 (es)
HK (1) HK1010213A1 (es)
MX (1) MX9800212A (es)
PL (2) PL188190B1 (es)
PT (1) PT835316E (es)
SI (1) SI0835316T1 (es)
WO (1) WO1997002349A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69534041T2 (de) * 1994-09-28 2006-04-13 Dsm Ip Assets B.V. Verfahren zur herstellung von beta lactam antibiotika durch mikroorganismen mit erhoehter ligaseaktivitaet
ES2108651B1 (es) 1996-03-18 1998-07-16 Antibioticos Sa Procedimiento para incrementar la produccion de penicilina g (bencilpenicilina) en penicillium chrysogenum mediante la expresion del gen pcl.
ES2220176B1 (es) * 2002-05-27 2006-02-16 Universidad De Extremadura Nuevo enzima protelotico, procedimiento para su obtencion y aplicaciones.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69534041T2 (de) 1994-09-28 2006-04-13 Dsm Ip Assets B.V. Verfahren zur herstellung von beta lactam antibiotika durch mikroorganismen mit erhoehter ligaseaktivitaet

Also Published As

Publication number Publication date
CN1145699C (zh) 2004-04-14
PL186765B1 (pl) 2004-02-27
KR19990028533A (ko) 1999-04-15
PT835316E (pt) 2003-08-29
HK1010213A1 (en) 1999-06-17
GB9513403D0 (en) 1995-09-06
US6245524B1 (en) 2001-06-12
KR100455054B1 (ko) 2005-01-17
DK0835316T3 (da) 2003-08-25
EP0835316A1 (en) 1998-04-15
DE69627856T2 (de) 2004-03-11
ES2198493T3 (es) 2004-02-01
EP0835316B1 (en) 2003-05-02
JPH11508450A (ja) 1999-07-27
DE69627856D1 (de) 2003-06-05
CN1194002A (zh) 1998-09-23
PL188190B1 (pl) 2004-12-31
PL324225A1 (en) 1998-05-11
AU6417396A (en) 1997-02-05
ATE239081T1 (de) 2003-05-15
JP3819429B2 (ja) 2006-09-06
WO1997002349A1 (en) 1997-01-23
SI0835316T1 (en) 2003-12-31

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees