MX9705737A - Indanilidinacetilguanidinas sustituidas, procedimiento para su preparacion, su uso como medicamentos o agentes de diagnostico y medicamentos que las contienen. - Google Patents
Indanilidinacetilguanidinas sustituidas, procedimiento para su preparacion, su uso como medicamentos o agentes de diagnostico y medicamentos que las contienen.Info
- Publication number
- MX9705737A MX9705737A MX9705737A MX9705737A MX9705737A MX 9705737 A MX9705737 A MX 9705737A MX 9705737 A MX9705737 A MX 9705737A MX 9705737 A MX9705737 A MX 9705737A MX 9705737 A MX9705737 A MX 9705737A
- Authority
- MX
- Mexico
- Prior art keywords
- medicaments
- indanylidineacetylguanidines
- preparation
- substituted
- diagnosis agents
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 208000007530 Essential hypertension Diseases 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C327/54—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96112275A EP0837055A1 (en) | 1996-07-30 | 1996-07-30 | Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them |
| EP96112275 | 1996-07-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA97005737A MXPA97005737A (en) | 1998-02-01 |
| MX9705737A true MX9705737A (es) | 1998-02-28 |
Family
ID=8223055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9705737A MX9705737A (es) | 1996-07-30 | 1997-07-29 | Indanilidinacetilguanidinas sustituidas, procedimiento para su preparacion, su uso como medicamentos o agentes de diagnostico y medicamentos que las contienen. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5900436A (enExample) |
| EP (2) | EP0837055A1 (enExample) |
| JP (1) | JP4039589B2 (enExample) |
| KR (1) | KR980009236A (enExample) |
| CN (1) | CN1064351C (enExample) |
| AR (1) | AR008095A1 (enExample) |
| AT (1) | ATE207888T1 (enExample) |
| AU (1) | AU715187B2 (enExample) |
| BR (1) | BR9704131A (enExample) |
| CA (1) | CA2211982C (enExample) |
| CZ (1) | CZ241197A3 (enExample) |
| DE (1) | DE69707777T2 (enExample) |
| DK (1) | DK0822182T3 (enExample) |
| ES (1) | ES2164283T3 (enExample) |
| HR (1) | HRP970424B1 (enExample) |
| HU (1) | HUP9701316A3 (enExample) |
| ID (1) | ID17565A (enExample) |
| IL (1) | IL121407A0 (enExample) |
| MX (1) | MX9705737A (enExample) |
| NO (1) | NO308213B1 (enExample) |
| NZ (1) | NZ328440A (enExample) |
| PL (1) | PL321392A1 (enExample) |
| PT (1) | PT822182E (enExample) |
| RU (1) | RU2176638C2 (enExample) |
| SI (1) | SI0822182T1 (enExample) |
| SK (1) | SK282128B6 (enExample) |
| TR (1) | TR199700704A2 (enExample) |
| TW (1) | TW445251B (enExample) |
| ZA (1) | ZA976735B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| CN103819403B (zh) | 2008-12-31 | 2017-01-04 | 阿德利克斯公司 | 用于治疗与体液潴留或盐超负荷有关的病症和胃肠道病症的化合物和方法 |
| GB0916163D0 (en) * | 2009-09-15 | 2009-10-28 | Shire Llc | Prodrugs of guanfacine |
| CN105392483B (zh) | 2013-04-12 | 2019-03-15 | 阿德利克斯公司 | 用于抑制磷酸盐转运的nhe3结合化合物和方法 |
| EA201991676A1 (ru) | 2017-01-09 | 2020-01-30 | Арделикс, Инк. | Ингибиторы nhe-опосредованного антипорта |
| KR20240090875A (ko) | 2017-01-09 | 2024-06-21 | 알데릭스, 인코포레이티드 | 위장관 장애를 치료하는 데 유용한 화합물 |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
| CN116492469A (zh) * | 2023-05-22 | 2023-07-28 | 遵义医科大学附属医院 | 一种通道阻滞剂在制备治疗和/或预防肝纤维疾病药物中的应用 |
| CN119118881B (zh) * | 2024-07-25 | 2026-01-02 | 中国农业大学 | 含胍基的5-氯茚满化合物及其制备方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| DE4421536A1 (de) * | 1994-06-20 | 1995-12-21 | Hoechst Ag | Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| ES2135811T3 (es) * | 1995-04-18 | 1999-11-01 | Hoechst Ag | Indenoil-guanidinas sustituidas antiarritmicas y cardioprotectoras. |
-
1996
- 1996-07-30 EP EP96112275A patent/EP0837055A1/en not_active Withdrawn
-
1997
- 1997-05-23 TW TW086106928A patent/TW445251B/zh active
- 1997-07-14 ID IDP972422A patent/ID17565A/id unknown
- 1997-07-24 EP EP97112674A patent/EP0822182B1/en not_active Expired - Lifetime
- 1997-07-24 PT PT97112674T patent/PT822182E/pt unknown
- 1997-07-24 AT AT97112674T patent/ATE207888T1/de not_active IP Right Cessation
- 1997-07-24 ES ES97112674T patent/ES2164283T3/es not_active Expired - Lifetime
- 1997-07-24 SI SI9730260T patent/SI0822182T1/xx unknown
- 1997-07-24 DE DE69707777T patent/DE69707777T2/de not_active Expired - Lifetime
- 1997-07-24 DK DK97112674T patent/DK0822182T3/da active
- 1997-07-28 US US08/901,099 patent/US5900436A/en not_active Expired - Lifetime
- 1997-07-28 KR KR1019970035527A patent/KR980009236A/ko not_active Ceased
- 1997-07-28 AR ARP970103414A patent/AR008095A1/es unknown
- 1997-07-28 CZ CZ972411A patent/CZ241197A3/cs unknown
- 1997-07-28 IL IL12140797A patent/IL121407A0/xx unknown
- 1997-07-28 AU AU31554/97A patent/AU715187B2/en not_active Ceased
- 1997-07-28 NZ NZ328440A patent/NZ328440A/en unknown
- 1997-07-28 CN CN97114777A patent/CN1064351C/zh not_active Expired - Fee Related
- 1997-07-28 TR TR97/00704A patent/TR199700704A2/xx unknown
- 1997-07-28 SK SK1034-97A patent/SK282128B6/sk unknown
- 1997-07-29 PL PL97321392A patent/PL321392A1/xx unknown
- 1997-07-29 NO NO973486A patent/NO308213B1/no not_active IP Right Cessation
- 1997-07-29 CA CA002211982A patent/CA2211982C/en not_active Expired - Fee Related
- 1997-07-29 MX MX9705737A patent/MX9705737A/es not_active IP Right Cessation
- 1997-07-29 HR HR970424A patent/HRP970424B1/xx not_active IP Right Cessation
- 1997-07-29 HU HU9701316A patent/HUP9701316A3/hu unknown
- 1997-07-29 JP JP20275697A patent/JP4039589B2/ja not_active Expired - Fee Related
- 1997-07-29 RU RU97113146/04A patent/RU2176638C2/ru not_active IP Right Cessation
- 1997-07-29 ZA ZA9706735A patent/ZA976735B/xx unknown
- 1997-07-29 BR BR9704131A patent/BR9704131A/pt active Search and Examination
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |