HRP970424B1 - Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them - Google Patents
Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing themInfo
- Publication number
- HRP970424B1 HRP970424B1 HR970424A HRP970424A HRP970424B1 HR P970424 B1 HRP970424 B1 HR P970424B1 HR 970424 A HR970424 A HR 970424A HR P970424 A HRP970424 A HR P970424A HR P970424 B1 HRP970424 B1 HR P970424B1
- Authority
- HR
- Croatia
- Prior art keywords
- medicaments
- indanylidineacetylguanidines
- substituted
- preparation
- diagnostic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C327/54—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96112275A EP0837055A1 (en) | 1996-07-30 | 1996-07-30 | Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP970424A2 HRP970424A2 (en) | 1998-06-30 |
HRP970424B1 true HRP970424B1 (en) | 2002-06-30 |
Family
ID=8223055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR970424A HRP970424B1 (en) | 1996-07-30 | 1997-07-29 | Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them |
Country Status (29)
Country | Link |
---|---|
US (1) | US5900436A (xx) |
EP (2) | EP0837055A1 (xx) |
JP (1) | JP4039589B2 (xx) |
KR (1) | KR980009236A (xx) |
CN (1) | CN1064351C (xx) |
AR (1) | AR008095A1 (xx) |
AT (1) | ATE207888T1 (xx) |
AU (1) | AU715187B2 (xx) |
BR (1) | BR9704131A (xx) |
CA (1) | CA2211982C (xx) |
CZ (1) | CZ241197A3 (xx) |
DE (1) | DE69707777T2 (xx) |
DK (1) | DK0822182T3 (xx) |
ES (1) | ES2164283T3 (xx) |
HR (1) | HRP970424B1 (xx) |
HU (1) | HUP9701316A3 (xx) |
ID (1) | ID17565A (xx) |
IL (1) | IL121407A0 (xx) |
MX (1) | MX9705737A (xx) |
NO (1) | NO308213B1 (xx) |
NZ (1) | NZ328440A (xx) |
PL (1) | PL321392A1 (xx) |
PT (1) | PT822182E (xx) |
RU (1) | RU2176638C2 (xx) |
SI (1) | SI0822182T1 (xx) |
SK (1) | SK282128B6 (xx) |
TR (1) | TR199700704A2 (xx) |
TW (1) | TW445251B (xx) |
ZA (1) | ZA976735B (xx) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
BRPI0923861B8 (pt) | 2008-12-31 | 2021-05-25 | Ardelyx Inc | compostos e composições farmacêuticas para inibir o antiporte nhe-mediado no tratamento de distúrbios associados com a retenção de fluido ou com a sobrecarga de sal e distúrbios do trato gastrointestinal |
GB0916163D0 (en) * | 2009-09-15 | 2009-10-28 | Shire Llc | Prodrugs of guanfacine |
JP6377132B2 (ja) | 2013-04-12 | 2018-08-22 | アーデリクス,インコーポレーテッド | Nhe3結合化合物およびリン酸輸送の阻害方法 |
UA126283C2 (uk) | 2017-01-09 | 2022-09-14 | Арделікс, Інк. | Сполуки, придатні для лікування розладів шлунково-кишкового тракту |
BR112019013963A2 (pt) | 2017-01-09 | 2020-04-28 | Ardelyx Inc | inibidores de antiporte mediado por nhe |
CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
DE4421536A1 (de) * | 1994-06-20 | 1995-12-21 | Hoechst Ag | Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-07-30 EP EP96112275A patent/EP0837055A1/en not_active Withdrawn
-
1997
- 1997-05-23 TW TW086106928A patent/TW445251B/zh active
- 1997-07-14 ID IDP972422A patent/ID17565A/id unknown
- 1997-07-24 DK DK97112674T patent/DK0822182T3/da active
- 1997-07-24 EP EP97112674A patent/EP0822182B1/en not_active Expired - Lifetime
- 1997-07-24 PT PT97112674T patent/PT822182E/pt unknown
- 1997-07-24 AT AT97112674T patent/ATE207888T1/de not_active IP Right Cessation
- 1997-07-24 SI SI9730260T patent/SI0822182T1/xx unknown
- 1997-07-24 ES ES97112674T patent/ES2164283T3/es not_active Expired - Lifetime
- 1997-07-24 DE DE69707777T patent/DE69707777T2/de not_active Expired - Lifetime
- 1997-07-28 IL IL12140797A patent/IL121407A0/xx unknown
- 1997-07-28 US US08/901,099 patent/US5900436A/en not_active Expired - Lifetime
- 1997-07-28 AU AU31554/97A patent/AU715187B2/en not_active Ceased
- 1997-07-28 SK SK1034-97A patent/SK282128B6/sk unknown
- 1997-07-28 KR KR1019970035527A patent/KR980009236A/ko not_active Application Discontinuation
- 1997-07-28 NZ NZ328440A patent/NZ328440A/en unknown
- 1997-07-28 TR TR97/00704A patent/TR199700704A2/xx unknown
- 1997-07-28 CN CN97114777A patent/CN1064351C/zh not_active Expired - Fee Related
- 1997-07-28 AR ARP970103414A patent/AR008095A1/es unknown
- 1997-07-28 CZ CZ972411A patent/CZ241197A3/cs unknown
- 1997-07-29 ZA ZA9706735A patent/ZA976735B/xx unknown
- 1997-07-29 MX MX9705737A patent/MX9705737A/es not_active IP Right Cessation
- 1997-07-29 JP JP20275697A patent/JP4039589B2/ja not_active Expired - Fee Related
- 1997-07-29 BR BR9704131A patent/BR9704131A/pt active Search and Examination
- 1997-07-29 RU RU97113146/04A patent/RU2176638C2/ru not_active IP Right Cessation
- 1997-07-29 NO NO973486A patent/NO308213B1/no not_active IP Right Cessation
- 1997-07-29 PL PL97321392A patent/PL321392A1/xx unknown
- 1997-07-29 HU HU9701316A patent/HUP9701316A3/hu unknown
- 1997-07-29 HR HR970424A patent/HRP970424B1/xx not_active IP Right Cessation
- 1997-07-29 CA CA002211982A patent/CA2211982C/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP970450B1 (en) | Phenyl-substituted alkenoylguanidides, process for their preparation, their use as drugs or diagnostic agents and drugs containing them | |
EP0771788A3 (de) | Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament | |
HUP9900974A3 (en) | Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them | |
HUP9700328A3 (en) | Heteroaryl-oxazolidinones, process for their preparation, pharmaceutical compositions containing the same, their use and intermediates | |
HK1040980A1 (zh) | 聯苯磺酰基氨基氰、其製備方法及其作為藥物的用途 | |
HRP970292B1 (en) | Substituted 2-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them | |
HRP980502B1 (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-oles, processes for their preparation and their use as medicaments | |
CY2220B1 (en) | Substituted benzenesulfonylureas and -thioureas process for their preparation their use as medicament or diagnostic agent as well as medicaments containing them | |
ZA968091B (en) | Substituted benzolyguanidines a process for their preparation their use as a medicament or diagnostic agent and medicament comprising them | |
AU2330095A (en) | Ortho-amino-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them | |
HUP9600665A2 (en) | Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation | |
HRP970424B1 (en) | Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them | |
HRP970304B1 (en) | Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them | |
GR3035811T3 (en) | Substituted 1-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them | |
HU9601976D0 (en) | 4-fluoralkyl benzoylguanidines, process for producing them, their use for producing pharmaceutical or diagnostic compositions, and pharmaceutical compositions containing these compounds | |
HRP970081B1 (en) | Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them | |
HU9501546D0 (en) | Sulphamide-derivatives, process for their preparation and their use as insecticides | |
GR3032293T3 (en) | Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them | |
HRP970293A2 (en) | Bis-ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them | |
ZA97770B (en) | Substituted diaryldicarboxylic acid diguanidides processes for their preparation their use as a medicament or diagnostic and medicament containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
B1PR | Patent granted | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20030613 Year of fee payment: 7 |
|
PBON | Lapse due to non-payment of renewal fee |
Effective date: 20040730 |