MX9303454A - Nuevo procedimiento para la preparacion de compuestos esteroides 20-ceto-21alfa hidroxi y compuestos intermedios obtenidos mediante el mismo. - Google Patents
Nuevo procedimiento para la preparacion de compuestos esteroides 20-ceto-21alfa hidroxi y compuestos intermedios obtenidos mediante el mismo.Info
- Publication number
- MX9303454A MX9303454A MX9303454A MX9303454A MX9303454A MX 9303454 A MX9303454 A MX 9303454A MX 9303454 A MX9303454 A MX 9303454A MX 9303454 A MX9303454 A MX 9303454A MX 9303454 A MX9303454 A MX 9303454A
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- 21alfa
- hidroxi
- ceto
- same
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- -1 STEROID COMPOUNDS Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001033 ether group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C07J33/007—Cyclic thioketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
El invento se refiere a un nuevo procedimiento de preparación de compuestos (I): (Ver Fórmula I); donde R1 es alquilo (1-3C), R2 es alquilo (1-12C) y R3 es alquilo (1-4C). A partir del derivado 17B-CN,17a-OR4 correspondiente, donde R4 es un resto éter fácilmente escindible, así como los compuestos intermedios. Los compuestos (I) son conocidos y están descritos en la patente europea n° 7823.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9207047A FR2692267B1 (fr) | 1992-06-11 | 1992-06-11 | Nouveau procédé de préparation de composés stéroïdes 20-céto 21alpha-hydroxy et intermédiaires. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9303454A true MX9303454A (es) | 1994-07-29 |
Family
ID=9430627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9303454A MX9303454A (es) | 1992-06-11 | 1993-06-09 | Nuevo procedimiento para la preparacion de compuestos esteroides 20-ceto-21alfa hidroxi y compuestos intermedios obtenidos mediante el mismo. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5399685A (es) |
EP (1) | EP0574317B1 (es) |
JP (1) | JP3231901B2 (es) |
AT (1) | ATE143971T1 (es) |
CA (1) | CA2098146C (es) |
DE (2) | DE69305241T2 (es) |
DK (1) | DK0574317T3 (es) |
ES (1) | ES2092785T3 (es) |
FR (1) | FR2692267B1 (es) |
GR (1) | GR3021337T3 (es) |
HU (3) | HU213673B (es) |
MX (1) | MX9303454A (es) |
NL (1) | NL300068I1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2692267B1 (fr) * | 1992-06-11 | 1995-05-19 | Roussel Uclaf | Nouveau procédé de préparation de composés stéroïdes 20-céto 21alpha-hydroxy et intermédiaires. |
FR2749012B1 (fr) * | 1996-05-22 | 1998-08-07 | Hoechst Marion Roussel Inc | Nouveaux steroides 1 ou 6-hydroxyles, leur procede de preparation, leur application a titre de medicament et les compositions pharmaceutiques les renfermant |
FR2801218B1 (fr) * | 1999-11-23 | 2001-12-28 | Hoechst Marion Roussel Inc | Compositions pharmaceutiques comprenant de la trimegestone, leurs procedes de preparation ainsi que le conditionnement primaire les renfermant |
TW200306196A (en) * | 2002-04-03 | 2003-11-16 | Wyeth Corp | Hormone replacement therapy |
TW200306846A (en) * | 2002-04-03 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200306851A (en) * | 2002-04-29 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200400040A (en) * | 2002-05-17 | 2004-01-01 | Wyeth Corp | Hormone replacement therapy |
ITMI20042001A1 (it) | 2004-10-21 | 2005-01-21 | Ind Chimica Srl | Processo per la preparazione di 21-idrossi steroidi con controllo della distribuzione epimerica nella posizione c-21 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2149302A1 (en) * | 1971-08-19 | 1973-03-30 | Roussel Uclaf | 21-methyl pregnadienes prepn - used as progestomimetics |
CH629504A5 (en) * | 1977-12-14 | 1982-04-30 | Roussel Uclaf | 19-Norpregnatetraene derivatives |
US4181720A (en) * | 1978-04-05 | 1980-01-01 | Syntex (U.S.A.) Inc. | Corticosteroid antiinflammatory agents |
FR2430953A1 (fr) * | 1978-07-13 | 1980-02-08 | Roussel Uclaf | Nouveaux derives 3,20-dioxo 4,9-diene 21-hydroxyle, leur procede de preparation et leur application comme medicaments |
FR2692267B1 (fr) * | 1992-06-11 | 1995-05-19 | Roussel Uclaf | Nouveau procédé de préparation de composés stéroïdes 20-céto 21alpha-hydroxy et intermédiaires. |
-
1992
- 1992-06-11 FR FR9207047A patent/FR2692267B1/fr not_active Expired - Fee Related
-
1993
- 1993-06-09 MX MX9303454A patent/MX9303454A/es unknown
- 1993-06-10 EP EP93401481A patent/EP0574317B1/fr not_active Expired - Lifetime
- 1993-06-10 ES ES93401481T patent/ES2092785T3/es not_active Expired - Lifetime
- 1993-06-10 HU HU9301694A patent/HU213673B/hu unknown
- 1993-06-10 DE DE69305241T patent/DE69305241T2/de not_active Expired - Lifetime
- 1993-06-10 HU HU9603208A patent/HU221161B1/hu unknown
- 1993-06-10 HU HU9603209A patent/HU221970B1/hu active IP Right Grant
- 1993-06-10 AT AT93401481T patent/ATE143971T1/de active
- 1993-06-10 CA CA002098146A patent/CA2098146C/fr not_active Expired - Lifetime
- 1993-06-10 DE DE10299019C patent/DE10299019I2/de active Active
- 1993-06-10 DK DK93401481.2T patent/DK0574317T3/da active
- 1993-06-11 US US08/075,822 patent/US5399685A/en not_active Expired - Lifetime
- 1993-06-11 JP JP16497993A patent/JP3231901B2/ja not_active Expired - Lifetime
-
1996
- 1996-10-11 GR GR960401133T patent/GR3021337T3/el unknown
-
2001
- 2001-11-02 NL NL300068C patent/NL300068I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
DK0574317T3 (da) | 1996-12-23 |
HU9301694D0 (en) | 1994-01-28 |
DE69305241T2 (de) | 1997-03-06 |
FR2692267A1 (fr) | 1993-12-17 |
HU9603208D0 (en) | 1997-01-28 |
EP0574317B1 (fr) | 1996-10-09 |
JP3231901B2 (ja) | 2001-11-26 |
GR3021337T3 (en) | 1997-01-31 |
HU9603209D0 (en) | 1997-01-28 |
ES2092785T3 (es) | 1996-12-01 |
HU213673B (en) | 1997-09-29 |
FR2692267B1 (fr) | 1995-05-19 |
CA2098146A1 (fr) | 1993-12-12 |
HU221161B1 (en) | 2002-08-28 |
CA2098146C (fr) | 2003-12-30 |
ATE143971T1 (de) | 1996-10-15 |
HUT64557A (en) | 1994-01-28 |
EP0574317A1 (fr) | 1993-12-15 |
DE10299019I1 (de) | 2002-11-07 |
DE69305241D1 (de) | 1996-11-14 |
JPH0665283A (ja) | 1994-03-08 |
HU221970B1 (hu) | 2003-03-28 |
DE10299019I2 (de) | 2008-06-19 |
NL300068I1 (nl) | 2002-02-01 |
US5399685A (en) | 1995-03-21 |
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