MX9302169A - Fenoxialquilisoxazolas de 1,2,4-oxadiazolilo y su uso como agentes antivirales. - Google Patents

Fenoxialquilisoxazolas de 1,2,4-oxadiazolilo y su uso como agentes antivirales.

Info

Publication number
MX9302169A
MX9302169A MX9302169A MX9302169A MX9302169A MX 9302169 A MX9302169 A MX 9302169A MX 9302169 A MX9302169 A MX 9302169A MX 9302169 A MX9302169 A MX 9302169A MX 9302169 A MX9302169 A MX 9302169A
Authority
MX
Mexico
Prior art keywords
antiviral agents
phenoxyalkylisoxazoles
oxadiazolyl
methods
phenoxyaluylisoxazoleas
Prior art date
Application number
MX9302169A
Other languages
English (en)
Spanish (es)
Inventor
Guy Dominic Diana
Theodore John Nitz
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of MX9302169A publication Critical patent/MX9302169A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX9302169A 1992-04-15 1993-04-14 Fenoxialquilisoxazolas de 1,2,4-oxadiazolilo y su uso como agentes antivirales. MX9302169A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/869,287 US5349068A (en) 1992-04-15 1992-04-15 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (1)

Publication Number Publication Date
MX9302169A true MX9302169A (es) 1993-10-01

Family

ID=25353269

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302169A MX9302169A (es) 1992-04-15 1993-04-14 Fenoxialquilisoxazolas de 1,2,4-oxadiazolilo y su uso como agentes antivirales.

Country Status (26)

Country Link
US (3) US5349068A (OSRAM)
EP (1) EP0566199B1 (OSRAM)
JP (1) JP3103845B2 (OSRAM)
KR (1) KR100314158B1 (OSRAM)
AT (1) ATE189958T1 (OSRAM)
AU (1) AU666528B2 (OSRAM)
CA (1) CA2094012C (OSRAM)
CZ (1) CZ285845B6 (OSRAM)
DE (1) DE69327913T2 (OSRAM)
DK (1) DK0566199T3 (OSRAM)
ES (1) ES2143487T3 (OSRAM)
FI (1) FI112229B (OSRAM)
GR (1) GR3033486T3 (OSRAM)
HU (2) HU220606B1 (OSRAM)
IL (1) IL105372A (OSRAM)
MX (1) MX9302169A (OSRAM)
MY (1) MY110191A (OSRAM)
NO (1) NO302700B1 (OSRAM)
NZ (1) NZ247411A (OSRAM)
PH (1) PH30454A (OSRAM)
PT (1) PT566199E (OSRAM)
RU (1) RU2114112C1 (OSRAM)
SG (1) SG50663A1 (OSRAM)
SK (1) SK279786B6 (OSRAM)
TW (1) TW239140B (OSRAM)
UA (1) UA35557C2 (OSRAM)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6528652B1 (en) 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
AU2002313633B2 (en) * 2001-06-08 2007-03-01 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs
US7129359B2 (en) * 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
CA2459376A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
WO2003020270A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
ATE465730T1 (de) 2001-12-07 2010-05-15 Ana Maria Sandino Zusammensetzungen zur steigerung des überlebens von wassertieren, die einem rns-virus ausgesetzt sind
US20060167109A1 (en) * 2002-02-14 2006-07-27 Pevear Daniel C Methods of reducing rhinovirus contagion and related compositions
WO2004058253A1 (en) * 2002-12-18 2004-07-15 Cytovia, Inc. 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
US7259174B2 (en) * 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds
WO2006017505A2 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
MX2008010350A (es) * 2006-02-09 2008-10-31 Schering Corp Formulaciones farmaceuticas.
WO2007095041A2 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
WO2007095039A2 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
CA2671478C (en) 2006-12-13 2015-02-17 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
KR101031584B1 (ko) * 2009-04-21 2011-04-27 파인오토시스템(주) 전면부가 개폐되는 차량용 적외선 조사장치
CN103102348B (zh) * 2011-11-14 2016-06-08 上海交通大学 噁二唑类化合物及其制备方法、药物组合物及其用途
KR20210046649A (ko) 2018-08-21 2021-04-28 교린 세이야꾸 가부시키 가이샤 이환식 헤테로방향환 유도체
WO2021062189A1 (en) * 2019-09-27 2021-04-01 Collaborations Pharmaceuticals, Inc. Isoxazole-3-carboxamide derivatives and their use for treatment of diseases caused by virus infection
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
GB8619433D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Also Published As

Publication number Publication date
CA2094012A1 (en) 1993-10-16
HU220606B1 (hu) 2002-03-28
US5643929A (en) 1997-07-01
HU9301084D0 (en) 1993-06-28
RU2114112C1 (ru) 1998-06-27
SK35393A3 (en) 1994-06-08
DE69327913T2 (de) 2000-10-12
AU666528B2 (en) 1996-02-15
CA2094012C (en) 2001-08-21
HU211320A9 (en) 1995-11-28
GR3033486T3 (en) 2000-09-29
EP0566199A1 (en) 1993-10-20
FI112229B (fi) 2003-11-14
PH30454A (en) 1997-05-28
DK0566199T3 (da) 2000-06-19
AU3688193A (en) 1993-10-21
NO302700B1 (no) 1998-04-14
FI931707L (fi) 1993-10-16
ATE189958T1 (de) 2000-03-15
ES2143487T3 (es) 2000-05-16
SK279786B6 (sk) 1999-03-12
IL105372A (en) 1998-12-27
KR930021637A (ko) 1993-11-22
NO931366L (no) 1993-10-18
CZ285845B6 (cs) 1999-11-17
UA35557C2 (uk) 2001-04-16
NO931366D0 (no) 1993-04-14
KR100314158B1 (ko) 2002-02-19
CZ59793A3 (en) 1994-02-16
SG50663A1 (en) 1998-07-20
IL105372A0 (en) 1993-08-18
US5464848A (en) 1995-11-07
NZ247411A (en) 1994-06-27
US5349068A (en) 1994-09-20
JP3103845B2 (ja) 2000-10-30
DE69327913D1 (de) 2000-04-06
PT566199E (pt) 2000-09-29
TW239140B (OSRAM) 1995-01-21
JPH0649066A (ja) 1994-02-22
HUT65574A (en) 1994-07-28
FI931707A0 (fi) 1993-04-15
MY110191A (en) 1998-02-28
EP0566199B1 (en) 2000-03-01

Similar Documents

Publication Publication Date Title
MX9302169A (es) Fenoxialquilisoxazolas de 1,2,4-oxadiazolilo y su uso como agentes antivirales.
KR860005001A (ko) 세제 조성물
FI93831B (fi) Tetratsolit, jotka ovat verenpainetta alentavien yhdisteiden välituotteita
ES2070660B1 (es) Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales.
ES2194314T3 (es) Derivados de benzopirano sustituidos para el tratamiento de inflamaciones.
AR062931A2 (es) Compuestos que se enlazan a y activan un receptor de la trombopoyetina , composicones farmaceuticas que los contienen y su uso para la preparacion de medicamentos
ES542323A0 (es) Un procedimiento para la preparacion de derivados de la 2 pirimidinil-1-piperazina
ES485621A1 (es) Un procedimiento para la preparacion de derivados de diben- zopirano
AR025756A1 (es) Un compuesto de acido sustituido, composiciones y combinaciones farmaceuticas que lo comprenden y su uso para la preparacion de medicamentos
EE03869B1 (et) Sulfiinhappe derivaadid, nende valmistamine ja kasutamine
ES2036194T3 (es) Derivados n-fosfonilmetoxialquilicos de bases de pirimidina y purina, metodos para su preparacion y composiciones farmaceuticas basadas en ellos, con actividad antivirica.
ES2032899T3 (es) Agente cosmetico para aplicacion externa y su uso.
MX9201731A (es) Nuevas sales de mono-amonio no-higroscopicas.
PT93552A (pt) Processo para a preparacao de derivados de pirrol acriloil-substituidos e de composicoes farmaceuticas que os contem
ES2061546T3 (es) Compuestos quelantes de piridoxamina, quelatos de manganeso (ii) y su uso como agentes de contraste de nmri.
ATE288900T1 (de) Substituierte benzoylcyclohexandione
ES2083625T3 (es) Derivados de n-feniltiourea y uso farmaceutico de los mismos.
ES8202015A1 (es) Un procedimiento para la preparacion de derivados de penici-lina
DK0589322T3 (da) 5-Oxo-dibenzo a,d cyclohepta-1,4-diener samt deres anvendelse som retrovirale midler.
SE9604582D0 (sv) Novel compounds
SE9704272D0 (sv) Novel Compounds
MX9305523A (es) Composiciones quimoterapeuticas mejoradas frente a infecciones microbianas en peces, la reparacion y uso de las mismas.
ES2039291T3 (es) Procedimiento para la obtencion de 3-aminosidnoniminas substituidas y su empleo.
IT1216104B (it) Peptidi ad attivita' farmaceutica.
MX9300133A (es) Nuevas pirido [2,3-d]piridazin-5-onas y pirido [2,3-d] piridazin-5-tionas, procedimiento para su preparacion y composiciones herbicidas que las contienen.