MX9300638A - Derivados del acido aminobenzoico. - Google Patents

Derivados del acido aminobenzoico.

Info

Publication number
MX9300638A
MX9300638A MX9300638A MX9300638A MX9300638A MX 9300638 A MX9300638 A MX 9300638A MX 9300638 A MX9300638 A MX 9300638A MX 9300638 A MX9300638 A MX 9300638A MX 9300638 A MX9300638 A MX 9300638A
Authority
MX
Mexico
Prior art keywords
aminobenzoic acid
derivatives
activity
unidentified
acetylcholine
Prior art date
Application number
MX9300638A
Other languages
English (en)
Inventor
Shuhei Miyazawa
Shigeki Hibi
Hiroyuki Yoshimura
Takashi Mori Mitsuo Nagai
Yorihisa Hoshino
Kouichi Kikuchi Hisash Shibata
Kazuo Hirota Isao Yamatsu
Takashi Yamanaka
Masanori Mizuno
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of MX9300638A publication Critical patent/MX9300638A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Un derivado del ácido aminobenzoico representado por las siguientes fórmulas generales (I), (I-2) o (I-3), o una sal del mismo farmacológicamente aceptable, que exhibe un antagonismo de la serotonina y una actividad aceleradora de la liberación de acetilcolina a una razón bien equilibrada de actividad y que es eficaz como fármaco para pacientes con afecciones gastrointestinales inidentificadas.
MX9300638A 1992-02-04 1993-02-04 Derivados del acido aminobenzoico. MX9300638A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1895992 1992-02-04
JP23553392 1992-09-03

Publications (1)

Publication Number Publication Date
MX9300638A true MX9300638A (es) 1993-08-01

Family

ID=26355729

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300638A MX9300638A (es) 1992-02-04 1993-02-04 Derivados del acido aminobenzoico.

Country Status (18)

Country Link
US (4) US5389643A (es)
EP (1) EP0554794B1 (es)
JP (2) JP2721631B2 (es)
KR (3) KR970005192B1 (es)
CN (1) CN1039909C (es)
AT (1) ATE169015T1 (es)
AU (2) AU653094B2 (es)
CA (1) CA2088702C (es)
DE (1) DE69319939T2 (es)
DK (1) DK0554794T3 (es)
ES (1) ES2118842T3 (es)
FI (1) FI120260B (es)
HU (1) HU221301B1 (es)
MX (1) MX9300638A (es)
NO (1) NO302821B1 (es)
NZ (2) NZ264220A (es)
PH (1) PH31171A (es)
TW (1) TW309521B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30413A (en) * 1992-03-26 1997-05-09 Boehringer Ingelheim Italia Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
FR2762316B1 (fr) * 1997-04-18 1999-12-17 Sanofi Synthelabo Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
WO2005007600A2 (en) * 2003-07-11 2005-01-27 Eisai Co., Ltd. Novel methods using aminobenzoic acid compounds
JPWO2005099698A1 (ja) * 2004-04-15 2008-03-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 安定化された４−アミノ−５−クロロ−Ｎ−［（１Ｒ，３ｒ，５Ｓ）−８−メチル−８−アザビシクロ［３．２．１］オクタ−３−イル］−２−［１−メチルブタ−２−インイルオキシ］ベンズアミド含有組成物
CN114315585B (zh) * 2022-03-04 2022-05-13 中国医学科学院药用植物研究所 一种羟戊苯甲酸双酯化合物及其制备方法和制药应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
EP0220011A3 (en) * 1985-10-12 1990-01-03 Beecham Group Plc Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia
GB8718345D0 (en) * 1987-08-03 1987-09-09 Fordonal Sa N-substituted benzamides
PT100990A (pt) * 1991-10-24 1994-01-31 Smithkline Beecham Plc Derivados de piridina e sua utilizacao como substancia terapeutica

Also Published As

Publication number Publication date
DK0554794T3 (da) 1999-04-26
CN1075145A (zh) 1993-08-11
AU668827B2 (en) 1996-05-16
KR970005192B1 (ko) 1997-04-14
NZ245800A (en) 1995-03-28
CA2088702A1 (en) 1993-08-05
PH31171A (en) 1998-03-20
ES2118842T3 (es) 1998-10-01
AU3217693A (en) 1993-08-05
EP0554794B1 (en) 1998-07-29
US5631402A (en) 1997-05-20
JP2721631B2 (ja) 1998-03-04
KR970002634B1 (en) 1997-03-07
DE69319939D1 (de) 1998-09-03
US5389643A (en) 1995-02-14
US5599972A (en) 1997-02-04
FI120260B (fi) 2009-08-31
US5578603A (en) 1996-11-26
NO930353L (no) 1993-08-05
ATE169015T1 (de) 1998-08-15
KR930017882A (ko) 1993-09-20
HU9300283D0 (en) 1993-04-28
NZ264220A (en) 1995-03-28
CA2088702C (en) 2003-08-12
NO302821B1 (no) 1998-04-27
HUT69691A (en) 1995-09-28
AU6890894A (en) 1994-09-29
AU653094B2 (en) 1994-09-15
FI930462A (fi) 1993-08-05
NO930353D0 (no) 1993-02-02
EP0554794A1 (en) 1993-08-11
TW309521B (es) 1997-07-01
JPH06128254A (ja) 1994-05-10
KR970009570B1 (en) 1997-06-14
DE69319939T2 (de) 1999-02-18
FI930462A0 (fi) 1993-02-02
HU221301B1 (en) 2002-09-28
JPH107674A (ja) 1998-01-13
CN1039909C (zh) 1998-09-23

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