KR970009570B1 - Intermediates of aminobenzoic acid - Google Patents

Intermediates of aminobenzoic acid

Info

Publication number
KR970009570B1
KR970009570B1 KR96027318A KR19960027318A KR970009570B1 KR 970009570 B1 KR970009570 B1 KR 970009570B1 KR 96027318 A KR96027318 A KR 96027318A KR 19960027318 A KR19960027318 A KR 19960027318A KR 970009570 B1 KR970009570 B1 KR 970009570B1
Authority
KR
South Korea
Prior art keywords
group
aminobenzoic acid
chem
intermediates
unindentified
Prior art date
Application number
KR96027318A
Other languages
English (en)
Inventor
Miyazawa Shuhei
Hibi Shighki
Yoshimura Hiroyuki
Mori Takashi
Hosino Yorihisa
Nagai Mitsuo
Nagai Kouich
Kikuchi Kouich
Shibata Hisashi
Hirota Kazuo
Yamanaka Takashi
Yamatsu Isao
Mizuno Masanori
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of KR970009570B1 publication Critical patent/KR970009570B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
KR96027318A 1992-02-04 1996-07-26 Intermediates of aminobenzoic acid KR970009570B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1895992 1992-02-04
JP23553392 1992-09-03
KR1019930001489A KR970005192B1 (ko) 1992-02-04 1993-02-04 아미노 벤조산 유도체

Publications (1)

Publication Number Publication Date
KR970009570B1 true KR970009570B1 (en) 1997-06-14

Family

ID=26355729

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1019930001489A KR970005192B1 (ko) 1992-02-04 1993-02-04 아미노 벤조산 유도체
KR96027317A KR970002634B1 (en) 1992-02-04 1996-07-06 Aminobenzoic acid derivatives
KR96027318A KR970009570B1 (en) 1992-02-04 1996-07-26 Intermediates of aminobenzoic acid

Family Applications Before (2)

Application Number Title Priority Date Filing Date
KR1019930001489A KR970005192B1 (ko) 1992-02-04 1993-02-04 아미노 벤조산 유도체
KR96027317A KR970002634B1 (en) 1992-02-04 1996-07-06 Aminobenzoic acid derivatives

Country Status (18)

Country Link
US (4) US5389643A (ko)
EP (1) EP0554794B1 (ko)
JP (2) JP2721631B2 (ko)
KR (3) KR970005192B1 (ko)
CN (1) CN1039909C (ko)
AT (1) ATE169015T1 (ko)
AU (2) AU653094B2 (ko)
CA (1) CA2088702C (ko)
DE (1) DE69319939T2 (ko)
DK (1) DK0554794T3 (ko)
ES (1) ES2118842T3 (ko)
FI (1) FI120260B (ko)
HU (1) HU221301B1 (ko)
MX (1) MX9300638A (ko)
NO (1) NO302821B1 (ko)
NZ (2) NZ245800A (ko)
PH (1) PH31171A (ko)
TW (1) TW309521B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30413A (en) * 1992-03-26 1997-05-09 Boehringer Ingelheim Italia Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
FR2762316B1 (fr) * 1997-04-18 1999-12-17 Sanofi Synthelabo Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
WO2005007600A2 (en) * 2003-07-11 2005-01-27 Eisai Co., Ltd. Novel methods using aminobenzoic acid compounds
WO2005099698A1 (ja) * 2004-04-15 2005-10-27 Eisai R & D Management Co., Ltd. 安定化された４－アミノ－５－クロロ－Ｎ－［（１Ｒ，３ｒ，５Ｓ）－８－メチル－８－アザビシクロ［３．２．１］オクタ－３－イル]－２－［１－メチルブタ－２－インイルオキシ］ベンズアミド含有組成物
CN114315585B (zh) * 2022-03-04 2022-05-13 中国医学科学院药用植物研究所 一种羟戊苯甲酸双酯化合物及其制备方法和制药应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
EP0220011A3 (en) * 1985-10-12 1990-01-03 Beecham Group Plc Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia
GB8718345D0 (en) * 1987-08-03 1987-09-09 Fordonal Sa N-substituted benzamides
MX9206075A (es) * 1991-10-24 1993-04-01 Smithkline Beecham Plc Nuevos compuestos antagonistas del receptor 5-hidroxitriptamina y composiciones farmaceuticas que los contienen

Also Published As

Publication number Publication date
FI930462A (fi) 1993-08-05
HUT69691A (en) 1995-09-28
DE69319939D1 (de) 1998-09-03
FI120260B (fi) 2009-08-31
AU653094B2 (en) 1994-09-15
CN1075145A (zh) 1993-08-11
AU6890894A (en) 1994-09-29
NO930353D0 (no) 1993-02-02
EP0554794A1 (en) 1993-08-11
JPH107674A (ja) 1998-01-13
PH31171A (en) 1998-03-20
FI930462A0 (fi) 1993-02-02
NZ264220A (en) 1995-03-28
JP2721631B2 (ja) 1998-03-04
KR970005192B1 (ko) 1997-04-14
DK0554794T3 (da) 1999-04-26
KR930017882A (ko) 1993-09-20
HU9300283D0 (en) 1993-04-28
TW309521B (ko) 1997-07-01
AU3217693A (en) 1993-08-05
US5578603A (en) 1996-11-26
ATE169015T1 (de) 1998-08-15
CN1039909C (zh) 1998-09-23
HU221301B1 (en) 2002-09-28
DE69319939T2 (de) 1999-02-18
MX9300638A (es) 1993-08-01
ES2118842T3 (es) 1998-10-01
AU668827B2 (en) 1996-05-16
CA2088702C (en) 2003-08-12
EP0554794B1 (en) 1998-07-29
JPH06128254A (ja) 1994-05-10
US5631402A (en) 1997-05-20
KR970002634B1 (en) 1997-03-07
NZ245800A (en) 1995-03-28
NO930353L (no) 1993-08-05
US5389643A (en) 1995-02-14
US5599972A (en) 1997-02-04
NO302821B1 (no) 1998-04-27
CA2088702A1 (en) 1993-08-05

Similar Documents

Publication Publication Date Title
EP0610958A3 (en) Intermediates for the preparation of derivatives of 4-oxoquinoline-3-carboxylic acid.
DE69428142T2 (de) Quinolin- oder Quinazolinderivate, deren Herstellung und Verwendung
AU1302388A (en) Method of treating anxiety with tetrahydrobenz(c,d)indole-6- carboxamides
AU626740B2 (en) Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments
KR970009570B1 (en) Intermediates of aminobenzoic acid
HU9503090D0 (en) Novel bisoxadiazolidine derivative
AU8003594A (en) Quinolinecarboxylic acid derivative and salt thereof
AU655869B2 (en) An amphoteric tricyclic compound
DE68913099D1 (de) Amino-substituierte verbrückte azabicyclische Chinoloncarbonsäure und Ester.
AU2013888A (en) Uricosuric composition

Legal Events

Date Code Title Description
A107 Divisional application of patent
A201 Request for examination
E902 Notification of reason for refusal
AMND Amendment
E601 Decision to refuse application
J2X1 Appeal (before the patent court)

Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL

G160 Decision to publish patent application
B701 Decision to grant
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20060908

Year of fee payment: 10

LAPS Lapse due to unpaid annual fee