MX9207171A - Preparaciones farmaceuticas a liberacion programada. - Google Patents
Preparaciones farmaceuticas a liberacion programada.Info
- Publication number
- MX9207171A MX9207171A MX9207171A MX9207171A MX9207171A MX 9207171 A MX9207171 A MX 9207171A MX 9207171 A MX9207171 A MX 9207171A MX 9207171 A MX9207171 A MX 9207171A MX 9207171 A MX9207171 A MX 9207171A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical preparations
- scheduled release
- ambroxol hydrochloride
- delayed
- preparations
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- QNVKOSLOVOTXKF-UHFFFAOYSA-N 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydron;chloride Chemical compound Cl.NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1 QNVKOSLOVOTXKF-UHFFFAOYSA-N 0.000 abstract 2
- 229960000985 ambroxol hydrochloride Drugs 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención concierne el procedimiento para la elaboración de preparaciones a liberación programada (retardada) de ambroxol clorhidrato. Las preparaciones farmacéuticas son elaboradas como microgránulos con un perfil de liberación retardada, adecuado para obtener niveles terapéuticos suficientes de ambroxol clorhidrato en el curso de las 24 horas recesivas a la administración en una sola toma de una dosis única.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI913318A IT1252185B (it) | 1991-12-11 | 1991-12-11 | Preparazioni farmaceutiche a liberazione programmata |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9207171A true MX9207171A (es) | 1994-01-31 |
Family
ID=11361308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9207171A MX9207171A (es) | 1991-12-11 | 1992-12-11 | Preparaciones farmaceuticas a liberacion programada. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6251429B1 (es) |
EP (1) | EP0546846B1 (es) |
JP (1) | JPH05320044A (es) |
DE (1) | DE69217020T2 (es) |
ES (1) | ES2099226T3 (es) |
GR (1) | GR3022416T3 (es) |
IT (1) | IT1252185B (es) |
MX (1) | MX9207171A (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5070568A1 (es) * | 1998-05-22 | 2001-08-28 | Eurand Internatrional Spa | Proceso de aplicacion de capas y aparato para efectuarlo |
DE19933148A1 (de) * | 1999-07-20 | 2001-01-25 | Boehringer Ingelheim Int | Ambroxolhaltige Lutschtablette |
JP4644397B2 (ja) | 2001-09-05 | 2011-03-02 | 信越化学工業株式会社 | 難溶性薬物を含む医薬用固形製剤の製造方法 |
ITMI20032463A1 (it) * | 2003-12-16 | 2005-06-17 | Advance Holdings Ltd | Soluzione acquosa concentrata a base di ambroxolo |
DE102004021992A1 (de) * | 2004-05-03 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Topische Zubereitung enthaltend Ambroxol |
CN1294907C (zh) * | 2004-10-11 | 2007-01-17 | 成都拜特尔药业有限公司 | 盐酸氨溴索颗粒剂 |
CN101862305B (zh) * | 2009-04-20 | 2014-05-07 | 北京德众万全药物技术开发有限公司 | 一种盐酸氨溴索缓释微丸及制备方法 |
JP6084355B2 (ja) * | 2010-05-06 | 2017-02-22 | 大正製薬株式会社 | アンブロキソール含有製剤粒子 |
CN105726489A (zh) * | 2014-12-09 | 2016-07-06 | 澳美制药厂有限公司 | 盐酸氨溴索缓释制剂及其制备方法 |
CN105748443B (zh) * | 2016-04-25 | 2018-09-11 | 华润双鹤利民药业(济南)有限公司 | 一种盐酸氨溴索缓释胶囊及其生产工艺 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3317558A1 (de) * | 1983-05-13 | 1984-11-15 | Dietrich Dr.med. Sta. Eulalia Ibiza Reichert | Orales antischnarchmittel |
AU574360B2 (en) * | 1983-05-13 | 1988-07-07 | Reichert, D. | Antisnoring agent |
DE3317530A1 (de) * | 1983-05-13 | 1984-11-15 | Dietrich Dr.med. Sta. Eulalia Ibiza Reichert | Antischnarchmittel |
ATE45106T1 (de) * | 1984-05-18 | 1989-08-15 | Univ Washington | Verfahren zur einkapselung von teilchen oder von tropfen. |
DE3524003A1 (de) * | 1985-07-04 | 1987-01-08 | Heumann Ludwig & Co Gmbh | Arzneimittelgranulat mit verzoegerter wirkstofffreisetzung und verfahren zu seiner herstellung |
SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
JPH0761961B2 (ja) * | 1986-06-24 | 1995-07-05 | 信越化学工業株式会社 | 被覆薬剤の製造方法 |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4996047A (en) * | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
IT1227899B (it) * | 1988-12-23 | 1991-05-14 | Poli Ind Chimica Spa | Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5376386A (en) * | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
US5084287A (en) * | 1990-03-15 | 1992-01-28 | Warner-Lambert Company | Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat |
US5213811A (en) * | 1991-09-13 | 1993-05-25 | Sterling Drug Inc. | Oral sustained-release drug compositions |
US5167964A (en) * | 1992-02-14 | 1992-12-01 | Warner-Lambert Company | Semi-enteric drug delivery systems and methods for preparing same |
DE19539361A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung |
JP2000516222A (ja) * | 1996-08-15 | 2000-12-05 | ロザン ファルマ ゲゼルシャフトミットベシュレンクテル ハフツング | 嚥下が容易な経口医薬組成物 |
-
1991
- 1991-12-11 IT ITMI913318A patent/IT1252185B/it active IP Right Grant
-
1992
- 1992-12-11 EP EP92311328A patent/EP0546846B1/en not_active Expired - Lifetime
- 1992-12-11 DE DE69217020T patent/DE69217020T2/de not_active Expired - Fee Related
- 1992-12-11 MX MX9207171A patent/MX9207171A/es unknown
- 1992-12-11 JP JP4331350A patent/JPH05320044A/ja active Pending
- 1992-12-11 ES ES92311328T patent/ES2099226T3/es not_active Expired - Lifetime
-
1995
- 1995-01-30 US US08/380,218 patent/US6251429B1/en not_active Expired - Fee Related
-
1997
- 1997-01-29 GR GR970400140T patent/GR3022416T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ITMI913318A1 (it) | 1993-06-11 |
JPH05320044A (ja) | 1993-12-03 |
GR3022416T3 (en) | 1997-04-30 |
EP0546846B1 (en) | 1997-01-22 |
EP0546846A1 (en) | 1993-06-16 |
ES2099226T3 (es) | 1997-05-16 |
US6251429B1 (en) | 2001-06-26 |
DE69217020D1 (de) | 1997-03-06 |
DE69217020T2 (de) | 1997-07-31 |
ITMI913318A0 (it) | 1991-12-11 |
IT1252185B (it) | 1995-06-05 |
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