AU640963B2
(en)
*
|
1989-11-09 |
1993-09-09 |
MEDA Pharma S.a.r.l |
Heteroatoms-containing tricyclic compounds
|
FI921595A
(fi)
*
|
1991-04-17 |
1992-10-18 |
American Home Prod |
Rapamycinkarbamater
|
US5565560A
(en)
*
|
1991-05-13 |
1996-10-15 |
Merck & Co., Inc. |
O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
|
US5262533A
(en)
*
|
1991-05-13 |
1993-11-16 |
Merck & Co., Inc. |
Amino O-aryl macrolides having immunosuppressive activity
|
US5247076A
(en)
*
|
1991-09-09 |
1993-09-21 |
Merck & Co., Inc. |
Imidazolidyl macrolides having immunosuppressive activity
|
US5284840A
(en)
*
|
1992-06-12 |
1994-02-08 |
Merck & Co., Inc. |
Alkylidene macrolides having immunosuppressive activity
|
US5284877A
(en)
*
|
1992-06-12 |
1994-02-08 |
Merck & Co., Inc. |
Alkyl and alkenyl macrolides having immunosuppressive activity
|
EP1266900A1
(en)
*
|
1992-10-13 |
2002-12-18 |
Wyeth |
Carbamates of rapamycin
|
US5262423A
(en)
*
|
1992-10-29 |
1993-11-16 |
American Home Products Corporation |
Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents
|
US5258389A
(en)
*
|
1992-11-09 |
1993-11-02 |
Merck & Co., Inc. |
O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
|
US5260300A
(en)
|
1992-11-19 |
1993-11-09 |
American Home Products Corporation |
Rapamycin carbonate esters as immuno-suppressant agents
|
US5310903A
(en)
*
|
1993-03-05 |
1994-05-10 |
Merck & Co., Inc. |
Imidazolidyl rapamycin derivatives
|
US5310901A
(en)
*
|
1993-03-05 |
1994-05-10 |
Merck & Co., Inc. |
O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynlheteroarylrapamycin derivatives
|
GB9307491D0
(en)
*
|
1993-04-08 |
1993-06-02 |
Sandoz Ltd |
Organic compounds
|
USRE40596E1
(en)
*
|
1993-04-08 |
2008-12-02 |
Novartis Ag |
Rapamycin assay
|
US5504091A
(en)
*
|
1993-04-23 |
1996-04-02 |
American Home Products Corporation |
Biotin esters of rapamycin
|
US7279561B1
(en)
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
AU6711994A
(en)
*
|
1993-04-23 |
1994-11-21 |
American Home Products Corporation |
Rapamycin conjugates and antibodies
|
EP0710110B1
(en)
|
1993-04-23 |
2002-03-06 |
Abbott Laboratories |
Antibodies of ring opened rapamycins
|
US5527907A
(en)
*
|
1993-11-19 |
1996-06-18 |
Abbott Laboratories |
Macrolide immunomodulators
|
CA2175215C
(en)
*
|
1993-11-19 |
2008-06-03 |
Yat Sun Or |
Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
|
SK78196A3
(en)
*
|
1993-12-17 |
1997-02-05 |
Sandoz Ag |
Rapamycin demethoxy-derivatives, preparation method thereof and pharmaceutical agent containing them
|
US5389639A
(en)
*
|
1993-12-29 |
1995-02-14 |
American Home Products Company |
Amino alkanoic esters of rapamycin
|
US5362718A
(en)
*
|
1994-04-18 |
1994-11-08 |
American Home Products Corporation |
Rapamycin hydroxyesters
|
US5693648A
(en)
*
|
1994-09-30 |
1997-12-02 |
Merck & Co., Inc. |
O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
|
PE52896A1
(es)
|
1994-10-26 |
1996-12-12 |
Novartis Ag |
Composicion farmaceutica
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
RU2158267C2
(ru)
|
1995-06-09 |
2000-10-27 |
Новартис Аг |
Производные рапамицина и фармацевтическая композиция на их основе
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
US7399480B2
(en)
|
1997-09-26 |
2008-07-15 |
Abbott Laboratories |
Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
|
US6890546B2
(en)
|
1998-09-24 |
2005-05-10 |
Abbott Laboratories |
Medical devices containing rapamycin analogs
|
US20030129215A1
(en)
|
1998-09-24 |
2003-07-10 |
T-Ram, Inc. |
Medical devices containing rapamycin analogs
|
US6015815A
(en)
|
1997-09-26 |
2000-01-18 |
Abbott Laboratories |
Tetrazole-containing rapamycin analogs with shortened half-lives
|
US8257725B2
(en)
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
US8057816B2
(en)
|
1997-09-26 |
2011-11-15 |
Abbott Laboratories |
Compositions and methods of administering paclitaxel with other drugs using medical devices
|
US8394398B2
(en)
|
1997-09-26 |
2013-03-12 |
Abbott Laboratories |
Methods of administering rapamycin analogs with anti-inflammatories using medical devices
|
US7378105B2
(en)
|
1997-09-26 |
2008-05-27 |
Abbott Laboratories |
Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
|
US7357942B2
(en)
|
1997-09-26 |
2008-04-15 |
Abbott Laboratories |
Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
|
US8257726B2
(en)
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
|
US7455853B2
(en)
|
1998-09-24 |
2008-11-25 |
Abbott Cardiovascular Systems Inc. |
Medical devices containing rapamycin analogs
|
US7960405B2
(en)
|
1998-09-24 |
2011-06-14 |
Abbott Laboratories |
Compounds and methods for treatment and prevention of diseases
|
US8257724B2
(en)
|
1998-09-24 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
AU2725000A
(en)
|
1999-01-13 |
2000-08-01 |
Bayer Corporation |
Omega-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
|
ES2222222T3
(es)
*
|
1999-08-18 |
2005-02-01 |
Wyeth |
Esteres hidrosolubles de sdz-rad.
|
ATE264863T1
(de)
|
1999-08-24 |
2004-05-15 |
Ariad Gene Therapeutics Inc |
28-epirapaloge
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
GB0008785D0
(en)
|
2000-04-10 |
2000-05-31 |
Novartis Ag |
Organic compounds
|
WO2002024706A2
(en)
*
|
2000-09-19 |
2002-03-28 |
Wyeth |
Water soluble rapamycin esters
|
MXPA04007832A
(es)
|
2002-02-11 |
2005-09-08 |
Bayer Pharmaceuticals Corp |
Aril-ureas con actividad inhibitoria de angiogenesis.
|
CN100349627C
(zh)
|
2002-09-06 |
2007-11-21 |
艾博特公司 |
含有水合抑制剂的医疗装置及其制备方法
|
WO2004060283A2
(en)
|
2002-12-16 |
2004-07-22 |
Nitromed, Inc. |
Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use
|
DE60331367D1
(de)
|
2002-12-30 |
2010-04-01 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
US7160867B2
(en)
*
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
WO2004113274A2
(en)
|
2003-05-20 |
2004-12-29 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
US8431145B2
(en)
|
2004-03-19 |
2013-04-30 |
Abbott Laboratories |
Multiple drug delivery from a balloon and a prosthesis
|
DK1735321T3
(da)
|
2004-04-14 |
2009-01-12 |
Wyeth Corp |
Fremgangsmåde til fremstilling af rapamycin 42-estere og FK-506 32-estere med dicarboxylsyre, precursors for rapamycinkonjugater og antistoffer
|
US7268144B2
(en)
|
2004-04-14 |
2007-09-11 |
Wyeth |
Regiospecific synthesis of rapamycin 42-ester derivatives
|
EP1768662A2
(en)
|
2004-06-24 |
2007-04-04 |
Novartis Vaccines and Diagnostics, Inc. |
Small molecule immunopotentiators and assays for their detection
|
AU2006213588B2
(en)
|
2005-02-09 |
2011-11-17 |
Santen Pharmaceutical Co., Ltd. |
Liquid formulations for treatment of diseases or conditions
|
MX2007010892A
(es)
|
2005-03-07 |
2007-12-05 |
Wyeth Corp |
Isomero de oxepano de 42-o-(2-hidroxi)etil-rapamicina.
|
EP3138531A1
(en)
|
2005-03-23 |
2017-03-08 |
Abbott Laboratories |
Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
|
EP2327429B1
(en)
|
2005-03-23 |
2014-09-17 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
RU2443418C2
(ru)
|
2005-07-20 |
2012-02-27 |
Новартис Аг |
КОМБИНАЦИЯ ПИРИМИДИЛАМИНОБЕНЗАМИДА И ИНГИБИТОРА КИНАЗ mTOR
|
NZ568694A
(en)
|
2005-11-09 |
2011-09-30 |
Zalicus Inc |
Method, compositions, and kits for the treatment of medical conditions
|
US7838023B2
(en)
|
2005-11-16 |
2010-11-23 |
Nitromed, Inc. |
Furoxan compounds, compositions and methods of use
|
KR20080071600A
(ko)
|
2005-11-21 |
2008-08-04 |
노파르티스 아게 |
Mtor 억제제를 사용하는 신경내분비 종양 치료법
|
US7700614B2
(en)
|
2005-12-14 |
2010-04-20 |
Abbott Laboratories |
One pot synthesis of tetrazole derivatives of rapamycin
|
US8492400B2
(en)
|
2006-02-09 |
2013-07-23 |
Santen Pharmaceutical Co., Ltd. |
Stable formulations, and methods of their preparation and use
|
US7622477B2
(en)
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
US7678901B2
(en)
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
US20070203169A1
(en)
*
|
2006-02-28 |
2007-08-30 |
Zhao Jonathon Z |
Isomers and 42-epimers of rapamycin ester analogs, methods of making and using the same
|
CN103127100A
(zh)
|
2006-03-23 |
2013-06-05 |
参天制药株式会社 |
用于与血管通透性有关的疾病或病症的制剂和方法
|
US7883855B2
(en)
|
2006-07-21 |
2011-02-08 |
Abbott Laboratories |
Immunosuppressant drug extraction reagent for immunoassays
|
WO2008042216A2
(en)
|
2006-09-28 |
2008-04-10 |
Follica, Inc. |
Methods, kits, and compositions for generating new hair follicles and growing hair
|
US10265407B2
(en)
|
2007-02-15 |
2019-04-23 |
Yale University |
Modular nanodevices for smart adaptable vaccines
|
WO2009078875A1
(en)
|
2007-12-19 |
2009-06-25 |
Abbott Laboratories |
Immunosuppressant drug extraction reagent for immunoassays
|
CA2711765A1
(en)
|
2008-01-11 |
2009-07-16 |
Massachusetts Eye & Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
US20100048913A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
JP2012516900A
(ja)
|
2009-02-05 |
2012-07-26 |
トーカイ ファーマシューティカルズ,インク. |
ステロイド性cyp17阻害剤/抗アンドロゲン剤の新しいプロドラッグ
|
EP2470179B1
(en)
|
2009-08-26 |
2017-11-29 |
Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. |
Sustained release delivery systems for the prevention and treatment of head and neck cancers
|
US8951595B2
(en)
|
2009-12-11 |
2015-02-10 |
Abbott Cardiovascular Systems Inc. |
Coatings with tunable molecular architecture for drug-coated balloon
|
JP5918214B2
(ja)
|
2010-04-13 |
2016-05-18 |
ノバルティス アーゲー |
がんを治療するためのサイクリン依存性キナーゼ4またはサイクリン依存性キナーゼ(cdk4/6)阻害剤およびmtor阻害剤を含む組合せ
|
SG184311A1
(en)
|
2010-04-16 |
2012-11-29 |
Novartis Ag |
Combination of organic compounds
|
KR101253399B1
(ko)
|
2010-10-26 |
2013-04-11 |
영남대학교 산학협력단 |
아포지단백질 a-i 및 그 변이체를 포함한 재조합 고밀도지단백질을 이용한 라파마이신 제형
|
JP6170840B2
(ja)
|
2011-03-11 |
2017-07-26 |
ベス イスラエル デアコネス メディカル センター インコーポレイテッド |
抗cd40抗体及びその使用
|
NZ615593A
(en)
|
2011-04-25 |
2015-05-29 |
Novartis Ag |
Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor
|
CN104519907A
(zh)
|
2012-03-23 |
2015-04-15 |
昆士兰大学 |
免疫调节剂及其用途
|
US9597385B2
(en)
|
2012-04-23 |
2017-03-21 |
Allertein Therapeutics, Llc |
Nanoparticles for treatment of allergy
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
US9757432B2
(en)
|
2012-11-14 |
2017-09-12 |
Ohio State Innovation Foundation |
Materials and methods useful for treating glioblastorna
|
SG11201507093WA
(en)
|
2013-03-14 |
2015-10-29 |
Univ Maryland Baltimore Office Of Technology Transfer |
Androgen receptor down-regulating agents and uses thereof
|
SG11201508113SA
(en)
|
2013-04-03 |
2015-10-29 |
Allertein Therapeutics Llc |
Novel nanoparticle compositions
|
WO2014184734A1
(en)
|
2013-05-14 |
2014-11-20 |
Novartis Ag |
Markers associated with mtor inhibition
|
CN105283553B
(zh)
|
2013-06-11 |
2021-06-25 |
克隆技术实验室有限公司 |
蛋白质富集的微泡及其制备和使用方法
|
RU2016104643A
(ru)
|
2013-08-12 |
2017-09-19 |
Токай Фармасьютикалз, Инк. |
Биомаркёры для лечения неопластических заболеваний с применением нацеленных на андроген методов лечения
|
WO2015044854A1
(en)
|
2013-09-24 |
2015-04-02 |
Novartis Ag |
Markers associated with mtor inhibition
|
AU2015216590A1
(en)
|
2014-02-11 |
2016-06-30 |
Novartis Ag |
Pharmaceutical combinations comprising a PI3K inhibitor for the treatment of cancer
|
US10300070B2
(en)
|
2014-03-27 |
2019-05-28 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
US10258639B2
(en)
|
2014-05-06 |
2019-04-16 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy
|
CN105461738B
(zh)
*
|
2014-06-03 |
2019-03-08 |
中国人民解放军军事医学科学院毒物药物研究所 |
一种雷帕霉素衍生物、其制备方法、其药物组合物及用途
|
CN107073066B
(zh)
|
2014-09-11 |
2021-09-17 |
加利福尼亚大学董事会 |
mTORC1抑制剂
|
ES2887602T3
(es)
|
2015-09-04 |
2021-12-23 |
Primatope Therapeutics Inc |
Anticuerpos anti-CD40 humanizados y usos de los mismos
|
US20190290631A1
(en)
|
2016-05-27 |
2019-09-26 |
Nippon Kayaku Kabushiki Kaisha |
Pharmaceutical composition comprising rapamycin or derivative thereof
|
US10682340B2
(en)
|
2016-06-30 |
2020-06-16 |
Durect Corporation |
Depot formulations
|
EP3478285A4
(en)
|
2016-06-30 |
2020-07-22 |
Durect Corporation |
DEPOSIT FORMULATIONS
|
CA3048217A1
(en)
|
2016-12-22 |
2018-06-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
EA201990127A1
(ru)
|
2016-12-30 |
2020-08-18 |
Дьюрект Корпорейшн |
Депо-препарат
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
IL293443A
(en)
|
2017-09-08 |
2022-07-01 |
Amgen Inc |
kras g12c inhibitors and methods of using them
|
WO2019212990A1
(en)
|
2018-05-01 |
2019-11-07 |
Revolution Medicines, Inc. |
C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors
|
IL312291A
(en)
|
2018-05-01 |
2024-06-01 |
Revolution Medicines Inc |
C-26-linked rapamycin analogs as MTOR inhibitors
|
JP7361722B2
(ja)
|
2018-05-04 |
2023-10-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤及び同一物の使用方法
|
JP7266043B2
(ja)
|
2018-05-04 |
2023-04-27 |
アムジエン・インコーポレーテツド |
KRas G12C阻害剤及びそれを使用する方法
|
JP7361720B2
(ja)
|
2018-05-10 |
2023-10-16 |
アムジエン・インコーポレーテツド |
がんの治療のためのkras g12c阻害剤
|
ES2938987T3
(es)
|
2018-06-01 |
2023-04-18 |
Amgen Inc |
Inhibidores de KRAS G12c y métodos de uso de los mismos
|
JP7357644B2
(ja)
|
2018-06-11 |
2023-10-06 |
アムジエン・インコーポレーテツド |
がんを処置するためのkras g12c阻害剤
|
MA51848A
(fr)
|
2018-06-12 |
2021-04-21 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
JP2020090482A
(ja)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
MA55136A
(fr)
|
2018-11-19 |
2022-02-23 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
MX2021007157A
(es)
|
2018-12-20 |
2021-08-16 |
Amgen Inc |
Heteroarilamidas utiles como inhibidores de kif18a.
|
EA202191730A1
(ru)
|
2018-12-20 |
2021-08-24 |
Эмджен Инк. |
Ингибиторы kif18a
|
AU2019403488A1
(en)
|
2018-12-20 |
2021-06-24 |
Amgen Inc. |
KIF18A inhibitors
|
WO2020132649A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Heteroaryl amides useful as kif18a inhibitors
|
WO2020180770A1
(en)
|
2019-03-01 |
2020-09-10 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
EP3931195A1
(en)
|
2019-03-01 |
2022-01-05 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
CN114144414A
(zh)
|
2019-05-21 |
2022-03-04 |
美国安进公司 |
固态形式
|
AU2020325115A1
(en)
|
2019-08-02 |
2022-03-17 |
Amgen Inc. |
Pyridine derivatives as KIF18A inhibitors
|
AU2020326627A1
(en)
|
2019-08-02 |
2022-03-17 |
Amgen Inc. |
KIF18A inhibitors
|
EP4007753A1
(en)
|
2019-08-02 |
2022-06-08 |
Amgen Inc. |
Kif18a inhibitors
|
MX2022001181A
(es)
|
2019-08-02 |
2022-02-22 |
Amgen Inc |
Inhibidores de kif18a.
|
EP4031542A4
(en)
|
2019-09-18 |
2023-10-25 |
Merck Sharp & Dohme LLC |
KRAS G12C MUTANT SMALL MOLECULE INHIBITORS
|
WO2021081212A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
KR20220106980A
(ko)
|
2019-10-28 |
2022-08-01 |
머크 샤프 앤드 돔 코포레이션 |
Kras g12c 돌연변이체의 소분자 억제제
|
US20230023023A1
(en)
|
2019-10-31 |
2023-01-26 |
Taiho Pharmaceutical Co., Ltd. |
4-aminobut-2-enamide derivatives and salts thereof
|
KR20220109408A
(ko)
|
2019-11-04 |
2022-08-04 |
레볼루션 메디슨즈, 인크. |
Ras 억제제
|
CN115873020A
(zh)
|
2019-11-04 |
2023-03-31 |
锐新医药公司 |
Ras抑制剂
|
EP4055028A1
(en)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
CN114901662A
(zh)
|
2019-11-08 |
2022-08-12 |
锐新医药公司 |
双环杂芳基化合物及其用途
|
TW202132271A
(zh)
|
2019-11-14 |
2021-09-01 |
美商安進公司 |
Kras g12c抑制劑化合物之改善的合成
|
JP2023501528A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の改善された合成
|
EP4065231A1
(en)
|
2019-11-27 |
2022-10-05 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
WO2021106231A1
(en)
|
2019-11-29 |
2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
A compound having inhibitory activity against kras g12d mutation
|
BR112022010086A2
(pt)
|
2020-01-07 |
2022-09-06 |
Revolution Medicines Inc |
Dosagem do inibidor de shp2 e métodos de tratamento de câncer
|
US20230174518A1
(en)
|
2020-04-24 |
2023-06-08 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
EP4183395A1
(en)
|
2020-07-15 |
2023-05-24 |
Taiho Pharmaceutical Co., Ltd. |
Pyrimidine compound-containing combination to be used in tumor treatment
|
JP2023541236A
(ja)
|
2020-09-03 |
2023-09-29 |
レボリューション メディシンズ インコーポレイテッド |
Shp2変異を有する悪性腫瘍を治療するためのsos1阻害剤の使用
|
TW202227460A
(zh)
|
2020-09-15 |
2022-07-16 |
美商銳新醫藥公司 |
Ras抑制劑
|
CN117396472A
(zh)
|
2020-12-22 |
2024-01-12 |
上海齐鲁锐格医药研发有限公司 |
Sos1抑制剂及其用途
|
AU2022270116A1
(en)
|
2021-05-05 |
2023-12-21 |
Revolution Medicines, Inc. |
Ras inhibitors
|
EP4334325A1
(en)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
WO2022235866A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
EP4347041A1
(en)
|
2021-05-28 |
2024-04-10 |
Taiho Pharmaceutical Co., Ltd. |
Small molecule inhibitors of kras mutated proteins
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
TW202340214A
(zh)
|
2021-12-17 |
2023-10-16 |
美商健臻公司 |
做為shp2抑制劑之吡唑并吡𠯤化合物
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|