MX388092B - Metodos mejorados para la modificacion de acido nucleicos diana. - Google Patents

Metodos mejorados para la modificacion de acido nucleicos diana.

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Publication number
MX388092B
MX388092B MX2018013256A MX2018013256A MX388092B MX 388092 B MX388092 B MX 388092B MX 2018013256 A MX2018013256 A MX 2018013256A MX 2018013256 A MX2018013256 A MX 2018013256A MX 388092 B MX388092 B MX 388092B
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MX
Mexico
Prior art keywords
target nucleic
nucleic acids
improved methods
acids modification
modification
Prior art date
Application number
MX2018013256A
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English (en)
Other versions
MX2018013256A (es
Inventor
Wilde Chris De
Mcelver John A
Neuteboom Leendert W
Max Fabian Felle
Pinho Barroco Rosa De
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Basf Plant Science Co Gmbh
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58640844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX388092(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Plant Science Co Gmbh filed Critical Basf Plant Science Co Gmbh
Publication of MX2018013256A publication Critical patent/MX2018013256A/es
Publication of MX388092B publication Critical patent/MX388092B/es

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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]

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Abstract

La presente invención se refiere a métodos para la modificación de ácidos nucleicos diana. El método implica un constructo en donde el ARN guía está ligado de manera covalente al ARN donante (NA de fusión) que se debe introducir en el ácido nucleico diana mediante recombinación homóloga y se basa en la introducción de una nucleasa, por ejemplo, CRISPR o TALEN, en la célula que contiene el ácido nucleico diana. El NA de fusión se puede introducir como un vector de ADN.
MX2018013256A 2016-04-29 2017-04-20 Metodos mejorados para la modificacion de acido nucleicos diana. MX388092B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP16167774 2016-04-29
EP16167773 2016-04-29
EP17156018 2017-02-14
PCT/EP2017/059331 WO2017186550A1 (en) 2016-04-29 2017-04-20 Improved methods for modification of target nucleic acids

Publications (2)

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MX2018013256A MX2018013256A (es) 2019-06-24
MX388092B true MX388092B (es) 2025-03-19

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MX2018013256A MX388092B (es) 2016-04-29 2017-04-20 Metodos mejorados para la modificacion de acido nucleicos diana.
MX2021009235A MX2021009235A (es) 2016-04-29 2018-10-29 Metodos mejorados para la modificacion de acidos nucleicos diana.

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US (5) US11608499B2 (es)
EP (5) EP3448990B1 (es)
JP (2) JP7184648B2 (es)
KR (3) KR102370675B1 (es)
CN (1) CN109072207B (es)
AU (5) AU2017256517B2 (es)
CA (1) CA3022475A1 (es)
CL (1) CL2018003074A1 (es)
DK (1) DK3448990T5 (es)
IL (1) IL262409B2 (es)
MX (2) MX388092B (es)
WO (1) WO2017186550A1 (es)

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