MX384709B - Proceso de hidrogenación catalítico para preparar pirazoles. - Google Patents
Proceso de hidrogenación catalítico para preparar pirazoles.Info
- Publication number
- MX384709B MX384709B MX2018009453A MX2018009453A MX384709B MX 384709 B MX384709 B MX 384709B MX 2018009453 A MX2018009453 A MX 2018009453A MX 2018009453 A MX2018009453 A MX 2018009453A MX 384709 B MX384709 B MX 384709B
- Authority
- MX
- Mexico
- Prior art keywords
- catalytic hydrogenation
- hydrogenation process
- brã
- acids
- pyrazoles
- Prior art date
Links
- 150000003217 pyrazoles Chemical class 0.000 title abstract 2
- 238000009903 catalytic hydrogenation reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000007513 acids Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 125000005597 hydrazone group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000003586 protic polar solvent Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
- B01J21/18—Carbon
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/42—Platinum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invención se refiere a un proceso catalítico para preparar pirazoles que comprende la etapa de ciclar compuestos de carbonilo a,ß-insaturados sustituidos por hidrazona mediante su reacción con hidrógeno en una mezcla de reacción que comprende como componentes (a) un catalizador de hidrogenación, (b) un ácido seleccionado de ácidos de Brønsted, sales de amonio de ácidos de Brønsted y ácidos de Lewis, (c) un solvente prótico y opcionalmente (d) un solvente aprótico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16153833 | 2016-02-02 | ||
| PCT/EP2017/051524 WO2017133942A1 (en) | 2016-02-02 | 2017-01-25 | Catalytic hydrogenation process for preparing pyrazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018009453A MX2018009453A (es) | 2018-09-21 |
| MX384709B true MX384709B (es) | 2025-03-14 |
Family
ID=55304873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018009453A MX384709B (es) | 2016-02-02 | 2017-01-25 | Proceso de hidrogenación catalítico para preparar pirazoles. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10975036B2 (es) |
| EP (1) | EP3411360B1 (es) |
| JP (1) | JP6900400B2 (es) |
| KR (1) | KR102651666B1 (es) |
| CN (1) | CN108699003B (es) |
| AU (1) | AU2017216082B2 (es) |
| BR (1) | BR112018014357B8 (es) |
| CA (1) | CA3010561C (es) |
| CL (1) | CL2018002075A1 (es) |
| CO (1) | CO2018008428A2 (es) |
| DK (1) | DK3411360T3 (es) |
| ES (1) | ES2795874T3 (es) |
| IL (1) | IL260375B (es) |
| MX (1) | MX384709B (es) |
| PE (1) | PE20181539A1 (es) |
| PL (1) | PL3411360T3 (es) |
| PT (1) | PT3411360T (es) |
| RU (1) | RU2733958C2 (es) |
| UA (1) | UA124928C2 (es) |
| WO (1) | WO2017133942A1 (es) |
| ZA (1) | ZA201805742B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102531217B1 (ko) | 2014-07-31 | 2023-05-10 | 바스프 에스이 | 피라졸의 제조 방법 |
| WO2016180642A1 (en) | 2015-05-08 | 2016-11-17 | BASF Agro B.V. | A process for the preparation of terpinolene epoxide |
| WO2016180614A1 (en) | 2015-05-08 | 2016-11-17 | Basf Se | A process for the preparation of limonene-4-ol |
| PE20180327A1 (es) | 2015-05-11 | 2018-02-13 | Basf Se | Proceso para preparar 4-amino-piridazinas |
| KR20190017924A (ko) | 2016-06-15 | 2019-02-20 | 바스프 아그로 비.브이. | 4치환 알켄의 에폭시화 방법 |
| ES2877169T3 (es) | 2016-06-15 | 2021-11-16 | Basf Agro Bv | Procedimiento para la epoxidación de un alqueno tetrasustituido |
| BR112018077104A2 (pt) | 2016-07-07 | 2019-04-02 | Basf Se | compostos, processo para a preparação de compostos de fórmula i, processo para a preparação de compostos de fórmula iv e uso de compostos da fórmula i |
| ES2858699T3 (es) | 2016-11-04 | 2021-09-30 | Basf Se | Procedimiento para la purificación de pirazolpiridazinas |
| US10538493B2 (en) | 2016-11-17 | 2020-01-21 | Basf Se | Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol |
| WO2018137959A1 (en) | 2017-01-25 | 2018-08-02 | Basf Se | Process for preparation of benzylic amides |
| US11261145B2 (en) | 2017-03-20 | 2022-03-01 | Basf Se | Process for preparing bromotrichloromethane |
| US11358922B2 (en) | 2017-11-02 | 2022-06-14 | Basf Se | Process for preparing 4-chlorobenzyl propargyl ether |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007326784A (ja) * | 2006-06-06 | 2007-12-20 | Sagami Chem Res Center | １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法 |
| CA2684950A1 (en) * | 2007-04-20 | 2008-10-30 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| US20110189167A1 (en) | 2007-04-20 | 2011-08-04 | Flynn Daniel L | Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases |
| AR068063A1 (es) | 2007-08-27 | 2009-11-04 | Basf Plant Science Gmbh | Co mpuestos de pirazol para controlar plagas de invertebrados |
| WO2009068652A1 (en) * | 2007-11-30 | 2009-06-04 | Smithkline Beecham Corporation | 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators |
| EP2288597B1 (de) * | 2008-05-05 | 2014-10-29 | Basf Se | Verfahren zur herstellung von 1,3,4-substituierten pyrazolverbindungen |
| WO2010034738A2 (en) | 2008-09-24 | 2010-04-01 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
| WO2010034737A1 (en) | 2008-09-24 | 2010-04-01 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
| EP2236505A1 (de) | 2009-04-03 | 2010-10-06 | Bayer CropScience AG | Acylierte Aminopyridine und - pyridazine als Insektizide |
| AR076984A1 (es) | 2009-06-08 | 2011-07-20 | Merck Serono Sa | Derivados de pirazol oxadiazol |
| EP3498208A1 (en) | 2011-04-12 | 2019-06-19 | Thermedical, Inc. | Devices for heating fluid in fluid enhanced ablation therapy |
| CN103492378B (zh) * | 2011-04-21 | 2016-09-28 | 巴斯夫欧洲公司 | 杀虫吡唑化合物 |
| JO3407B1 (ar) * | 2012-05-31 | 2019-10-20 | Eisai R&D Man Co Ltd | مركبات رباعي هيدرو بيرازولو بيريميدين |
| EP2671873A1 (en) * | 2012-06-06 | 2013-12-11 | Solvay Sa | Method for the cyclization of hydrazinoacrylic acid derivatives |
| WO2013189801A1 (en) * | 2012-06-20 | 2013-12-27 | Basf Se | Pyrazole compound and pesticidal mixtures comprising a pyrazole compound |
| WO2014089364A1 (en) | 2012-12-06 | 2014-06-12 | Quanticel Pharmaceuticals, Inc | Histone demethylase inhibitors |
| KR102531217B1 (ko) * | 2014-07-31 | 2023-05-10 | 바스프 에스이 | 피라졸의 제조 방법 |
| PE20180327A1 (es) | 2015-05-11 | 2018-02-13 | Basf Se | Proceso para preparar 4-amino-piridazinas |
-
2017
- 2017-01-25 ES ES17701485T patent/ES2795874T3/es active Active
- 2017-01-25 PT PT177014859T patent/PT3411360T/pt unknown
- 2017-01-25 US US16/074,537 patent/US10975036B2/en active Active
- 2017-01-25 AU AU2017216082A patent/AU2017216082B2/en active Active
- 2017-01-25 CA CA3010561A patent/CA3010561C/en active Active
- 2017-01-25 KR KR1020187025347A patent/KR102651666B1/ko active Active
- 2017-01-25 WO PCT/EP2017/051524 patent/WO2017133942A1/en not_active Ceased
- 2017-01-25 RU RU2018130339A patent/RU2733958C2/ru active
- 2017-01-25 PL PL17701485T patent/PL3411360T3/pl unknown
- 2017-01-25 BR BR112018014357A patent/BR112018014357B8/pt active IP Right Grant
- 2017-01-25 EP EP17701485.9A patent/EP3411360B1/en active Active
- 2017-01-25 DK DK17701485.9T patent/DK3411360T3/da active
- 2017-01-25 UA UAA201808830A patent/UA124928C2/uk unknown
- 2017-01-25 CN CN201780009304.6A patent/CN108699003B/zh active Active
- 2017-01-25 MX MX2018009453A patent/MX384709B/es unknown
- 2017-01-25 PE PE2018001381A patent/PE20181539A1/es unknown
- 2017-01-25 JP JP2018558485A patent/JP6900400B2/ja active Active
-
2018
- 2018-07-02 IL IL260375A patent/IL260375B/en active IP Right Grant
- 2018-08-02 CL CL2018002075A patent/CL2018002075A1/es unknown
- 2018-08-10 CO CONC2018/0008428A patent/CO2018008428A2/es unknown
- 2018-08-28 ZA ZA201805742A patent/ZA201805742B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3411360A1 (en) | 2018-12-12 |
| PT3411360T (pt) | 2020-06-01 |
| US20190055200A1 (en) | 2019-02-21 |
| CA3010561A1 (en) | 2017-08-10 |
| PL3411360T3 (pl) | 2020-08-24 |
| WO2017133942A1 (en) | 2017-08-10 |
| PE20181539A1 (es) | 2018-09-26 |
| BR112018014357A2 (pt) | 2018-12-18 |
| RU2733958C2 (ru) | 2020-10-08 |
| AU2017216082B2 (en) | 2020-12-03 |
| RU2018130339A (ru) | 2020-03-04 |
| JP2019504883A (ja) | 2019-02-21 |
| CN108699003B (zh) | 2023-02-03 |
| KR102651666B1 (ko) | 2024-03-26 |
| AU2017216082A1 (en) | 2018-07-26 |
| ZA201805742B (en) | 2019-11-27 |
| CL2018002075A1 (es) | 2018-09-14 |
| UA124928C2 (uk) | 2021-12-15 |
| BR112018014357B1 (pt) | 2022-08-16 |
| CN108699003A (zh) | 2018-10-23 |
| CO2018008428A2 (es) | 2018-08-21 |
| IL260375B (en) | 2021-03-25 |
| CA3010561C (en) | 2024-04-16 |
| JP6900400B2 (ja) | 2021-07-07 |
| RU2018130339A3 (es) | 2020-03-19 |
| BR112018014357B8 (pt) | 2022-09-06 |
| DK3411360T3 (da) | 2020-06-08 |
| MX2018009453A (es) | 2018-09-21 |
| KR20180104743A (ko) | 2018-09-21 |
| EP3411360B1 (en) | 2020-03-11 |
| US10975036B2 (en) | 2021-04-13 |
| ES2795874T3 (es) | 2020-11-25 |
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