CL2018002075A1 - Proceso de hidrogenación catalítico para preparar pirazoles - Google Patents

Proceso de hidrogenación catalítico para preparar pirazoles

Info

Publication number
CL2018002075A1
CL2018002075A1 CL2018002075A CL2018002075A CL2018002075A1 CL 2018002075 A1 CL2018002075 A1 CL 2018002075A1 CL 2018002075 A CL2018002075 A CL 2018002075A CL 2018002075 A CL2018002075 A CL 2018002075A CL 2018002075 A1 CL2018002075 A1 CL 2018002075A1
Authority
CL
Chile
Prior art keywords
catalytic hydrogenation
hydrogenation process
acids
pyrazoles
prepare
Prior art date
Application number
CL2018002075A
Other languages
English (en)
Inventor
Birgit Gockel
Eric George Klauber
Michael Rack
Sebastian Soergel
Roland Goetz
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of CL2018002075A1 publication Critical patent/CL2018002075A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/18—Carbon
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/42—Platinum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UN PROCESO CATALÍTICO PARA PREPARAR PIRAZOLES QUE COMPRENDE LA ETAPA DE CICLAR COMPUESTOS DE CARBONILO A,ß-INSATURADOS SUSTITUIDOS POR HIDRAZONA MEDIANTE SU REACCIÓN CON HIDRÓGENO EN UNA MEZCLA DE REACCIÓN QUE COMPRENDE COMO COMPONENTES (A) UN CATALIZADOR DE HIDROGENACIÓN, (B) UN ÁCIDO SELECCIONADO DE ÁCIDOS DE BRØNSTED, SALES DE AMONIO DE ÁCIDOS DE BRØNSTED Y ÁCIDOS DE LEWIS, (C) UN SOLVENTE PRÓTICO Y OPCIONALMENTE (D) UN SOLVENTE APRÓTICO.
CL2018002075A 2016-02-02 2018-08-02 Proceso de hidrogenación catalítico para preparar pirazoles CL2018002075A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16153833 2016-02-02

Publications (1)

Publication Number Publication Date
CL2018002075A1 true CL2018002075A1 (es) 2018-09-14

Family

ID=55304873

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002075A CL2018002075A1 (es) 2016-02-02 2018-08-02 Proceso de hidrogenación catalítico para preparar pirazoles

Country Status (20)

Country Link
US (1) US10975036B2 (es)
EP (1) EP3411360B1 (es)
JP (1) JP6900400B2 (es)
KR (1) KR102651666B1 (es)
CN (1) CN108699003B (es)
AU (1) AU2017216082B2 (es)
BR (1) BR112018014357B8 (es)
CA (1) CA3010561C (es)
CL (1) CL2018002075A1 (es)
CO (1) CO2018008428A2 (es)
DK (1) DK3411360T3 (es)
ES (1) ES2795874T3 (es)
IL (1) IL260375B (es)
MX (1) MX2018009453A (es)
PE (1) PE20181539A1 (es)
PL (1) PL3411360T3 (es)
PT (1) PT3411360T (es)
RU (1) RU2733958C2 (es)
WO (1) WO2017133942A1 (es)
ZA (1) ZA201805742B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2954212C (en) 2014-07-31 2023-09-19 Basf Se Process for preparing pyrazoles
CN107635982A (zh) 2015-05-08 2018-01-26 巴斯夫农业公司 制备萜品油烯环氧化物的方法
US10538470B2 (en) 2015-05-08 2020-01-21 BASF Agro B.V. Process for the preparation of limonene-4-ol
EP3872073A1 (en) 2015-05-11 2021-09-01 Basf Se Process for preparing 4-amino-pyridazines
AU2017284971B2 (en) 2016-06-15 2021-01-21 BASF Agro B.V. Process for the epoxidation of a tetrasubstituted alkene
AU2017286055B2 (en) 2016-06-15 2021-07-01 BASF Agro B.V. Process for the epoxidation of a tetrasubstituted alkene
BR112018077104A2 (pt) 2016-07-07 2019-04-02 Basf Se compostos, processo para a preparação de compostos de fórmula i, processo para a preparação de compostos de fórmula iv e uso de compostos da fórmula i
LT3535257T (lt) 2016-11-04 2021-02-25 Basf Se Pirazolpiridazinų gryninimo būdas
US10538493B2 (en) 2016-11-17 2020-01-21 Basf Se Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol
BR112019015231A2 (pt) 2017-01-25 2020-04-14 Basf Se processos para a preparação de compostos e compostos
EP3601202B1 (en) 2017-03-20 2023-05-10 Basf Se Process for preparing bromotrichloromethane
US11358922B2 (en) 2017-11-02 2022-06-14 Basf Se Process for preparing 4-chlorobenzyl propargyl ether

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007326784A (ja) 2006-06-06 2007-12-20 Sagami Chem Res Center １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
US20110189167A1 (en) 2007-04-20 2011-08-04 Flynn Daniel L Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
EP2481736A1 (en) * 2007-04-20 2012-08-01 Deciphera Pharmaceuticals, LLC. Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
RU2516290C2 (ru) 2007-08-27 2014-05-20 Басф Се Пиразольные соединения и их использование в способе борьбы с беспозвоночными вредителями, в способе защиты материала размножения растений, в способе лечения или защиты животных от инвазии или инфицирования, в материале размножения растений и сельскохозяйственные композиции, содержащие пиразольные соединения
WO2009068652A1 (en) * 2007-11-30 2009-06-04 Smithkline Beecham Corporation 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators
DK2288597T3 (en) * 2008-05-05 2015-01-26 Basf Se PROCESS FOR THE PREPARATION OF 1,3,4-SUBSTITUTED pyrazole
CN104211688B (zh) * 2008-09-24 2016-04-13 巴斯夫欧洲公司 防治无脊椎动物害虫的吡唑化合物
WO2010034738A2 (en) 2008-09-24 2010-04-01 Basf Se Pyrazole compounds for controlling invertebrate pests
EP2236505A1 (de) 2009-04-03 2010-10-06 Bayer CropScience AG Acylierte Aminopyridine und - pyridazine als Insektizide
AR076984A1 (es) 2009-06-08 2011-07-20 Merck Serono Sa Derivados de pirazol oxadiazol
WO2012142217A1 (en) 2011-04-12 2012-10-18 Thermedical, Inc. Devices and methods for remote temperature monitoring in fluid enhanced ablation therapy
BR112013024708B1 (pt) * 2011-04-21 2018-10-09 Basf Se compostos de pirazol,composições, métodos para combater ou controlar pragas invertebradas e para proteger plantas em crescimento, processo para proteger sementes e uso dos compostos
JO3407B1 (ar) * 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
EP2671873A1 (en) * 2012-06-06 2013-12-11 Solvay Sa Method for the cyclization of hydrazinoacrylic acid derivatives
AU2013279540B2 (en) 2012-06-20 2017-07-13 Basf Se Pyrazole compound and pesticidal mixtures comprising a pyrazole compound
US9604961B2 (en) 2012-12-06 2017-03-28 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
CA2954212C (en) 2014-07-31 2023-09-19 Basf Se Process for preparing pyrazoles
EP3872073A1 (en) 2015-05-11 2021-09-01 Basf Se Process for preparing 4-amino-pyridazines

Also Published As

Publication number Publication date
ES2795874T3 (es) 2020-11-25
RU2733958C2 (ru) 2020-10-08
DK3411360T3 (da) 2020-06-08
CN108699003B (zh) 2023-02-03
US10975036B2 (en) 2021-04-13
CA3010561A1 (en) 2017-08-10
RU2018130339A3 (es) 2020-03-19
BR112018014357B1 (pt) 2022-08-16
PE20181539A1 (es) 2018-09-26
ZA201805742B (en) 2019-11-27
PL3411360T3 (pl) 2020-08-24
KR102651666B1 (ko) 2024-03-26
EP3411360A1 (en) 2018-12-12
JP6900400B2 (ja) 2021-07-07
RU2018130339A (ru) 2020-03-04
US20190055200A1 (en) 2019-02-21
IL260375B (en) 2021-03-25
PT3411360T (pt) 2020-06-01
MX2018009453A (es) 2018-09-21
CN108699003A (zh) 2018-10-23
AU2017216082A1 (en) 2018-07-26
CO2018008428A2 (es) 2018-08-21
CA3010561C (en) 2024-04-16
EP3411360B1 (en) 2020-03-11
BR112018014357A2 (pt) 2018-12-18
JP2019504883A (ja) 2019-02-21
BR112018014357B8 (pt) 2022-09-06
AU2017216082B2 (en) 2020-12-03
KR20180104743A (ko) 2018-09-21
WO2017133942A1 (en) 2017-08-10

Similar Documents

Publication Publication Date Title
CL2018002075A1 (es) Proceso de hidrogenación catalítico para preparar pirazoles
CL2016003324A1 (es) Construcciones de anticuerpos multiespecificos.
BR112018015336A2 (pt) processo de preparação de terpineno-4-ol e uso de éster de ácido carboxílico como solvente
CO2017011957A2 (es) Variantes de alfa-amilasa y polinucleótidos que codifican las mismas
CU24466B1 (es) Compuestos derivados de d-fenilalanina-n-sustituido con biciclos aromáticos, método de preparación de las mismas y composiciones farmacéuticas que los contienen
CL2017003163A1 (es) Nuevos derivados aminoácido, un proceso para su preparación y composiciones farmacéuticas que los contienen
CR20170564A (es) Nuevos derivados hidroxiéster, un proceso para su preparación y composiciones farmacéuticas que los contienen
MX365892B (es) Procedimiento para la preparacion de un material zeolitico.
CL2016000919A1 (es) Método para preparar un portador esférico de un catalizador para la polimerización de olefinas; portador esférico; proceso para preparar una composición solida; composición solida; componente catalizador; método para preparar un componente catalizador; catalizador para la polimerización de olefinas; uso del catalizador; y método para la polimerización de olefina(s).
PH12015501960B1 (en) Processes for the preparation of an apoptosis-inducing agent
BR112014019909A8 (pt) Processo para produção de compostos úteis como antagonistas do receptor de orexina-2
CY1121304T1 (el) Μεθοδος καθαρισμου σαπωνινων
BR112018010229A2 (pt) sistema catalisador e processo para a produção de glicóis
UY36327A (es) Compuestos de 1-alquil-6-oxo-1,6-dihidropiridin-3-ilo y sus usos en el tratamiento de una afección mediada por el receptor de glucocorticoides
CL2018000756A1 (es) Métodos moleculares de aseguramiento de la calidad para su uso en la secuenciación
BR112017006552A2 (pt) composições e métodos para inibir a atividade biológica de biomoléculas solúveis
MX2016011476A (es) Catalizadores de rutenio-fenol para reacciones de hidrogenacion por transferencia.
MX2020004869A (es) Metodo para preparar derivado de benzofurano.
GB2550677A (en) Process of removing heat
AR101931A1 (es) Líquido iónico, aducto y sus métodos
BR112017004029A2 (pt) produção de poliolefinas com catalisadores à base de cromo
CL2017002255A1 (es) Procesos para preparar fluorocetólidos.
BR112018010230A2 (pt) sistema catalisador e processo para a produção de glicóis
BR112015007737A8 (pt) complexo oxo-nitrogenado de cobalto, sistema catalítico compreendendo o dito complexo oxo-nitrogenado, processo para a (co)polimerização de dienos conjugados e polibutadieno obtido pelo dito processo”.
BR112016030604B8 (pt) Processo para preparação de ácidos 3- hidroxipicolínicos