MX382656B - 3-oxo-3-(arilamino) propanoatos, proceso para su preparación y su uso en la preparación de pirrolidinonas. - Google Patents
3-oxo-3-(arilamino) propanoatos, proceso para su preparación y su uso en la preparación de pirrolidinonas.Info
- Publication number
- MX382656B MX382656B MX2017007087A MX2017007087A MX382656B MX 382656 B MX382656 B MX 382656B MX 2017007087 A MX2017007087 A MX 2017007087A MX 2017007087 A MX2017007087 A MX 2017007087A MX 382656 B MX382656 B MX 382656B
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- formula
- compound
- sup
- propanoates
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000004040 pyrrolidinones Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B31/00—Reduction in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088971P | 2014-12-08 | 2014-12-08 | |
| PCT/US2015/063101 WO2016094117A1 (en) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017007087A MX2017007087A (es) | 2017-09-05 |
| MX382656B true MX382656B (es) | 2025-03-13 |
Family
ID=54782892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017007087A MX382656B (es) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arilamino) propanoatos, proceso para su preparación y su uso en la preparación de pirrolidinonas. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10227286B2 (https=) |
| EP (1) | EP3230264B1 (https=) |
| JP (1) | JP6611816B2 (https=) |
| KR (1) | KR102542215B1 (https=) |
| CN (1) | CN107001260B (https=) |
| AR (1) | AR102939A1 (https=) |
| AU (1) | AU2015361018B2 (https=) |
| BR (1) | BR112017009701B1 (https=) |
| ES (1) | ES2759267T3 (https=) |
| HU (1) | HUE047582T2 (https=) |
| IL (1) | IL252637A (https=) |
| MX (1) | MX382656B (https=) |
| PL (1) | PL3230264T3 (https=) |
| RU (1) | RU2712831C2 (https=) |
| SG (1) | SG11201702924WA (https=) |
| TW (1) | TWI694982B (https=) |
| WO (1) | WO2016094117A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2016007259A (es) | 2013-12-03 | 2016-08-04 | Du Pont | Pirrolidinonas como herbicidas. |
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| US9944602B2 (en) | 2014-07-02 | 2018-04-17 | E. I. Du Pont De Nemours And Company | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
| PL3294743T3 (pl) | 2015-05-12 | 2020-03-31 | Fmc Corporation | Podstawione arylem związki bicykliczne jako środki chwastobójcze |
| WO2016196019A1 (en) | 2015-05-29 | 2016-12-08 | E I Du Pont De Nemours And Company | Substituted cyclic amides as herbicides |
| CN107709310B (zh) | 2015-06-02 | 2021-09-24 | Fmc公司 | 取代的环酰胺及其作为除草剂的用途 |
| CN108137512B (zh) | 2015-07-31 | 2022-05-31 | Fmc公司 | 用作除草剂的环状n-酰胺化合物 |
| GB201617050D0 (en) | 2016-10-07 | 2016-11-23 | Syngenta Participations Ag | Herbicidal mixtures |
| CA3047724A1 (en) | 2016-12-21 | 2018-06-28 | Fmc Corporation | Nitrone herbicides |
| WO2018175231A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Herbicidal mixture, composition and method |
| CA3057297A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Pyrrolidinones and a process to prepare them |
| WO2018177836A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | N-cyclopropyl-2-oxopyrrolidin-3-carboxamid-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| WO2018177837A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | 4-cyclopentyl- und 4-cyclopropyl-2-oxopyrrolidin-3-carboxami d-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| WO2019025156A1 (de) | 2017-08-03 | 2019-02-07 | Bayer Aktiengesellschaft | Substituierte pyrrolidinone sowie deren salze und ihre verwendung als herbizide wirkstoffe |
| GB201819747D0 (en) | 2018-12-04 | 2019-01-16 | Syngenta Participations Ag | Herbicidal compositions |
| WO2020164924A1 (en) | 2019-02-15 | 2020-08-20 | Syngenta Crop Protection Ag | Herbicidal compositions |
| EP4508980A3 (en) | 2021-12-15 | 2025-07-16 | Adama Agan Ltd. | Compounds useful for the preparation of various agrochemicals and markers thereof |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1262277B (de) | 1962-12-05 | 1968-03-07 | Basf Ag | Verfahren zur Herstellung von Pyrrolidonen |
| US3741989A (en) | 1970-10-27 | 1973-06-26 | Abbott Lab | Lactonic acetals |
| JPS5356288A (en) | 1976-10-30 | 1978-05-22 | Matsushita Electric Works Ltd | Preparation of phenolic resin |
| JPS5488114A (en) | 1977-12-26 | 1979-07-13 | Fuji Photo Film Co Ltd | Manufacturing device for photograph seal |
| US4594094A (en) | 1983-04-04 | 1986-06-10 | Shell Oil Company | Oxacycloalkane-alpha-(thio)carboxylic acid derivatives and use as plant growth regulators and herbicides |
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| JP3487669B2 (ja) | 1995-03-28 | 2004-01-19 | 積水化学工業株式会社 | 不飽和ポリエステル樹脂組成物 |
| AU5195999A (en) | 1998-08-11 | 2000-03-06 | Takeda Chemical Industries Ltd. | Cyclic amide compounds, process for producing the same, intermediates thereof and herbicides |
| US20040242671A1 (en) | 2001-10-08 | 2004-12-02 | Renee Grimee | Use of 2-oxo-1-pyrrolidine derivatives for the preparation of a drug |
| DE60333762D1 (de) | 2002-08-23 | 2010-09-23 | Novartis Vaccines & Diagnostic | Pyrrolverbindungen als glykogen synthase kinase 3 inhibitoren |
| WO2004037787A1 (de) * | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidin-2-on-3-carboxamide |
| AU2003277721A1 (en) | 2002-11-15 | 2004-06-15 | In Kwon Chung | Beta-nitrostyrene compound and telomerase inhibitor having an anticancer activity |
| US7205318B2 (en) | 2003-03-18 | 2007-04-17 | Bristol-Myers Squibb Company | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors |
| JP2008528625A (ja) | 2005-01-28 | 2008-07-31 | アイアールエム・リミテッド・ライアビリティ・カンパニー | アリールピロリドン類の合成 |
| US20070123508A1 (en) | 2005-05-27 | 2007-05-31 | Roger Olsson | PAR2-modulating compounds and their use |
| WO2007066828A1 (ja) | 2005-12-09 | 2007-06-14 | Sumitomo Chemical Company, Limited | 光学活性な４－アミノ－３－置換フェニルブタン酸の製造方法 |
| ES2304220B1 (es) | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| EP2065380A1 (en) | 2007-08-22 | 2009-06-03 | F.Hoffmann-La Roche Ag | Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer |
| CN101412711A (zh) | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | 氨基甲酸酯类衍生物及其在医药上的应用 |
| CN102137841B (zh) | 2008-09-02 | 2014-05-14 | 日产化学工业株式会社 | 邻位取代卤代烷基磺酰苯胺衍生物及除草剂 |
| JPWO2010053165A1 (ja) | 2008-11-04 | 2012-04-05 | 帝人ファーマ株式会社 | ビタミンｄ３ラクタム誘導体 |
| BRPI1007995A2 (pt) * | 2009-02-23 | 2019-09-24 | Hoffmann La Roche | orto-aminoamidas para o tratamento de cãncer. |
| CN101747252A (zh) * | 2009-12-28 | 2010-06-23 | 嘉兴宜博生物医药科技有限公司 | R构诺普利兰的合成方法 |
| US9150591B2 (en) | 2010-08-10 | 2015-10-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| EP2613782B1 (en) | 2010-09-01 | 2016-11-02 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as erk inhibitors |
| CA2835835C (en) | 2011-05-13 | 2019-04-02 | Array Biopharma Inc. | Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as trka kinase inhibitors |
| CN102531918B (zh) | 2012-01-18 | 2013-10-02 | 安阳工学院 | 一种对映纯对称反式二烷基环己胺的合成方法 |
| KR20130142477A (ko) | 2012-06-19 | 2013-12-30 | 순천향대학교 산학협력단 | 키랄 나이트로사이클로프로판 유도체의 제조방법 |
| WO2014065413A1 (ja) * | 2012-10-26 | 2014-05-01 | 日本たばこ産業株式会社 | トリアゾール・イソオキサゾール化合物およびその医薬用途 |
| MX2016007259A (es) * | 2013-12-03 | 2016-08-04 | Du Pont | Pirrolidinonas como herbicidas. |
| GB201321743D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| RU2555370C1 (ru) | 2014-02-12 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный технический университет" | Способ энантиоселективного синтеза диэтил[3-метил-(1s)-(нитрометил)бутил]малоната формулы i |
| US9944602B2 (en) | 2014-07-02 | 2018-04-17 | E. I. Du Pont De Nemours And Company | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
| PL3294743T3 (pl) | 2015-05-12 | 2020-03-31 | Fmc Corporation | Podstawione arylem związki bicykliczne jako środki chwastobójcze |
| WO2016196019A1 (en) | 2015-05-29 | 2016-12-08 | E I Du Pont De Nemours And Company | Substituted cyclic amides as herbicides |
| CN107709310B (zh) * | 2015-06-02 | 2021-09-24 | Fmc公司 | 取代的环酰胺及其作为除草剂的用途 |
| CN108137512B (zh) | 2015-07-31 | 2022-05-31 | Fmc公司 | 用作除草剂的环状n-酰胺化合物 |
| CA3047724A1 (en) | 2016-12-21 | 2018-06-28 | Fmc Corporation | Nitrone herbicides |
| WO2018175231A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Herbicidal mixture, composition and method |
| CA3057297A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Pyrrolidinones and a process to prepare them |
-
2015
- 2015-12-01 EP EP15805092.2A patent/EP3230264B1/en active Active
- 2015-12-01 WO PCT/US2015/063101 patent/WO2016094117A1/en not_active Ceased
- 2015-12-01 ES ES15805092T patent/ES2759267T3/es active Active
- 2015-12-01 RU RU2017123114A patent/RU2712831C2/ru active
- 2015-12-01 KR KR1020177018406A patent/KR102542215B1/ko active Active
- 2015-12-01 BR BR112017009701-0A patent/BR112017009701B1/pt active IP Right Grant
- 2015-12-01 JP JP2017548361A patent/JP6611816B2/ja active Active
- 2015-12-01 MX MX2017007087A patent/MX382656B/es unknown
- 2015-12-01 SG SG11201702924WA patent/SG11201702924WA/en unknown
- 2015-12-01 PL PL15805092T patent/PL3230264T3/pl unknown
- 2015-12-01 HU HUE15805092A patent/HUE047582T2/hu unknown
- 2015-12-01 AU AU2015361018A patent/AU2015361018B2/en active Active
- 2015-12-01 CN CN201580065080.1A patent/CN107001260B/zh active Active
- 2015-12-01 US US15/533,448 patent/US10227286B2/en active Active
- 2015-12-04 AR ARP150103996A patent/AR102939A1/es active IP Right Grant
- 2015-12-04 TW TW104140692A patent/TWI694982B/zh active
-
2017
- 2017-06-04 IL IL252637A patent/IL252637A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| RU2017123114A3 (https=) | 2019-07-17 |
| RU2017123114A (ru) | 2019-01-11 |
| PL3230264T3 (pl) | 2020-03-31 |
| CN107001260B (zh) | 2020-11-10 |
| JP2017538785A (ja) | 2017-12-28 |
| BR112017009701B1 (pt) | 2021-09-08 |
| US10227286B2 (en) | 2019-03-12 |
| BR112017009701A2 (pt) | 2018-02-20 |
| US20180057442A1 (en) | 2018-03-01 |
| ES2759267T3 (es) | 2020-05-08 |
| EP3230264B1 (en) | 2019-09-11 |
| HUE047582T2 (hu) | 2020-05-28 |
| RU2712831C2 (ru) | 2020-02-03 |
| MX2017007087A (es) | 2017-09-05 |
| KR102542215B1 (ko) | 2023-06-12 |
| TW201632497A (zh) | 2016-09-16 |
| IL252637A0 (en) | 2017-07-31 |
| WO2016094117A1 (en) | 2016-06-16 |
| AR102939A1 (es) | 2017-04-05 |
| EP3230264A1 (en) | 2017-10-18 |
| KR20170090491A (ko) | 2017-08-07 |
| SG11201702924WA (en) | 2017-05-30 |
| IL252637A (en) | 2017-11-30 |
| AU2015361018A1 (en) | 2017-04-27 |
| TWI694982B (zh) | 2020-06-01 |
| AU2015361018B2 (en) | 2020-01-16 |
| CN107001260A (zh) | 2017-08-01 |
| JP6611816B2 (ja) | 2019-11-27 |
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