MX382156B - Sondas para formar imagenes de proteina de huntingtina. - Google Patents
Sondas para formar imagenes de proteina de huntingtina.Info
- Publication number
- MX382156B MX382156B MX2018002338A MX2018002338A MX382156B MX 382156 B MX382156 B MX 382156B MX 2018002338 A MX2018002338 A MX 2018002338A MX 2018002338 A MX2018002338 A MX 2018002338A MX 382156 B MX382156 B MX 382156B
- Authority
- MX
- Mexico
- Prior art keywords
- probes
- huntingtin protein
- imaging
- imaging huntingtin
- formula
- Prior art date
Links
- 102000016252 Huntingtin Human genes 0.000 title 1
- 108050004784 Huntingtin Proteins 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nuclear Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562211118P | 2015-08-28 | 2015-08-28 | |
| PCT/US2016/049112 WO2017040336A1 (en) | 2015-08-28 | 2016-08-26 | Probes for imaging huntingtin protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018002338A MX2018002338A (es) | 2018-07-06 |
| MX382156B true MX382156B (es) | 2025-03-13 |
Family
ID=58103449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018002338A MX382156B (es) | 2015-08-28 | 2016-08-26 | Sondas para formar imagenes de proteina de huntingtina. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10137211B2 (enExample) |
| EP (1) | EP3340796B1 (enExample) |
| JP (1) | JP6944929B2 (enExample) |
| CN (1) | CN108135172B (enExample) |
| AU (1) | AU2016315648B2 (enExample) |
| BR (1) | BR112018003331B1 (enExample) |
| CA (1) | CA2995847C (enExample) |
| DK (1) | DK3340796T3 (enExample) |
| ES (1) | ES2885053T3 (enExample) |
| HR (1) | HRP20211156T1 (enExample) |
| HU (1) | HUE056509T2 (enExample) |
| IL (1) | IL257537B (enExample) |
| MX (1) | MX382156B (enExample) |
| PL (1) | PL3340796T3 (enExample) |
| PT (1) | PT3340796T (enExample) |
| RU (1) | RU2721419C2 (enExample) |
| SI (1) | SI3340796T1 (enExample) |
| WO (1) | WO2017040336A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3186233T3 (pl) | 2014-08-29 | 2022-02-28 | Chdi Foundation, Inc. | Sondy do obrazowania białka huntingtyny |
| ES2818107T3 (es) | 2014-08-29 | 2021-04-09 | Chdi Foundation Inc | Sondas para obtener imágenes de la proteína huntingtina |
| WO2016033440A1 (en) | 2014-08-29 | 2016-03-03 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
| ES2841746T3 (es) | 2014-08-29 | 2021-07-09 | Chdi Foundation Inc | Sondas para la imagen de la proteína de Huntington |
| HRP20211156T1 (hr) | 2015-08-28 | 2021-12-24 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
| US20210069403A1 (en) * | 2018-02-08 | 2021-03-11 | Phraxis Inc. | One piece anastomotic connector |
| JP7619952B2 (ja) | 2019-02-25 | 2025-01-22 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | 変異型ハンチンチンタンパク質を標的とするための化合物及びその使用 |
| BR112022025238A2 (pt) * | 2020-06-11 | 2023-02-14 | Chdi Foundation Inc | Compostos heterocíclicos e agentes de imageamento para formar imagem da proteína huntingtina |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0571253T3 (da) * | 1992-05-19 | 1999-07-19 | Adir | Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning |
| AU2241400A (en) * | 1999-04-06 | 2000-10-12 | Yamanouchi Pharmaceutical Co., Ltd. | Novel thiazolobenzoimidazole derivative |
| JP2000351782A (ja) * | 1999-04-06 | 2000-12-19 | Yamanouchi Pharmaceut Co Ltd | メタボトロピックグルタメート受容体作用薬及び新規チアゾロベンゾイミダゾール誘導体 |
| UY27003A1 (es) * | 2000-11-06 | 2002-07-31 | Schering Ag | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer |
| EP1684762A4 (en) * | 2003-11-13 | 2009-06-17 | Ambit Biosciences Corp | UREA DERIVATIVES AS MODULATORS OF KINASE |
| TW201018678A (en) * | 2006-01-27 | 2010-05-16 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| FR2919610B1 (fr) * | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
| WO2010011964A2 (en) * | 2008-07-24 | 2010-01-28 | Siemens Medical Solutions Usa, Inc. | Imaging agents useful for identifying ad pathology |
| EP2218464A1 (en) * | 2009-02-11 | 2010-08-18 | Technische Universität München | Compounds for non-invasive measurement of aggregates of amyloid peptides |
| WO2010111303A2 (en) * | 2009-03-23 | 2010-09-30 | Siemens Medical Solutions Usa, Inc. | Imaging agents for detecting neurological disorders |
| AU2013290080A1 (en) | 2012-07-11 | 2015-01-29 | Nimbus Iris, Inc. | IRAK inhibitors and uses thereof |
| US9902702B2 (en) * | 2014-07-15 | 2018-02-27 | Bristol-Myers Squibb Company | Spirocycloheptanes as inhibitors of rock |
| PL3186233T3 (pl) | 2014-08-29 | 2022-02-28 | Chdi Foundation, Inc. | Sondy do obrazowania białka huntingtyny |
| ES2818107T3 (es) | 2014-08-29 | 2021-04-09 | Chdi Foundation Inc | Sondas para obtener imágenes de la proteína huntingtina |
| WO2016033440A1 (en) | 2014-08-29 | 2016-03-03 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
| ES2841746T3 (es) | 2014-08-29 | 2021-07-09 | Chdi Foundation Inc | Sondas para la imagen de la proteína de Huntington |
| HRP20211156T1 (hr) | 2015-08-28 | 2021-12-24 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
-
2016
- 2016-08-26 HR HRP20211156TT patent/HRP20211156T1/hr unknown
- 2016-08-26 MX MX2018002338A patent/MX382156B/es unknown
- 2016-08-26 AU AU2016315648A patent/AU2016315648B2/en active Active
- 2016-08-26 CA CA2995847A patent/CA2995847C/en active Active
- 2016-08-26 PT PT168427151T patent/PT3340796T/pt unknown
- 2016-08-26 SI SI201631285T patent/SI3340796T1/sl unknown
- 2016-08-26 WO PCT/US2016/049112 patent/WO2017040336A1/en not_active Ceased
- 2016-08-26 PL PL16842715T patent/PL3340796T3/pl unknown
- 2016-08-26 DK DK16842715.1T patent/DK3340796T3/da active
- 2016-08-26 BR BR112018003331-6A patent/BR112018003331B1/pt active IP Right Grant
- 2016-08-26 RU RU2018110055A patent/RU2721419C2/ru active
- 2016-08-26 EP EP16842715.1A patent/EP3340796B1/en active Active
- 2016-08-26 JP JP2018510377A patent/JP6944929B2/ja active Active
- 2016-08-26 ES ES16842715T patent/ES2885053T3/es active Active
- 2016-08-26 CN CN201680059497.1A patent/CN108135172B/zh active Active
- 2016-08-26 US US15/249,223 patent/US10137211B2/en active Active
- 2016-08-26 HU HUE16842715A patent/HUE056509T2/hu unknown
-
2018
- 2018-02-14 IL IL257537A patent/IL257537B/en active IP Right Grant
- 2018-10-26 US US16/172,425 patent/US10765764B2/en active Active
-
2020
- 2020-08-06 US US16/987,277 patent/US11344637B2/en active Active
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