SG11201701580XA - Probes for imaging huntingtin protein - Google Patents
Probes for imaging huntingtin proteinInfo
- Publication number
- SG11201701580XA SG11201701580XA SG11201701580XA SG11201701580XA SG11201701580XA SG 11201701580X A SG11201701580X A SG 11201701580XA SG 11201701580X A SG11201701580X A SG 11201701580XA SG 11201701580X A SG11201701580X A SG 11201701580XA SG 11201701580X A SG11201701580X A SG 11201701580XA
- Authority
- SG
- Singapore
- Prior art keywords
- probes
- huntingtin protein
- imaging
- imaging huntingtin
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K51/0419—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462043617P | 2014-08-29 | 2014-08-29 | |
PCT/US2015/047427 WO2016033460A1 (en) | 2014-08-29 | 2015-08-28 | Probes for imaging huntingtin protein |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701580XA true SG11201701580XA (en) | 2017-03-30 |
Family
ID=55400659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201701580XA SG11201701580XA (en) | 2014-08-29 | 2015-08-28 | Probes for imaging huntingtin protein |
Country Status (14)
Country | Link |
---|---|
US (1) | US10907197B2 (en) |
EP (1) | EP3190888B1 (en) |
JP (1) | JP2017528520A (en) |
KR (1) | KR20170047341A (en) |
CN (1) | CN107105655A (en) |
AU (2) | AU2015308709B2 (en) |
BR (1) | BR112017004134A2 (en) |
CA (1) | CA2959505A1 (en) |
EA (1) | EA201790408A1 (en) |
ES (1) | ES2818107T3 (en) |
IL (1) | IL250804A0 (en) |
MX (1) | MX2017002705A (en) |
SG (1) | SG11201701580XA (en) |
WO (1) | WO2016033460A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2959531C (en) | 2014-08-29 | 2023-01-10 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
PL3186233T3 (en) | 2014-08-29 | 2022-02-28 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
PL3197277T3 (en) | 2014-08-29 | 2022-04-04 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
MX2018002338A (en) | 2015-08-28 | 2018-07-06 | Chdi Foundation Inc | Probes for imaging huntingtin protein. |
CN106632002A (en) * | 2016-09-28 | 2017-05-10 | 贵州大学 | Preparation technology of etoricoxib and reference substance 5-chloro-3-(4-(methyl sulphonyl)phenyl)-2,3-bipyridine of etoricoxib |
GB201617339D0 (en) | 2016-10-12 | 2016-11-23 | Lytix Biopharma As | Therapeutic compounds |
CN108178764A (en) * | 2018-01-09 | 2018-06-19 | 天津科技大学 | Furans simultaneously [2,3-b] pyridine compounds and their and the synthetic method without metal catalytic |
WO2020176424A1 (en) | 2019-02-25 | 2020-09-03 | Chdi Foundation, Inc. | Compounds for targeting mutant huntingtin protein and uses thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1367836A (en) * | 1918-04-29 | 1921-02-08 | Int Precipitation Co | Process for obtaining chlorids of potassium or other metals |
US3985755A (en) * | 1972-06-02 | 1976-10-12 | E. R. Squibb & Sons, Inc. | Pyridine containing isothiocyanobenzoxazoles |
FR2524468B1 (en) * | 1982-04-06 | 1985-10-18 | Sandoz Sa | NOVEL CONDENSED THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS |
JPS60146877A (en) * | 1984-01-11 | 1985-08-02 | Chisso Corp | 2-substituted-6-(5-substituted-2-pyrimidinyl)naphthalene |
JPH11171886A (en) * | 1997-12-08 | 1999-06-29 | Mitsui Chem Inc | Pyprolylbenzimidazole derivative having amidine or guanidine in side chain |
CN1309385C (en) * | 2001-12-20 | 2007-04-11 | 惠氏公司 | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
CA2438032C (en) | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Benzothiazole derivative compounds, compositions and uses |
PL1611115T3 (en) * | 2003-03-14 | 2013-01-31 | Univ Pittsburgh Commonwealth Sys Higher Education | Benzothiazole derivative compounds, compositions and uses |
WO2005040337A2 (en) | 2003-05-20 | 2005-05-06 | The Regents Of The University Of California | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES |
AU2003304416A1 (en) * | 2003-08-13 | 2005-03-07 | Bf Research Institute, Inc. | Probe for disease with amyloid deposit, amyloid-staining agent, remedy and preventive for disease with amyloid deposit and diagnostic probe and staining agent for neurofibril change |
AU2007288124B2 (en) | 2006-08-24 | 2013-04-04 | Australian Nuclear Science & Technology Organisation | Fluorinated ligands for targeting peripheral benzodiazepine receptors |
WO2008134618A2 (en) | 2007-04-27 | 2008-11-06 | The General Hospital Corporation | Novel imaging tracers for early detection and treatment of amyloid plaques caused by alzheimer's disease and related disorders |
KR101469275B1 (en) | 2007-06-01 | 2014-12-08 | 재단법인서울대학교산학협력재단 | Heterocyclic indene derivatives and their radioisotope labeled compounds for imaging β-amyloid deposition |
US20090123373A1 (en) | 2007-11-05 | 2009-05-14 | Yanming Wang | Amyloid-imaging agents |
US8153813B2 (en) | 2007-12-20 | 2012-04-10 | Abbott Laboratories | Benzothiazole and benzooxazole derivatives and methods of use |
WO2009146388A1 (en) * | 2008-05-28 | 2009-12-03 | The Trustees Of Columbia University In The City Of New York | Voxel-based methods for assessing subjects using positron emission tomography |
WO2009155017A2 (en) * | 2008-05-30 | 2009-12-23 | Merck & Co., Inc. | Novel substituted azabenzoxazoles |
AU2009309027A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel substituted azabenzoxazoles |
US8691187B2 (en) | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
ES2548571T3 (en) * | 2009-04-02 | 2015-10-19 | Fundación Centro Nacional De Investigaciones Oncológicas Carlos Iii | Imidazo derivatives [2,1-b] [1,3,4] thiadiazole |
GB0905664D0 (en) | 2009-04-02 | 2009-05-13 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
ES2620177T3 (en) * | 2009-10-15 | 2017-06-27 | Guerbet | Imaging agents and their use for in vivo diagnosis of neurodegenerative diseases, particularly Alzheimer's disease and derived diseases |
JP2011168515A (en) | 2010-02-17 | 2011-09-01 | Kowa Co | 2-arylbenzoxazole compound having erythropoietin production-promoting action |
PL3197277T3 (en) | 2014-08-29 | 2022-04-04 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
PL3186233T3 (en) | 2014-08-29 | 2022-02-28 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
CA2959531C (en) | 2014-08-29 | 2023-01-10 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
MX2018002338A (en) | 2015-08-28 | 2018-07-06 | Chdi Foundation Inc | Probes for imaging huntingtin protein. |
-
2015
- 2015-08-28 MX MX2017002705A patent/MX2017002705A/en unknown
- 2015-08-28 AU AU2015308709A patent/AU2015308709B2/en active Active
- 2015-08-28 KR KR1020177008352A patent/KR20170047341A/en not_active Application Discontinuation
- 2015-08-28 BR BR112017004134A patent/BR112017004134A2/en not_active Application Discontinuation
- 2015-08-28 CN CN201580058281.9A patent/CN107105655A/en active Pending
- 2015-08-28 EP EP15836157.6A patent/EP3190888B1/en active Active
- 2015-08-28 JP JP2017530972A patent/JP2017528520A/en not_active Ceased
- 2015-08-28 EA EA201790408A patent/EA201790408A1/en unknown
- 2015-08-28 ES ES15836157T patent/ES2818107T3/en active Active
- 2015-08-28 WO PCT/US2015/047427 patent/WO2016033460A1/en active Application Filing
- 2015-08-28 SG SG11201701580XA patent/SG11201701580XA/en unknown
- 2015-08-28 US US15/507,217 patent/US10907197B2/en active Active
- 2015-08-28 CA CA2959505A patent/CA2959505A1/en not_active Abandoned
-
2017
- 2017-02-27 IL IL250804A patent/IL250804A0/en unknown
-
2020
- 2020-03-30 AU AU2020202226A patent/AU2020202226A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3190888A1 (en) | 2017-07-19 |
AU2020202226A1 (en) | 2020-04-16 |
CA2959505A1 (en) | 2016-03-03 |
KR20170047341A (en) | 2017-05-04 |
US10907197B2 (en) | 2021-02-02 |
AU2015308709A1 (en) | 2017-03-23 |
IL250804A0 (en) | 2017-04-30 |
MX2017002705A (en) | 2017-12-20 |
CN107105655A (en) | 2017-08-29 |
BR112017004134A2 (en) | 2017-12-12 |
JP2017528520A (en) | 2017-09-28 |
EP3190888A4 (en) | 2018-05-09 |
EP3190888B1 (en) | 2020-06-10 |
ES2818107T3 (en) | 2021-04-09 |
US20170292150A1 (en) | 2017-10-12 |
AU2015308709B2 (en) | 2020-01-02 |
WO2016033460A1 (en) | 2016-03-03 |
EA201790408A1 (en) | 2017-09-29 |
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