PL3340796T4 - Sondy do obrazowania białka huntingtyny - Google Patents
Sondy do obrazowania białka huntingtynyInfo
- Publication number
- PL3340796T4 PL3340796T4 PL16842715T PL16842715T PL3340796T4 PL 3340796 T4 PL3340796 T4 PL 3340796T4 PL 16842715 T PL16842715 T PL 16842715T PL 16842715 T PL16842715 T PL 16842715T PL 3340796 T4 PL3340796 T4 PL 3340796T4
- Authority
- PL
- Poland
- Prior art keywords
- probes
- huntingtin protein
- imaging
- imaging huntingtin
- protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nuclear Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562211118P | 2015-08-28 | 2015-08-28 | |
| PCT/US2016/049112 WO2017040336A1 (en) | 2015-08-28 | 2016-08-26 | Probes for imaging huntingtin protein |
| EP16842715.1A EP3340796B1 (en) | 2015-08-28 | 2016-08-26 | Probes for imaging huntingtin protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL3340796T4 true PL3340796T4 (pl) | 2022-02-21 |
| PL3340796T3 PL3340796T3 (pl) | 2022-02-21 |
Family
ID=58103449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16842715T PL3340796T3 (pl) | 2015-08-28 | 2016-08-26 | Sondy do obrazowania białka huntingtyny |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10137211B2 (pl) |
| EP (1) | EP3340796B1 (pl) |
| JP (1) | JP6944929B2 (pl) |
| CN (1) | CN108135172B (pl) |
| AU (1) | AU2016315648B2 (pl) |
| BR (1) | BR112018003331B1 (pl) |
| CA (1) | CA2995847C (pl) |
| DK (1) | DK3340796T3 (pl) |
| ES (1) | ES2885053T3 (pl) |
| HR (1) | HRP20211156T1 (pl) |
| HU (1) | HUE056509T2 (pl) |
| IL (1) | IL257537B (pl) |
| MX (1) | MX2018002338A (pl) |
| PL (1) | PL3340796T3 (pl) |
| PT (1) | PT3340796T (pl) |
| RU (1) | RU2721419C2 (pl) |
| SI (1) | SI3340796T1 (pl) |
| WO (1) | WO2017040336A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3190888B1 (en) | 2014-08-29 | 2020-06-10 | CHDI Foundation, Inc. | Probes for imaging huntingtin protein |
| JP6754353B2 (ja) | 2014-08-29 | 2020-09-09 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | ハンチントンタンパク質のイメージング用プローブ |
| BR112017004136B1 (pt) | 2014-08-29 | 2022-05-03 | Chdi Foundation, Inc | Agente de imagemamento, seu uso e compostos |
| SI3186233T1 (sl) | 2014-08-29 | 2022-04-29 | Chdi Foundation, Inc. | Sonde za slikanje proteina huntingtina |
| HRP20211156T1 (hr) | 2015-08-28 | 2021-12-24 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
| US20210069403A1 (en) * | 2018-02-08 | 2021-03-11 | Phraxis Inc. | One piece anastomotic connector |
| JP2022521431A (ja) | 2019-02-25 | 2022-04-07 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | 変異型ハンチンチンタンパク質を標的とするための化合物及びその使用 |
| MX2022015829A (es) * | 2020-06-11 | 2023-04-05 | Chdi Foundation Inc | Compuestos heterocíclicos y agentes formadores de imágenes para formar la imagen de la proteína huntingtina. |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2126636T3 (es) | 1992-05-19 | 1999-04-01 | Adir | Derivados del bencimidazol con actividad antidiabetica y antiagregante plaquetaria. |
| JP2000351782A (ja) * | 1999-04-06 | 2000-12-19 | Yamanouchi Pharmaceut Co Ltd | メタボトロピックグルタメート受容体作用薬及び新規チアゾロベンゾイミダゾール誘導体 |
| AU2241400A (en) * | 1999-04-06 | 2000-10-12 | Yamanouchi Pharmaceutical Co., Ltd. | Novel thiazolobenzoimidazole derivative |
| UY27003A1 (es) | 2000-11-06 | 2002-07-31 | Schering Ag | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer |
| CA2545711A1 (en) * | 2003-11-13 | 2005-06-02 | Ambit Biosciences Corporation | Urea derivatives as kinase modulators |
| TW201018678A (en) * | 2006-01-27 | 2010-05-16 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| FR2919610B1 (fr) * | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
| JP2011529086A (ja) * | 2008-07-24 | 2011-12-01 | シーメンス メディカル ソリューションズ ユーエスエー インコーポレイテッド | Ａｄ病変を同定するために有用な造影剤 |
| EP2218464A1 (en) * | 2009-02-11 | 2010-08-18 | Technische Universität München | Compounds for non-invasive measurement of aggregates of amyloid peptides |
| EP2411057B1 (en) | 2009-03-23 | 2020-05-06 | Eli Lilly and Company | Imaging agents for detecting neurological disorders |
| IN2015DN00127A (pl) * | 2012-07-11 | 2015-05-29 | Nimbus Iris Inc | |
| US9902702B2 (en) * | 2014-07-15 | 2018-02-27 | Bristol-Myers Squibb Company | Spirocycloheptanes as inhibitors of rock |
| EP3190888B1 (en) | 2014-08-29 | 2020-06-10 | CHDI Foundation, Inc. | Probes for imaging huntingtin protein |
| JP6754353B2 (ja) | 2014-08-29 | 2020-09-09 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | ハンチントンタンパク質のイメージング用プローブ |
| BR112017004136B1 (pt) | 2014-08-29 | 2022-05-03 | Chdi Foundation, Inc | Agente de imagemamento, seu uso e compostos |
| SI3186233T1 (sl) | 2014-08-29 | 2022-04-29 | Chdi Foundation, Inc. | Sonde za slikanje proteina huntingtina |
| HRP20211156T1 (hr) | 2015-08-28 | 2021-12-24 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
-
2016
- 2016-08-26 HR HRP20211156TT patent/HRP20211156T1/hr unknown
- 2016-08-26 MX MX2018002338A patent/MX2018002338A/es unknown
- 2016-08-26 EP EP16842715.1A patent/EP3340796B1/en active Active
- 2016-08-26 ES ES16842715T patent/ES2885053T3/es active Active
- 2016-08-26 PT PT168427151T patent/PT3340796T/pt unknown
- 2016-08-26 HU HUE16842715A patent/HUE056509T2/hu unknown
- 2016-08-26 RU RU2018110055A patent/RU2721419C2/ru active
- 2016-08-26 DK DK16842715.1T patent/DK3340796T3/da active
- 2016-08-26 PL PL16842715T patent/PL3340796T3/pl unknown
- 2016-08-26 BR BR112018003331-6A patent/BR112018003331B1/pt active IP Right Grant
- 2016-08-26 WO PCT/US2016/049112 patent/WO2017040336A1/en active Application Filing
- 2016-08-26 CN CN201680059497.1A patent/CN108135172B/zh active Active
- 2016-08-26 CA CA2995847A patent/CA2995847C/en active Active
- 2016-08-26 US US15/249,223 patent/US10137211B2/en active Active
- 2016-08-26 SI SI201631285T patent/SI3340796T1/sl unknown
- 2016-08-26 AU AU2016315648A patent/AU2016315648B2/en active Active
- 2016-08-26 JP JP2018510377A patent/JP6944929B2/ja active Active
-
2018
- 2018-02-14 IL IL257537A patent/IL257537B/en active IP Right Grant
- 2018-10-26 US US16/172,425 patent/US10765764B2/en active Active
-
2020
- 2020-08-06 US US16/987,277 patent/US11344637B2/en active Active
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