MX380681B - Sistema de control del proceso de regulacion y control de una planta de estructura modular para la obtencion de productos biofarmaceuticos y biologicos macromoleculares. - Google Patents

Sistema de control del proceso de regulacion y control de una planta de estructura modular para la obtencion de productos biofarmaceuticos y biologicos macromoleculares.

Info

Publication number
MX380681B
MX380681B MX2017014527A MX2017014527A MX380681B MX 380681 B MX380681 B MX 380681B MX 2017014527 A MX2017014527 A MX 2017014527A MX 2017014527 A MX2017014527 A MX 2017014527A MX 380681 B MX380681 B MX 380681B
Authority
MX
Mexico
Prior art keywords
biopharmaceutical
regulation
obtaining
modular structure
biological products
Prior art date
Application number
MX2017014527A
Other languages
English (en)
Spanish (es)
Other versions
MX2017014527A (es
Inventor
Jens Bernshausen
Martin Lobedann
Peter Schwan
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53177195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX380681(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX2017014527A publication Critical patent/MX2017014527A/es
Publication of MX380681B publication Critical patent/MX380681B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/06—Control of flow characterised by the use of electric means
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B11/00—Automatic controllers
    • G05B11/01—Automatic controllers electric
    • G05B11/36—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
    • G05B11/42—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P. I., P. I. D.
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/0265—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion
    • G05B13/0275—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion using fuzzy logic only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Medical Informatics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feedback Control In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Testing And Monitoring For Control Systems (AREA)
  • Flow Control (AREA)
  • Peptides Or Proteins (AREA)
MX2017014527A 2015-05-13 2016-05-10 Sistema de control del proceso de regulacion y control de una planta de estructura modular para la obtencion de productos biofarmaceuticos y biologicos macromoleculares. MX380681B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15167538.6A EP3093335A1 (de) 2015-05-13 2015-05-13 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten
PCT/EP2016/060369 WO2016180798A1 (de) 2015-05-13 2016-05-10 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten

Publications (2)

Publication Number Publication Date
MX2017014527A MX2017014527A (es) 2018-03-12
MX380681B true MX380681B (es) 2025-03-12

Family

ID=53177195

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017014527A MX380681B (es) 2015-05-13 2016-05-10 Sistema de control del proceso de regulacion y control de una planta de estructura modular para la obtencion de productos biofarmaceuticos y biologicos macromoleculares.

Country Status (21)

Country Link
US (2) US20180127461A1 (cg-RX-API-DMAC10.html)
EP (2) EP3093335A1 (cg-RX-API-DMAC10.html)
JP (1) JP6833721B2 (cg-RX-API-DMAC10.html)
KR (1) KR20180005225A (cg-RX-API-DMAC10.html)
CN (1) CN107849506B (cg-RX-API-DMAC10.html)
AR (1) AR104554A1 (cg-RX-API-DMAC10.html)
AU (1) AU2016259746B2 (cg-RX-API-DMAC10.html)
BR (1) BR112017024373B1 (cg-RX-API-DMAC10.html)
CA (1) CA2985678A1 (cg-RX-API-DMAC10.html)
DK (1) DK3294856T3 (cg-RX-API-DMAC10.html)
ES (1) ES2760468T3 (cg-RX-API-DMAC10.html)
IL (1) IL255556B (cg-RX-API-DMAC10.html)
MX (1) MX380681B (cg-RX-API-DMAC10.html)
PL (1) PL3294856T3 (cg-RX-API-DMAC10.html)
PT (1) PT3294856T (cg-RX-API-DMAC10.html)
RU (1) RU2724495C2 (cg-RX-API-DMAC10.html)
SA (1) SA517390330B1 (cg-RX-API-DMAC10.html)
SG (1) SG11201709329YA (cg-RX-API-DMAC10.html)
TW (1) TWI689303B (cg-RX-API-DMAC10.html)
WO (1) WO2016180798A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201708418B (cg-RX-API-DMAC10.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3431173A1 (en) 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
AU2019335063A1 (en) * 2018-09-05 2021-01-07 Commonwealth Scientific And Industrial Research Organisation "a monitor for a multi-parameter manufacturing process"
EP3699697A1 (en) 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
JP7604486B2 (ja) * 2020-05-29 2024-12-23 株式会社ダイセル 異常変調原因特定装置、異常変調原因特定方法及び異常変調原因特定プログラム
DE102022208467A1 (de) 2022-06-24 2024-01-04 Bilfinger Life Science Gmbh Modulare Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biotechnologischen Produkten
WO2023247798A1 (de) 2022-06-24 2023-12-28 Bilfinger Life Science Gmbh Modulare vorrichtung und verfahren zur kontinuierlichen herstellung von biotechnologischen produkten
EP4711439A1 (en) 2024-09-16 2026-03-18 Sartorius Stedim Biotech GmbH Flow system with recirculation loop

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5546594A (en) * 1992-11-06 1994-06-08 Abbott Laboratories Process control system for biological fluid testing
JP2004198123A (ja) * 2002-12-16 2004-07-15 Shimadzu Corp 分取液体クロマトグラフ質量分析装置
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP2006018711A (ja) * 2004-07-05 2006-01-19 Earekkusu:Kk 液体除染剤供給システム
CN102794109B (zh) 2004-09-30 2015-10-07 拜耳医药保健有限公司 用于集成连续生产生物分子的装置和方法
JP2008539738A (ja) * 2005-05-09 2008-11-20 サクソニア バイオテック ゲーエムベーハー 細胞培養モジュール用供給システム
US9103814B2 (en) * 2006-03-17 2015-08-11 Waters Technologies Corporation Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients
JP4831480B2 (ja) * 2006-06-21 2011-12-07 三浦工業株式会社 膜濾過システム
US9891157B2 (en) * 2010-12-03 2018-02-13 Cellply S.R.L. Microanalysis of cellular function
CN103562145B (zh) * 2010-12-06 2016-09-21 颇尔公司 生物制品的连续加工方法
CN103243026B (zh) * 2012-02-14 2014-09-03 常州医凌生命科技有限公司 多功能全自动细胞及溶液处理仪
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
US10203308B2 (en) * 2013-01-18 2019-02-12 Shimadzu Corporation Sample concentration device
AU2014226126B2 (en) 2013-03-08 2019-02-14 Genzyme Corporation Continuous purification of therapeutic proteins
DE102013212540A1 (de) * 2013-06-27 2014-12-31 Agilent Technologies Inc. Konditionieren eines nachfolgenden Probenpakets in einer Probentrennstufe während Prozessierens eines vorangehenden Probenpakets in einer Probenweiterverarbeitungsstufe
EP3186355A4 (en) * 2014-07-31 2018-03-21 Govind Rao Microscale bioprocessing system and method for protein manufacturing from human blood

Also Published As

Publication number Publication date
IL255556A (en) 2018-01-31
AR104554A1 (es) 2017-07-26
HK1252939A1 (zh) 2019-06-06
AU2016259746A8 (en) 2018-04-05
DK3294856T3 (da) 2019-12-09
PL3294856T3 (pl) 2020-04-30
ES2760468T3 (es) 2020-05-14
BR112017024373B1 (pt) 2022-08-09
CA2985678A1 (en) 2016-11-17
EP3294856B1 (de) 2019-09-18
RU2017143437A3 (cg-RX-API-DMAC10.html) 2019-08-29
MX2017014527A (es) 2018-03-12
EP3294856A1 (de) 2018-03-21
US20180127461A1 (en) 2018-05-10
TW201717886A (zh) 2017-06-01
CN107849506A (zh) 2018-03-27
TWI689303B (zh) 2020-04-01
US20210221842A1 (en) 2021-07-22
AU2016259746B2 (en) 2020-12-24
CN107849506B (zh) 2020-11-03
RU2017143437A (ru) 2019-06-13
JP6833721B2 (ja) 2021-02-24
RU2724495C2 (ru) 2020-06-23
AU2016259746A1 (en) 2017-12-07
ZA201708418B (en) 2022-08-31
KR20180005225A (ko) 2018-01-15
SG11201709329YA (en) 2017-12-28
IL255556B (en) 2022-04-01
BR112017024373A2 (pt) 2018-07-31
JP2018524668A (ja) 2018-08-30
SA517390330B1 (ar) 2021-09-22
EP3093335A1 (de) 2016-11-16
WO2016180798A1 (de) 2016-11-17
PT3294856T (pt) 2019-12-16

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