SG11201709329YA - Process control system for regulating and controlling a modular plant for manufacturing biopharmaceutical and biological macromolecular products - Google Patents

Process control system for regulating and controlling a modular plant for manufacturing biopharmaceutical and biological macromolecular products

Info

Publication number
SG11201709329YA
SG11201709329YA SG11201709329YA SG11201709329YA SG11201709329YA SG 11201709329Y A SG11201709329Y A SG 11201709329YA SG 11201709329Y A SG11201709329Y A SG 11201709329YA SG 11201709329Y A SG11201709329Y A SG 11201709329YA SG 11201709329Y A SG11201709329Y A SG 11201709329YA
Authority
SG
Singapore
Prior art keywords
biopharmaceutical
regulating
manufacturing
controlling
control system
Prior art date
Application number
SG11201709329YA
Inventor
Peter Schwan
Martin Lobedann
Jens Bernshausen
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53177195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201709329Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG11201709329YA publication Critical patent/SG11201709329YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/44Multiple separable units; Modules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00Control of flow
    • G05D7/06Control of flow characterised by the use of electric means
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B11/00Automatic controllers
    • G05B11/01Automatic controllers electric
    • G05B11/36Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
    • G05B11/42Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P. I., P. I. D.
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/0265Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion
    • G05B13/0275Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion using fuzzy logic only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Medical Informatics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Feedback Control In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Testing And Monitoring For Control Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Flow Control (AREA)
SG11201709329YA 2015-05-13 2016-05-10 Process control system for regulating and controlling a modular plant for manufacturing biopharmaceutical and biological macromolecular products SG11201709329YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15167538.6A EP3093335A1 (en) 2015-05-13 2015-05-13 Process control system for regulating and controlling a modular system for the production of biopharmaceutical and biological macromolecular products
PCT/EP2016/060369 WO2016180798A1 (en) 2015-05-13 2016-05-10 Process control system for regulating and controlling a modular plant for manufacturing biopharmaceutical and biological macromolecular products

Publications (1)

Publication Number Publication Date
SG11201709329YA true SG11201709329YA (en) 2017-12-28

Family

ID=53177195

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201709329YA SG11201709329YA (en) 2015-05-13 2016-05-10 Process control system for regulating and controlling a modular plant for manufacturing biopharmaceutical and biological macromolecular products

Country Status (22)

Country Link
US (2) US20180127461A1 (en)
EP (2) EP3093335A1 (en)
JP (1) JP6833721B2 (en)
KR (1) KR20180005225A (en)
CN (1) CN107849506B (en)
AR (1) AR104554A1 (en)
AU (1) AU2016259746B2 (en)
BR (1) BR112017024373B1 (en)
CA (1) CA2985678A1 (en)
DK (1) DK3294856T3 (en)
ES (1) ES2760468T3 (en)
HK (1) HK1252939A1 (en)
IL (1) IL255556B (en)
MX (1) MX2017014527A (en)
PL (1) PL3294856T3 (en)
PT (1) PT3294856T (en)
RU (1) RU2724495C2 (en)
SA (1) SA517390330B1 (en)
SG (1) SG11201709329YA (en)
TW (1) TWI689303B (en)
WO (1) WO2016180798A1 (en)
ZA (1) ZA201708418B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3431173A1 (en) 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
WO2020047578A1 (en) * 2018-09-05 2020-03-12 Commonwealth Scientific And Industrial Research Organisation "a monitor for a multi-parameter manufacturing process"
WO2021241580A1 (en) * 2020-05-29 2021-12-02 株式会社ダイセル Abnormality/irregularity cause identifying apparatus, abnormality/irregularity cause identifying method, and abnormality/irregularity cause identifying program
DE102022208467A1 (en) 2022-06-24 2024-01-04 Bilfinger Life Science Gmbh Modular device and method for the continuous production of biotechnological products
WO2023247798A1 (en) 2022-06-24 2023-12-28 Bilfinger Life Science Gmbh Modular device and method for continuously producing biotechnological products

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5546594A (en) * 1992-11-06 1994-06-08 Abbott Laboratories Process control system for biological fluid testing
JP2004198123A (en) * 2002-12-16 2004-07-15 Shimadzu Corp Preparative liquid chromatograph mass spectroscope
JP3823092B2 (en) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ Separation analyzer
JP2006018711A (en) * 2004-07-05 2006-01-19 Earekkusu:Kk Liquid decontamination agent supply system
PT2550971T (en) 2004-09-30 2017-10-02 Bayer Healthcare Llc Devices and methods for integrated continuous manufacturing of biological molecules
EP1882030B1 (en) * 2005-05-09 2014-08-06 ALPHA PLAN GmbH Apparatus for providing media to cell culture modules
WO2007109157A2 (en) * 2006-03-17 2007-09-27 Waters Investments Limited Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients
JP4831480B2 (en) * 2006-06-21 2011-12-07 三浦工業株式会社 Membrane filtration system
CN105842435B (en) * 2010-12-03 2019-03-05 塞普莱有限公司 The microanalysis of cell function
EP2649016B1 (en) 2010-12-06 2020-06-10 Pall Corporation Continuous processing methods for biological products
CN103243026B (en) * 2012-02-14 2014-09-03 常州医凌生命科技有限公司 Multifunctional full-automatic cell and solution treating instrument
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
WO2014112527A1 (en) * 2013-01-18 2014-07-24 株式会社島津製作所 Sample concentration device
SG10201709131UA (en) 2013-03-08 2017-12-28 Genzyme Corp Continuous purification of therapeutic proteins
DE102013212540A1 (en) * 2013-06-27 2014-12-31 Agilent Technologies Inc. Conditioning a subsequent sample packet in a sample separation stage while processing a previous sample package in a sample processing stage
BR112017002083B1 (en) * 2014-07-31 2022-04-05 Govind Rao Bioprocessing system for the manufacture of blood protein

Also Published As

Publication number Publication date
CA2985678A1 (en) 2016-11-17
RU2724495C2 (en) 2020-06-23
PL3294856T3 (en) 2020-04-30
TWI689303B (en) 2020-04-01
AU2016259746A1 (en) 2017-12-07
DK3294856T3 (en) 2019-12-09
AU2016259746A8 (en) 2018-04-05
CN107849506B (en) 2020-11-03
EP3294856B1 (en) 2019-09-18
ES2760468T3 (en) 2020-05-14
JP6833721B2 (en) 2021-02-24
EP3294856A1 (en) 2018-03-21
BR112017024373A2 (en) 2018-07-31
JP2018524668A (en) 2018-08-30
AR104554A1 (en) 2017-07-26
ZA201708418B (en) 2022-08-31
KR20180005225A (en) 2018-01-15
AU2016259746B2 (en) 2020-12-24
TW201717886A (en) 2017-06-01
CN107849506A (en) 2018-03-27
MX2017014527A (en) 2018-03-12
RU2017143437A3 (en) 2019-08-29
SA517390330B1 (en) 2021-09-22
EP3093335A1 (en) 2016-11-16
US20180127461A1 (en) 2018-05-10
US20210221842A1 (en) 2021-07-22
BR112017024373B1 (en) 2022-08-09
WO2016180798A1 (en) 2016-11-17
IL255556A (en) 2018-01-31
HK1252939A1 (en) 2019-06-06
RU2017143437A (en) 2019-06-13
IL255556B (en) 2022-04-01
PT3294856T (en) 2019-12-16

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