AR104554A1 - Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares - Google Patents

Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares

Info

Publication number
AR104554A1
AR104554A1 ARP160101310A ARP160101310A AR104554A1 AR 104554 A1 AR104554 A1 AR 104554A1 AR P160101310 A ARP160101310 A AR P160101310A AR P160101310 A ARP160101310 A AR P160101310A AR 104554 A1 AR104554 A1 AR 104554A1
Authority
AR
Argentina
Prior art keywords
biopharmaceutical
modular structure
biological products
regulation
control system
Prior art date
Application number
ARP160101310A
Other languages
English (en)
Inventor
Dr Bernshausen Jens
Dr Lobedann Martin
Dr Schwan Peter
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53177195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR104554(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR104554A1 publication Critical patent/AR104554A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/06—Control of flow characterised by the use of electric means
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B11/00—Automatic controllers
    • G05B11/01—Automatic controllers electric
    • G05B11/36—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
    • G05B11/42—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P. I., P. I. D.
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/0265—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion
    • G05B13/0275—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion using fuzzy logic only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Medical Informatics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feedback Control In General (AREA)
  • Testing And Monitoring For Control Systems (AREA)
  • Flow Control (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente se refiere a una planta de producción de estructura modular para la obtención y/o tratamiento continuo de productos biofarmacéuticos, a un procedimiento implementado por computadora para controlar el proceso de la planta de estructura modular para la producción de productos biofarmacéuticos y biológicos macromoleculares, en particular de proteínas, por ejemplo anticuerpos monoclonales, vacunas, ácidos nucleicos como ADN, ARN y plásmidos y derivados de plásmidos.
ARP160101310A 2015-05-13 2016-05-06 Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares AR104554A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15167538.6A EP3093335A1 (de) 2015-05-13 2015-05-13 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten

Publications (1)

Publication Number Publication Date
AR104554A1 true AR104554A1 (es) 2017-07-26

Family

ID=53177195

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160101310A AR104554A1 (es) 2015-05-13 2016-05-06 Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares

Country Status (22)

Country Link
US (2) US20180127461A1 (es)
EP (2) EP3093335A1 (es)
JP (1) JP6833721B2 (es)
KR (1) KR20180005225A (es)
CN (1) CN107849506B (es)
AR (1) AR104554A1 (es)
AU (1) AU2016259746B2 (es)
BR (1) BR112017024373B1 (es)
CA (1) CA2985678A1 (es)
DK (1) DK3294856T3 (es)
ES (1) ES2760468T3 (es)
HK (1) HK1252939A1 (es)
IL (1) IL255556B (es)
MX (1) MX2017014527A (es)
PL (1) PL3294856T3 (es)
PT (1) PT3294856T (es)
RU (1) RU2724495C2 (es)
SA (1) SA517390330B1 (es)
SG (1) SG11201709329YA (es)
TW (1) TWI689303B (es)
WO (1) WO2016180798A1 (es)
ZA (1) ZA201708418B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3431173A1 (en) 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
WO2020047578A1 (en) * 2018-09-05 2020-03-12 Commonwealth Scientific And Industrial Research Organisation "a monitor for a multi-parameter manufacturing process"
JPWO2021241580A1 (es) * 2020-05-29 2021-12-02
WO2023247798A1 (de) 2022-06-24 2023-12-28 Bilfinger Life Science Gmbh Modulare vorrichtung und verfahren zur kontinuierlichen herstellung von biotechnologischen produkten
DE102022208467A1 (de) 2022-06-24 2024-01-04 Bilfinger Life Science Gmbh Modulare Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biotechnologischen Produkten

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011838A1 (en) * 1992-11-06 1994-05-26 Abbott Laboratories Process control system for biological fluid testing
JP2004198123A (ja) * 2002-12-16 2004-07-15 Shimadzu Corp 分取液体クロマトグラフ質量分析装置
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP2006018711A (ja) * 2004-07-05 2006-01-19 Earekkusu:Kk 液体除染剤供給システム
KR101335936B1 (ko) 2004-09-30 2013-12-03 바이엘 헬스케어, 엘엘씨 생물학적 분자의 통합된 연속 제조를 위한 장치 및 방법
AU2006246263A1 (en) * 2005-05-09 2006-11-16 Saxonia Biotec Gmbh. Apparatus for providing media to cell culture modules
EP1996303B1 (en) * 2006-03-17 2018-05-02 Waters Technologies Corporation Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients
JP4831480B2 (ja) * 2006-06-21 2011-12-07 三浦工業株式会社 膜濾過システム
US9891157B2 (en) * 2010-12-03 2018-02-13 Cellply S.R.L. Microanalysis of cellular function
EP2649016B1 (en) 2010-12-06 2020-06-10 Pall Corporation Continuous processing methods for biological products
CN103243026B (zh) * 2012-02-14 2014-09-03 常州医凌生命科技有限公司 多功能全自动细胞及溶液处理仪
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
CN104903722B (zh) * 2013-01-18 2017-07-14 株式会社岛津制作所 样品浓缩装置
AU2014226126B2 (en) 2013-03-08 2019-02-14 Genzyme Corporation Continuous purification of therapeutic proteins
DE102013212540A1 (de) * 2013-06-27 2014-12-31 Agilent Technologies Inc. Konditionieren eines nachfolgenden Probenpakets in einer Probentrennstufe während Prozessierens eines vorangehenden Probenpakets in einer Probenweiterverarbeitungsstufe
US20170226467A1 (en) * 2014-07-31 2017-08-10 Govind Rao Microscale bioprocessing system and method for protein manufacturing from human blood

Also Published As

Publication number Publication date
AU2016259746B2 (en) 2020-12-24
WO2016180798A1 (de) 2016-11-17
AU2016259746A1 (en) 2017-12-07
SA517390330B1 (ar) 2021-09-22
BR112017024373B1 (pt) 2022-08-09
BR112017024373A2 (pt) 2018-07-31
EP3294856A1 (de) 2018-03-21
RU2017143437A (ru) 2019-06-13
TW201717886A (zh) 2017-06-01
IL255556A (en) 2018-01-31
US20210221842A1 (en) 2021-07-22
ES2760468T3 (es) 2020-05-14
SG11201709329YA (en) 2017-12-28
PL3294856T3 (pl) 2020-04-30
PT3294856T (pt) 2019-12-16
JP2018524668A (ja) 2018-08-30
JP6833721B2 (ja) 2021-02-24
US20180127461A1 (en) 2018-05-10
EP3294856B1 (de) 2019-09-18
EP3093335A1 (de) 2016-11-16
HK1252939A1 (zh) 2019-06-06
MX2017014527A (es) 2018-03-12
IL255556B (en) 2022-04-01
DK3294856T3 (da) 2019-12-09
AU2016259746A8 (en) 2018-04-05
CA2985678A1 (en) 2016-11-17
CN107849506A (zh) 2018-03-27
RU2724495C2 (ru) 2020-06-23
CN107849506B (zh) 2020-11-03
ZA201708418B (en) 2022-08-31
RU2017143437A3 (es) 2019-08-29
KR20180005225A (ko) 2018-01-15
TWI689303B (zh) 2020-04-01

Similar Documents

Publication Publication Date Title
AR104554A1 (es) Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares
EA201700497A1 (ru) Способ культивирования бактерий
BR112017008518A2 (pt) indutores de haploidia
EP3293265A4 (en) Production method for exosome comprising target protein, and method for transferring target protein into cytoplasm by using exosome produced by means of the production method
EP4249036A3 (en) Methods and products for nucleic acid production and delivery
MX2018004265A (es) Metodo para producir plantas de genoma modificado a partir de protoplastos de planta a alta eficiencia.
AR099462A1 (es) Unidad de ultrafiltración para el intercambio continuo de medio o tampón de una solución proteica
BR112016015187A2 (pt) proteína de fusão para inibição da angiogênese ou do crescimento e uso da mesma
AR095662A1 (es) Elementos reguladores de plantas y sus usos
SG11201802922QA (en) Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same
CR20150554A (es) Elementos regulatorios de planta y sus usos
CO2017009163A2 (es) Moléculas de ácido nucleico de arn polimerasa ii33 para el control de plagas de insectos
MX351264B (es) Proteína quitinasa insecticida novedosa, su nucleótido codificador y su aplicación.
PH12019502000A1 (en) Pharmaceutical combinations comprising an anti-ly75 antibody
BR112017012389A2 (pt) supressão de rnai parental de gene kruppel para controlar pragas de coleóptero
CO2017009158A2 (es) Moléculas de ácido nucleico de arn polimerasa ii215 para el control de plagas de insectos
AR103038A1 (es) SUPRESIÓN DE iARN PARENTAL DE LOS GENES DE REMODELACIÓN DE CROMATINA PARA CONTROLAR LAS PLAGAS DE HEMÍPTEROS
MY176569A (en) Method of removing dna from biotechnological products
AR106857A1 (es) Elementos reguladores de plantas y métodos para usarlos
CO2017003557A2 (es) Moleculas de acido nucleico gho/sec24b2 y sec24b1 para controlar plagas de coleopteros y hemipteros
CO2017006535A2 (es) Supresión por iarn parental del gen kruppel para el control de las plagas de hemípteros
AR110040A1 (es) Proteínas de unión biespecíficas
GB2544841B (en) Method for interrogating mixtures of nucleic acids by short tandem repeat analysis
BR112018006358A2 (pt) métodos de conservação da atividade biológica de ácidos ribonucleicos.
GB201617643D0 (en) Method for complete. uniform and specific amplification of ultra-low amounts of input DNA