MX376790B - Células presentadoras de antígeno artificiales de nanoescala. - Google Patents

Células presentadoras de antígeno artificiales de nanoescala.

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Publication number
MX376790B
MX376790B MX2015012920A MX2015012920A MX376790B MX 376790 B MX376790 B MX 376790B MX 2015012920 A MX2015012920 A MX 2015012920A MX 2015012920 A MX2015012920 A MX 2015012920A MX 376790 B MX376790 B MX 376790B
Authority
MX
Mexico
Prior art keywords
presenting cells
antigen presenting
artificial antigen
nanoscale artificial
nanoscale
Prior art date
Application number
MX2015012920A
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English (en)
Other versions
MX2015012920A (es
Inventor
Jonathan Schneck
Karlo Perica
Mathias Oelke
Original Assignee
Univ Johns Hopkins
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Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of MX2015012920A publication Critical patent/MX2015012920A/es
Publication of MX376790B publication Critical patent/MX376790B/es

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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/24—Antigen-presenting cells [APC]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Peptides Or Proteins (AREA)
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Abstract

La presente invención se refiere a Células Presentadoras de Antígeno Artificial de nano-escala (aAPC), que entregan señales estimuladoras a los linfocitos, incluyendo linfocitos citotóxicos, para su uso como una herramienta poderosa para la inmunoterapia.
MX2015012920A 2013-03-14 2014-03-13 Células presentadoras de antígeno artificiales de nanoescala. MX376790B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786135P 2013-03-14 2013-03-14
US201461942797P 2014-02-21 2014-02-21
PCT/US2014/025889 WO2014160132A1 (en) 2013-03-14 2014-03-13 Nanoscale artificial antigen presenting cells

Publications (2)

Publication Number Publication Date
MX2015012920A MX2015012920A (es) 2016-06-02
MX376790B true MX376790B (es) 2025-03-07

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MX2015012920A MX376790B (es) 2013-03-14 2014-03-13 Células presentadoras de antígeno artificiales de nanoescala.

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US (2) US10435668B2 (es)
EP (1) EP2970907B1 (es)
JP (1) JP6632072B2 (es)
KR (1) KR102164405B1 (es)
CN (1) CN105431523B (es)
AU (1) AU2014244119B2 (es)
CA (1) CA2906514C (es)
ES (1) ES2782002T3 (es)
IL (1) IL241627B (es)
MX (1) MX376790B (es)
SG (2) SG11201507506RA (es)
WO (1) WO2014160132A1 (es)

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