MX371093B - Compuestos de microarn y metodos para modular al mir-122. - Google Patents

Compuestos de microarn y metodos para modular al mir-122.

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Publication number
MX371093B
MX371093B MX2015014816A MX2015014816A MX371093B MX 371093 B MX371093 B MX 371093B MX 2015014816 A MX2015014816 A MX 2015014816A MX 2015014816 A MX2015014816 A MX 2015014816A MX 371093 B MX371093 B MX 371093B
Authority
MX
Mexico
Prior art keywords
methods
mir
compositions
compounds
modulating mir
Prior art date
Application number
MX2015014816A
Other languages
English (en)
Other versions
MX2015014816A (es
Inventor
Bhat Balkrishen
Hogan Daniel
Original Assignee
Regulus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regulus Therapeutics Inc filed Critical Regulus Therapeutics Inc
Publication of MX2015014816A publication Critical patent/MX2015014816A/es
Publication of MX371093B publication Critical patent/MX371093B/es

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Abstract

En la presente se describen composiciones y métodos para la inhibición de la actividad de miR-122. Las composiciones poseen determinadas modificaciones nucleosídicas que proporcionan inhibidores potentes de la actividad de miR-122. Los compuestos pueden comprender conjugados para facilitar la distribución en el hígado. Las composiciones pueden ser administradas a sujetos infectados con el virus de la hepatitis C, como un tratamiento contra el virus de la hepatitis C y enfermedades relacionadas.
MX2015014816A 2013-05-01 2014-04-30 Compuestos de microarn y metodos para modular al mir-122. MX371093B (es)

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US10150967B2 (en) 2018-12-11
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