MX370416B - Formulaciones con oxidacion reducida. - Google Patents

Formulaciones con oxidacion reducida.

Info

Publication number
MX370416B
MX370416B MX2015011433A MX2015011433A MX370416B MX 370416 B MX370416 B MX 370416B MX 2015011433 A MX2015011433 A MX 2015011433A MX 2015011433 A MX2015011433 A MX 2015011433A MX 370416 B MX370416 B MX 370416B
Authority
MX
Mexico
Prior art keywords
formulations
protein
methods
oxidation
reduced oxidation
Prior art date
Application number
MX2015011433A
Other languages
English (en)
Other versions
MX2015011433A (es
Inventor
Sreedhara Alavattam
Mary Mallaney
Parbir Grewal
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2015011433A publication Critical patent/MX2015011433A/es
Publication of MX370416B publication Critical patent/MX370416B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Lubricants (AREA)

Abstract

La presente invención se refiere a formulaciones que comprenden una proteína en combinación con un compuesto que impide la oxidación de la proteína. La invención también proporciona métodos para elaborar estas formulaciones y métodos para usar estas formulaciones. La invención proporciona además métodos para examinar compuestos para impedir la oxidación de una proteína en una composición de proteína y métodos para prevenir la oxidación de una proteína en una formulación.
MX2015011433A 2013-03-13 2014-03-13 Formulaciones con oxidacion reducida. MX370416B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780852P 2013-03-13 2013-03-13
US201361909850P 2013-11-27 2013-11-27
PCT/US2014/026850 WO2014160497A1 (en) 2013-03-13 2014-03-13 Formulations with reduced oxidation

Publications (2)

Publication Number Publication Date
MX2015011433A MX2015011433A (es) 2016-04-27
MX370416B true MX370416B (es) 2019-12-10

Family

ID=51625443

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011433A MX370416B (es) 2013-03-13 2014-03-13 Formulaciones con oxidacion reducida.

Country Status (19)

Country Link
EP (1) EP2968467B1 (es)
JP (2) JP6606059B2 (es)
KR (2) KR102238379B1 (es)
CN (1) CN105209058A (es)
BR (1) BR112015022475A8 (es)
CA (2) CA2904169C (es)
DK (1) DK2968467T3 (es)
ES (1) ES2808823T3 (es)
HK (1) HK1212613A1 (es)
HR (1) HRP20201161T1 (es)
HU (1) HUE049707T2 (es)
LT (1) LT2968467T (es)
MX (1) MX370416B (es)
PL (1) PL2968467T3 (es)
PT (1) PT2968467T (es)
RS (1) RS60534B1 (es)
RU (2) RU2019137020A (es)
SI (1) SI2968467T1 (es)
WO (1) WO2014160497A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
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EP3827846B1 (en) 2015-08-18 2024-10-02 Rakuten Medical, Inc. Compositions, combinations and related methods for photoimmunotherapy
WO2017031363A2 (en) * 2015-08-18 2017-02-23 Aspyrian Therapeutics, Inc. Methods for manufacturing phthalocyanine dye conjugates and stable conjugates
CA3106537A1 (en) * 2018-08-08 2020-02-13 Genentech, Inc. Use of tryptophan derivatives and l-methionine for protein formulation

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Also Published As

Publication number Publication date
HUE049707T2 (hu) 2020-11-30
BR112015022475A8 (pt) 2019-11-26
RU2707550C2 (ru) 2019-11-27
MX2015011433A (es) 2016-04-27
KR102317151B1 (ko) 2021-10-26
DK2968467T3 (da) 2020-08-10
CA2904169C (en) 2021-12-07
HRP20201161T1 (hr) 2020-11-13
PL2968467T3 (pl) 2020-10-19
JP6606059B2 (ja) 2019-11-13
KR20210040190A (ko) 2021-04-12
JP2016513667A (ja) 2016-05-16
ES2808823T3 (es) 2021-03-02
EP2968467B1 (en) 2020-06-03
KR102238379B1 (ko) 2021-04-09
WO2014160497A1 (en) 2014-10-02
CA2904169A1 (en) 2014-10-02
RU2019137020A (ru) 2021-01-14
EP2968467A4 (en) 2016-09-21
EP2968467A1 (en) 2016-01-20
PT2968467T (pt) 2020-07-28
KR20150130396A (ko) 2015-11-23
RS60534B1 (sr) 2020-08-31
HK1212613A1 (zh) 2016-06-17
CA3135558A1 (en) 2014-10-02
RU2015143549A (ru) 2017-04-20
JP2019167349A (ja) 2019-10-03
CN105209058A (zh) 2015-12-30
LT2968467T (lt) 2020-08-25
SI2968467T1 (sl) 2020-11-30
BR112015022475A2 (pt) 2017-07-18

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