MX370134B - Enzimas de cetol-acido reductoisomerasa y metodo de uso. - Google Patents
Enzimas de cetol-acido reductoisomerasa y metodo de uso.Info
- Publication number
- MX370134B MX370134B MX2018004620A MX2018004620A MX370134B MX 370134 B MX370134 B MX 370134B MX 2018004620 A MX2018004620 A MX 2018004620A MX 2018004620 A MX2018004620 A MX 2018004620A MX 370134 B MX370134 B MX 370134B
- Authority
- MX
- Mexico
- Prior art keywords
- ketol
- methods
- acid reductoisomerase
- polypeptides
- reductoisomerase enzymes
- Prior art date
Links
- 108010000200 Ketol-acid reductoisomerase Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 230000006696 biosynthetic metabolic pathway Effects 0.000 abstract 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645832P | 2012-05-11 | 2012-05-11 | |
| US201361787480P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/040627 WO2013176909A2 (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX370134B true MX370134B (es) | 2019-12-03 |
Family
ID=48877508
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018004620A MX370134B (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodo de uso. |
| MX2014013446A MX2014013446A (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodos de uso. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014013446A MX2014013446A (es) | 2012-05-11 | 2013-05-10 | Enzimas de cetol-acido reductoisomerasa y metodos de uso. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9169467B2 (enExample) |
| EP (1) | EP2847326A2 (enExample) |
| JP (1) | JP6321631B2 (enExample) |
| KR (1) | KR20150014953A (enExample) |
| CN (1) | CN104619835B (enExample) |
| AU (1) | AU2013266727A1 (enExample) |
| BR (1) | BR112014028153A2 (enExample) |
| CA (1) | CA2873109A1 (enExample) |
| MX (2) | MX370134B (enExample) |
| NZ (1) | NZ701099A (enExample) |
| WO (1) | WO2013176909A2 (enExample) |
| ZA (1) | ZA201407713B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| MX2011003313A (es) | 2008-09-29 | 2011-06-16 | Butamax Tm Advanced Biofuels | Actividad enzimatica de fe-s heterologa aumentada en levadura. |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| WO2011103300A2 (en) | 2010-02-17 | 2011-08-25 | Butamax(Tm) Advanced Biofuels Llc | Improving activity of fe-s cluster requiring proteins |
| EP2614138B1 (en) | 2010-09-07 | 2017-08-30 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
| US9238828B2 (en) | 2011-07-28 | 2016-01-19 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
| JP2015510774A (ja) | 2012-03-23 | 2015-04-13 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ブタノール産生菌用培地の酢酸補給 |
| AU2013266727A1 (en) | 2012-05-11 | 2014-11-06 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| AU2013305714A1 (en) | 2012-08-22 | 2015-02-05 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| JP6407869B2 (ja) | 2012-09-26 | 2018-10-17 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトール酸レダクトイソメラーゼ活性を有するポリペプチド |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| CA2957920A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
| EP3538545A1 (en) | 2016-11-09 | 2019-09-18 | Danisco US Inc. | Yeast with improved alcohol production |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| KR101960501B1 (ko) * | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Nadh 친화적인 신규 케톨산 리덕토아이소머라제 |
| US11308274B2 (en) | 2019-05-17 | 2022-04-19 | International Business Machines Corporation | Word grouping using a plurality of models |
| CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
| WO2024197704A1 (zh) * | 2023-03-30 | 2024-10-03 | 安徽华恒生物科技股份有限公司 | 一种产泛解酸的重组微生物及其应用 |
| CN117417949B (zh) * | 2023-10-19 | 2024-12-20 | 云南农业大学 | 雪胆细胞色素氧化酶HcCYP81Q58转基因酵母工程菌及其应用 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
| FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
| US6514733B1 (en) | 1999-08-18 | 2003-02-04 | E. I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high titer |
| US20020061569A1 (en) | 2000-03-21 | 2002-05-23 | Robert Haselbeck | Identification of essential genes in prokaryotes |
| US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
| US20040248250A1 (en) | 2001-07-02 | 2004-12-09 | Takahisa Nakai | Method for modifying enzyme and oxidoreductive variant |
| MXPA05009553A (es) | 2003-03-10 | 2006-03-17 | Broin And Associates Inc | Metodo para producir etanol utilizando almidon como materia prima. |
| SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
| WO2006110900A2 (en) | 2005-04-12 | 2006-10-19 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain ethanol |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
| NZ566406A (en) | 2005-10-26 | 2012-04-27 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8273558B2 (en) * | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| PL389665A1 (pl) | 2007-02-09 | 2010-07-05 | The Regents of the University of CaliforniaThe Regents of the University of California | Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| WO2009059254A2 (en) | 2007-10-31 | 2009-05-07 | Gevo, Inc | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
| DE602007011966D1 (de) | 2007-12-17 | 2011-02-24 | Suntory Holdings Ltd | Mutantes ilv5-gen und verwendung davon |
| EP2677028B1 (en) * | 2007-12-20 | 2016-03-09 | Butamax (TM) Advanced Biofuels LLC | Ketol-acid reductoisomerase using NADH |
| US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| CN101952448A (zh) | 2007-12-23 | 2011-01-19 | 格沃股份有限公司 | 高产率产生异丁醇的酵母生物 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| WO2009143455A2 (en) | 2008-05-22 | 2009-11-26 | Microbia, Inc. | Engineering resistance to aliphatic alcohols |
| US8637281B2 (en) | 2008-09-29 | 2014-01-28 | Butamax(Tm) Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| EP2821484B1 (en) | 2008-09-29 | 2016-06-29 | Butamax Advanced Biofuels LLC | Identification and use of Bacterial [2Fe-2S] dihydroxy-acid dehydratases |
| CA2735948A1 (en) | 2008-09-29 | 2011-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| EP2342330A1 (en) | 2008-09-29 | 2011-07-13 | Butamax Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| MX2011003313A (es) | 2008-09-29 | 2011-06-16 | Butamax Tm Advanced Biofuels | Actividad enzimatica de fe-s heterologa aumentada en levadura. |
| AU2009320163B2 (en) | 2008-10-27 | 2014-10-02 | Butamax(Tm) Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
| BRPI0921734A2 (pt) | 2008-10-31 | 2019-01-08 | California Inst Of Techn | micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
| US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| EP2464736A4 (en) | 2009-08-12 | 2013-07-31 | Gevo Inc | PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL |
| JP5805094B2 (ja) | 2009-09-29 | 2015-11-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 高有効性のケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生産 |
| US9260708B2 (en) | 2009-09-29 | 2016-02-16 | Butamax Advanced Biofuels Llc | Yeast production host cells |
| JP2013505739A (ja) | 2009-09-29 | 2013-02-21 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 乳酸菌におけるアセト乳酸誘導生成物への改善されたフラックス |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| GB2487889B (en) | 2009-11-24 | 2012-12-19 | Gevo Inc | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| KR20120099509A (ko) | 2009-12-29 | 2012-09-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 재조합 숙주 세포에서 육탄당 키나아제의 발현 |
| CN102869763A (zh) | 2010-02-12 | 2013-01-09 | 格沃股份有限公司 | 用于提高燃料、化学品和氨基酸产生的副产物蓄积减少的酵母微生物 |
| WO2011103300A2 (en) | 2010-02-17 | 2011-08-25 | Butamax(Tm) Advanced Biofuels Llc | Improving activity of fe-s cluster requiring proteins |
| AU2011268326B2 (en) | 2010-06-17 | 2015-02-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| EP2614138B1 (en) | 2010-09-07 | 2017-08-30 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
| US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
| BR112013032320A2 (pt) | 2011-06-17 | 2016-12-20 | Butamax Advanced Biofuels Llc | método e composição de produção de butanol, composição de butanol e isobutanol, método de cultivo de um micro-organismo produtor de butanol em material lignocelulósico e método para inibir o crescimento de micro-organismos que não produzem butanol em uma composição |
| US9238828B2 (en) | 2011-07-28 | 2016-01-19 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
| AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| JP2015510774A (ja) | 2012-03-23 | 2015-04-13 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ブタノール産生菌用培地の酢酸補給 |
| AU2013266727A1 (en) | 2012-05-11 | 2014-11-06 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| JP6407869B2 (ja) | 2012-09-26 | 2018-10-17 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトール酸レダクトイソメラーゼ活性を有するポリペプチド |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
-
2013
- 2013-05-10 AU AU2013266727A patent/AU2013266727A1/en not_active Abandoned
- 2013-05-10 WO PCT/US2013/040627 patent/WO2013176909A2/en not_active Ceased
- 2013-05-10 JP JP2015511775A patent/JP6321631B2/ja active Active
- 2013-05-10 CN CN201380036539.6A patent/CN104619835B/zh not_active Expired - Fee Related
- 2013-05-10 BR BR112014028153-0A patent/BR112014028153A2/pt not_active Application Discontinuation
- 2013-05-10 KR KR1020147034485A patent/KR20150014953A/ko not_active Withdrawn
- 2013-05-10 MX MX2018004620A patent/MX370134B/es unknown
- 2013-05-10 NZ NZ701099A patent/NZ701099A/en not_active IP Right Cessation
- 2013-05-10 MX MX2014013446A patent/MX2014013446A/es unknown
- 2013-05-10 EP EP13742293.7A patent/EP2847326A2/en not_active Withdrawn
- 2013-05-10 US US13/891,963 patent/US9169467B2/en active Active
- 2013-05-10 CA CA2873109A patent/CA2873109A1/en not_active Abandoned
-
2014
- 2014-10-23 ZA ZA2014/07713A patent/ZA201407713B/en unknown
-
2015
- 2015-09-14 US US14/853,108 patent/US9388392B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ701099A (en) | 2017-04-28 |
| US20160032255A1 (en) | 2016-02-04 |
| US20140051133A1 (en) | 2014-02-20 |
| CN104619835A (zh) | 2015-05-13 |
| CA2873109A1 (en) | 2013-11-28 |
| EP2847326A2 (en) | 2015-03-18 |
| US9169467B2 (en) | 2015-10-27 |
| AU2013266727A1 (en) | 2014-11-06 |
| ZA201407713B (en) | 2016-05-25 |
| JP2015517310A (ja) | 2015-06-22 |
| JP6321631B2 (ja) | 2018-05-09 |
| WO2013176909A3 (en) | 2014-02-13 |
| CN104619835B (zh) | 2018-06-19 |
| MX2014013446A (es) | 2014-12-08 |
| US9388392B2 (en) | 2016-07-12 |
| BR112014028153A2 (pt) | 2018-05-08 |
| KR20150014953A (ko) | 2015-02-09 |
| WO2013176909A2 (en) | 2013-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ701099A (en) | Ketol-acid reductoisomerase enzymes and methods of use | |
| EP4559918A3 (en) | Glucosylceramide synthase inhibitors | |
| TN2015000091A1 (en) | Glucosylceramide synthase inhibitors | |
| WO2012104007A3 (de) | 7-azaindolderivate | |
| CL2013000238A1 (es) | Uso de inhibores de la succinato deshidrogenasa y/o inhibidores del complejo iii para mejorar la relacion entre microorganismos dañinos y beneficiosos. | |
| IN2014CN02100A (enExample) | ||
| IN2014MN00989A (enExample) | ||
| BR112014024675A8 (pt) | célula hospedeira recombinante, cultura celular | |
| EP2723263A4 (en) | SYSTEMS, DEVICES, AND METHODS FOR INDUCING PROGRAMMED CELL DEATH OF ADIPOSE TISSUES | |
| NZ606589A (en) | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof | |
| EP4582090A3 (en) | Composition comprising pegylated arginine deiminase | |
| EP2880050A4 (en) | NOVEL ENZYMES, ENZYME COMPONENTS AND USES THEREOF | |
| ZA201208522B (en) | Methods for measuring enzyme activity useful in determining cell viability in non-purified sapmles | |
| SG10201804952QA (en) | Glucosylceramide synthase inhibitors | |
| PH12014500234A1 (en) | Endogenous dnase activity to reduce dna content | |
| MX2015012842A (es) | Prodecimiento para preparar inhibidores de la glucosilceramida sintasa. | |
| EP3049529A4 (en) | Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same | |
| EP2841408A4 (en) | METHODS OF MAINTAINING AND IMPROVING CELL BIOLOGICAL FUNCTION AND ACTIVITY | |
| TN2013000368A1 (en) | Glucosylceramide synthase inhibitors | |
| UA55887U (ru) | Способ диагностики риска прогрессии гиперплазии эндометрия в передрак и рак эндометрия | |
| SG10201602155XA (en) | Cleavable cellulosic sponge development for 3 dimensional cell culture and spheroids retrieval | |
| SG2012070058A (en) | Cleavable cellulosic sponge development for 3 dimensional cell culture and spheroids retrieval | |
| HK1197820A (en) | Macrocyclic insulin-degrading enzyme (ide) inhibitors and uses thereof | |
| PL392127A1 (pl) | Podłoże do hodowli komórek, jego zastosowanie oraz sposób in vitro hodowli komórek ludzkich lub zwierzęcych |