MX367578B - Proceso para producir derivado de diazabiciclooctano y su intermediario. - Google Patents
Proceso para producir derivado de diazabiciclooctano y su intermediario.Info
- Publication number
- MX367578B MX367578B MX2016003867A MX2016003867A MX367578B MX 367578 B MX367578 B MX 367578B MX 2016003867 A MX2016003867 A MX 2016003867A MX 2016003867 A MX2016003867 A MX 2016003867A MX 367578 B MX367578 B MX 367578B
- Authority
- MX
- Mexico
- Prior art keywords
- production method
- intermediary body
- diazabicyclooctane derivative
- isoindole
- dioxo
- Prior art date
Links
- NFDXQGNDWIPXQL-UHFFFAOYSA-N 1-cyclooctyldiazocane Chemical class C1CCCCCCC1N1NCCCCCC1 NFDXQGNDWIPXQL-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- -1 2,5-dioxopyrrolidine-1-yl Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013197110 | 2013-09-24 | ||
| PCT/JP2014/075203 WO2015046207A1 (ja) | 2013-09-24 | 2014-09-24 | ジアザビシクロオクタン誘導体の製造法とその中間体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016003867A MX2016003867A (es) | 2016-08-04 |
| MX367578B true MX367578B (es) | 2019-08-27 |
Family
ID=52743343
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016003867A MX367578B (es) | 2013-09-24 | 2014-09-24 | Proceso para producir derivado de diazabiciclooctano y su intermediario. |
| MX2019006550A MX372585B (es) | 2013-09-24 | 2014-09-24 | Proceso para producir derivado de diazabiciclooctano y su intermediario |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019006550A MX372585B (es) | 2013-09-24 | 2014-09-24 | Proceso para producir derivado de diazabiciclooctano y su intermediario |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10000491B2 (enExample) |
| EP (1) | EP3050883B1 (enExample) |
| JP (1) | JP6453222B2 (enExample) |
| KR (1) | KR102239725B1 (enExample) |
| CN (2) | CN107501264A (enExample) |
| AR (5) | AR097744A1 (enExample) |
| AU (1) | AU2014324302B2 (enExample) |
| BR (1) | BR112016006246B8 (enExample) |
| CA (1) | CA2924953C (enExample) |
| DK (1) | DK3050883T3 (enExample) |
| ES (1) | ES2793201T3 (enExample) |
| HK (1) | HK1244487A1 (enExample) |
| HU (1) | HUE049027T2 (enExample) |
| IL (1) | IL244740B (enExample) |
| MX (2) | MX367578B (enExample) |
| MY (2) | MY193210A (enExample) |
| NZ (1) | NZ718009A (enExample) |
| RU (1) | RU2719480C2 (enExample) |
| SG (1) | SG11201602256UA (enExample) |
| TW (1) | TWI644908B (enExample) |
| WO (1) | WO2015046207A1 (enExample) |
| ZA (1) | ZA201602053B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY174523A (en) * | 2012-05-30 | 2020-04-23 | Meiji Seika Pharma Co Ltd | ?-lactamase inhibitor and process for preparing the same |
| MY193210A (en) | 2013-09-24 | 2022-09-26 | Meiji Seika Pharma Co Ltd | Process for producing diazabicyclooctane derivative |
| WO2015053297A1 (ja) * | 2013-10-08 | 2015-04-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ジアザビシクロオクタン誘導体の結晶とその製造法 |
| ES2821826T3 (es) | 2014-12-05 | 2021-04-27 | Meiji Seika Pharma Co Ltd | Método para producir cristales de derivado de diazabiciclooctano y preparación liofilizada estable |
| CA2944306C (en) | 2015-10-30 | 2023-11-14 | The Toronto-Dominion Bank | Validating encrypted data from a multi-layer token |
| US11216808B2 (en) | 2015-11-04 | 2022-01-04 | The Toronto-Dominion Bank | Token-based system for excising data from databases |
| JP2020011901A (ja) * | 2016-10-20 | 2020-01-23 | 協和キリン株式会社 | ピロリジン化合物の製造方法 |
| CN106699756B (zh) * | 2016-12-30 | 2019-10-29 | 淄博鑫泉医药技术服务有限公司 | β内酰胺酶抑制剂阿维巴坦的合成方法 |
| WO2019064071A1 (en) | 2017-09-27 | 2019-04-04 | F. Hoffmann-La Roche Ag | CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF |
| CN111447924A (zh) | 2017-09-27 | 2020-07-24 | 费多拉制药公司 | 二氮杂二环辛烷衍生物的药物形式及其制备方法 |
| US10584123B2 (en) | 2017-09-27 | 2020-03-10 | Fedora Pharmaceuticals Inc. | Pharmaceutical forms of diazabicyclooctane derivatives and manufacturing method thereof |
| CN109678856B (zh) * | 2017-10-18 | 2020-09-25 | 新发药业有限公司 | 一种阿维巴坦中间体的制备方法 |
| WO2019101722A1 (en) | 2017-11-23 | 2019-05-31 | F. Hoffmann-La Roche Ag | Proline hydroxylases as well as uses, methods and products involving the same |
| WO2020018462A1 (en) | 2018-07-16 | 2020-01-23 | Brown University | A chromogenic beta-lactamase substrate |
| CN119707784A (zh) * | 2018-09-21 | 2025-03-28 | 株式会社Api | 氨基酸衍生物的制备方法 |
| US12195755B2 (en) | 2019-05-20 | 2025-01-14 | Brown University | Placental lipid bilayer for cell-free molecular interaction studies |
| WO2021038403A1 (en) | 2019-08-30 | 2021-03-04 | DePuy Synthes Products, Inc. | Electrical device for monitoring, prevention, and treatment of implant infections |
| CN121021508A (zh) * | 2025-10-29 | 2025-11-28 | 北京耀诚惠仁科技有限公司 | β-内酰胺酶抑制剂中间体共晶或盐及其制备方法和应用 |
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| JPS6019759B2 (ja) | 1977-11-24 | 1985-05-17 | イ−ライ・リリ−・アンド・カンパニ− | 非経口投予用１１１１５１５２１３９１９９東京都中央区京橋２丁目３番１３号 |
| GB1589317A (en) | 1977-11-24 | 1981-05-13 | Lilly Co Eli | Freeze drying cephalothin sodium |
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| FR2815420B1 (fr) | 2000-10-16 | 2003-05-16 | Cit Alcatel | Compensation de la dispersion chromatique dans un systeme de transmission a fibre optique, et fibre de compensation |
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| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
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| US8772490B2 (en) | 2010-12-22 | 2014-07-08 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivatives and process for preparing the same |
| JP6023800B2 (ja) | 2011-06-17 | 2016-11-09 | アストラゼネカ アクチボラグ | ｔｒａｎｓ−７−オキソ−６−（スルホオキシ）−１，６−ジアザビシクロ［３，２，１］オクタン−２−カルボキサミドとその塩が含まれる複素環式化合物を製造するための方法 |
| CA2833241C (en) | 2011-08-27 | 2015-05-12 | Wockhardt Limited | 1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections |
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| US8754102B2 (en) | 2011-09-13 | 2014-06-17 | Wockhardt Ltd. | Nitrogen containing compounds and their use |
| US9505761B2 (en) | 2011-12-02 | 2016-11-29 | Fedora Pharmaceuticals Inc. | Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors |
| US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| MY174523A (en) | 2012-05-30 | 2020-04-23 | Meiji Seika Pharma Co Ltd | ?-lactamase inhibitor and process for preparing the same |
| MY193210A (en) | 2013-09-24 | 2022-09-26 | Meiji Seika Pharma Co Ltd | Process for producing diazabicyclooctane derivative |
| WO2015053297A1 (ja) * | 2013-10-08 | 2015-04-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ジアザビシクロオクタン誘導体の結晶とその製造法 |
-
2014
- 2014-09-24 MY MYPI2019004461A patent/MY193210A/en unknown
- 2014-09-24 MX MX2016003867A patent/MX367578B/es active IP Right Grant
- 2014-09-24 EP EP14847854.8A patent/EP3050883B1/en active Active
- 2014-09-24 MX MX2019006550A patent/MX372585B/es unknown
- 2014-09-24 MY MYPI2016700980A patent/MY176278A/en unknown
- 2014-09-24 TW TW103132937A patent/TWI644908B/zh active
- 2014-09-24 HU HUE14847854A patent/HUE049027T2/hu unknown
- 2014-09-24 SG SG11201602256UA patent/SG11201602256UA/en unknown
- 2014-09-24 JP JP2015539238A patent/JP6453222B2/ja active Active
- 2014-09-24 KR KR1020167009769A patent/KR102239725B1/ko active Active
- 2014-09-24 CN CN201710665418.8A patent/CN107501264A/zh active Pending
- 2014-09-24 BR BR112016006246A patent/BR112016006246B8/pt active IP Right Grant
- 2014-09-24 US US15/023,976 patent/US10000491B2/en active Active
- 2014-09-24 AU AU2014324302A patent/AU2014324302B2/en active Active
- 2014-09-24 WO PCT/JP2014/075203 patent/WO2015046207A1/ja not_active Ceased
- 2014-09-24 AR ARP140103525A patent/AR097744A1/es active IP Right Grant
- 2014-09-24 RU RU2016115767A patent/RU2719480C2/ru active
- 2014-09-24 CN CN201480052097.9A patent/CN105555787B/zh active Active
- 2014-09-24 ES ES14847854T patent/ES2793201T3/es active Active
- 2014-09-24 NZ NZ718009A patent/NZ718009A/en unknown
- 2014-09-24 DK DK14847854.8T patent/DK3050883T3/da active
- 2014-09-24 CA CA2924953A patent/CA2924953C/en active Active
-
2016
- 2016-03-23 IL IL244740A patent/IL244740B/en active IP Right Grant
- 2016-03-29 ZA ZA2016/02053A patent/ZA201602053B/en unknown
- 2016-06-24 HK HK18103950.2A patent/HK1244487A1/zh unknown
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2017
- 2017-06-05 US US15/613,620 patent/US10000492B2/en active Active
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2023
- 2023-11-28 AR ARP230103207A patent/AR131188A2/es unknown
- 2023-11-28 AR ARP230103205A patent/AR131186A2/es unknown
- 2023-11-28 AR ARP230103208A patent/AR131189A2/es unknown
- 2023-11-28 AR ARP230103209A patent/AR131190A2/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |