HK1219473A1 - 二氮雜二環辛烷衍生物的製備方法及其中間體 - Google Patents
二氮雜二環辛烷衍生物的製備方法及其中間體Info
- Publication number
- HK1219473A1 HK1219473A1 HK16107390.3A HK16107390A HK1219473A1 HK 1219473 A1 HK1219473 A1 HK 1219473A1 HK 16107390 A HK16107390 A HK 16107390A HK 1219473 A1 HK1219473 A1 HK 1219473A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- production method
- intermediary body
- diazabicyclooctane derivative
- diazabicyclooctane
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013197110 | 2013-09-24 | ||
PCT/JP2014/075203 WO2015046207A1 (ja) | 2013-09-24 | 2014-09-24 | ジアザビシクロオクタン誘導体の製造法とその中間体 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1219473A1 true HK1219473A1 (zh) | 2017-04-07 |
Family
ID=52743343
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16107390.3A HK1219473A1 (zh) | 2013-09-24 | 2016-06-24 | 二氮雜二環辛烷衍生物的製備方法及其中間體 |
HK18103950.2A HK1244487A1 (zh) | 2013-09-24 | 2016-06-24 | 二氮雜二環辛烷衍生物的製備方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103950.2A HK1244487A1 (zh) | 2013-09-24 | 2016-06-24 | 二氮雜二環辛烷衍生物的製備方法 |
Country Status (22)
Country | Link |
---|---|
US (2) | US10000491B2 (zh) |
EP (1) | EP3050883B1 (zh) |
JP (1) | JP6453222B2 (zh) |
KR (1) | KR102239725B1 (zh) |
CN (2) | CN105555787B (zh) |
AR (1) | AR097744A1 (zh) |
AU (1) | AU2014324302B2 (zh) |
BR (1) | BR112016006246B8 (zh) |
CA (1) | CA2924953C (zh) |
DK (1) | DK3050883T3 (zh) |
ES (1) | ES2793201T3 (zh) |
HK (2) | HK1219473A1 (zh) |
HU (1) | HUE049027T2 (zh) |
IL (1) | IL244740B (zh) |
MX (1) | MX367578B (zh) |
MY (2) | MY193210A (zh) |
NZ (1) | NZ718009A (zh) |
RU (1) | RU2719480C2 (zh) |
SG (1) | SG11201602256UA (zh) |
TW (1) | TWI644908B (zh) |
WO (1) | WO2015046207A1 (zh) |
ZA (1) | ZA201602053B (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX366948B (es) | 2012-05-30 | 2019-07-30 | Meiji Seika Pharma Co Ltd | Nuevo inhibidor de beta-lactamasa y proceso para prepararlo. |
ES2793201T3 (es) | 2013-09-24 | 2020-11-13 | Meiji Seika Pharma Co Ltd | Procedimiento de producción de derivados y productos intermedios de diazabiciclooctano |
AR097971A1 (es) * | 2013-10-08 | 2016-04-20 | Meiji Seika Pharma Co Ltd | Formas cristalinas de derivado de diazabiciclooctano y proceso de producción de ellas |
CN107001366B (zh) * | 2014-12-05 | 2020-08-28 | 明治制果药业株式会社 | 二氮杂二环辛烷衍生物的结晶以及稳定的冻干制剂的制备方法 |
CA2944306C (en) | 2015-10-30 | 2023-11-14 | The Toronto-Dominion Bank | Validating encrypted data from a multi-layer token |
US11216808B2 (en) | 2015-11-04 | 2022-01-04 | The Toronto-Dominion Bank | Token-based system for excising data from databases |
JP2020011901A (ja) * | 2016-10-20 | 2020-01-23 | 協和キリン株式会社 | ピロリジン化合物の製造方法 |
CN106699756B (zh) * | 2016-12-30 | 2019-10-29 | 淄博鑫泉医药技术服务有限公司 | β内酰胺酶抑制剂阿维巴坦的合成方法 |
KR20200091394A (ko) | 2017-09-27 | 2020-07-30 | 페도라 파마슈티칼스 인코포레이티드 | 디아자비시클로옥탄 유도체의 약제학적 형태 및 그의 제조방법 |
EP3687504A1 (en) | 2017-09-27 | 2020-08-05 | Fedora Pharmaceuticals Inc. | Pharmaceutical forms of diazabicyclooctane derivatives and process for producing the same |
EP3687992A1 (en) | 2017-09-27 | 2020-08-05 | Meiji Seika Pharma Co., Ltd. | Crystalline forms of diazabicyclooctane derivatives and production process thereof |
CN109678856B (zh) * | 2017-10-18 | 2020-09-25 | 新发药业有限公司 | 一种阿维巴坦中间体的制备方法 |
EP3714046A1 (en) | 2017-11-23 | 2020-09-30 | H. Hoffnabb-La Roche Ag | Proline hydroxylases as well as uses, methods and products involving the same |
US11957690B2 (en) | 2018-07-16 | 2024-04-16 | Brown University | Chromogenic beta-lactamase substrate |
US11897844B2 (en) * | 2018-09-21 | 2024-02-13 | Api Corporation | Method for producing amino acid derivatives |
WO2021038403A1 (en) | 2019-08-30 | 2021-03-04 | DePuy Synthes Products, Inc. | Electrical device for monitoring, prevention, and treatment of implant infections |
Family Cites Families (33)
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JPS5038509B1 (zh) | 1970-10-21 | 1975-12-10 | ||
JPS538509A (en) | 1976-07-13 | 1978-01-26 | Toshiba Corp | Impedance matching system for data transmission circuit |
JPS6019759B2 (ja) | 1977-11-24 | 1985-05-17 | イ−ライ・リリ−・アンド・カンパニ− | 非経口投予用11115152139199東京都中央区京橋2丁目3番13号 |
GB1589317A (en) | 1977-11-24 | 1981-05-13 | Lilly Co Eli | Freeze drying cephalothin sodium |
JPS60255723A (ja) | 1984-05-31 | 1985-12-17 | Ono Pharmaceut Co Ltd | メシル酸ガベキサートの結晶性凍結乾燥製剤及びその製造方法 |
JPH07117533B2 (ja) | 1985-08-28 | 1995-12-18 | 株式会社生体科学研究所 | トランスフエリンおよびその用途 |
US20030220521A1 (en) | 1989-07-27 | 2003-11-27 | G.D. Searle & Co. | Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension |
TW264475B (zh) | 1991-09-20 | 1995-12-01 | Takeda Pharm Industry Co Ltd | |
US5854239A (en) * | 1993-12-29 | 1998-12-29 | Pfizer Inc. | Diazabicyclic neuokinin antagonists |
ATE223916T1 (de) | 1994-05-02 | 2002-09-15 | Shionogi & Co | Kristalline pyrrolidylthiocarbapenem derivate, lyophilisierste präparationen dieser kristalle und verfahren zu deren herstellung |
JP2843444B2 (ja) | 1994-05-02 | 1999-01-06 | 塩野義製薬株式会社 | ピロリジルチオカルバペネム誘導体の結晶,該結晶を含む凍結乾燥製剤,およびその製造方法 |
FR2812635B1 (fr) | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
FR2815420B1 (fr) | 2000-10-16 | 2003-05-16 | Cit Alcatel | Compensation de la dispersion chromatique dans un systeme de transmission a fibre optique, et fibre de compensation |
FR2825705B1 (fr) | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
FR2921060B1 (fr) | 2007-09-14 | 2012-06-15 | Novexel | Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires |
ES2533826T3 (es) | 2008-01-18 | 2015-04-15 | Merck Sharp & Dohme Corp. | Inhibidores de beta-lactamasa |
FR2930553B1 (fr) | 2008-04-29 | 2010-05-21 | Novexel | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases |
FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
US20120053350A1 (en) | 2009-04-30 | 2012-03-01 | Ian Mangion | Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids |
FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
JP2012122603A (ja) | 2010-11-15 | 2012-06-28 | Nifco Inc | コネクタ装置 |
US8772490B2 (en) | 2010-12-22 | 2014-07-08 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivatives and process for preparing the same |
CN104892490B (zh) * | 2010-12-22 | 2017-07-21 | 明治制果药业株式会社 | 用于制备光学活性二氮杂环辛烷衍生物的中间体化合物的化合物 |
MX361020B (es) | 2011-06-17 | 2018-11-26 | Pfizer Anti Infectives Ab | Procesos para preparar compuestos heterociclicos, incluida trans-7-oxo-6-(sulfooxi)-1,6-diazabiciclo [3,2,1]octano-2-carboxam ida y sales de la misma. |
RU2578370C2 (ru) | 2011-08-27 | 2016-03-27 | Вокхардт Лимитед | Производные 1,6- диазабицикло [3,2,1] октан-7-она и их применение при лечении бактериальных инфекционных болезней |
PT2872510T (pt) | 2011-08-30 | 2017-03-01 | Wockhardt Ltd | Derivados de 1,6-diazabiciclo[3,2,1]octan-7-ona e seu uso no tratamento de infeções bacterianas |
RU2569307C1 (ru) | 2011-09-13 | 2015-11-20 | Вокхардт Лимитед | Азотсодержащие соединения и их применение |
US9505761B2 (en) | 2011-12-02 | 2016-11-29 | Fedora Pharmaceuticals Inc. | Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors |
US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
MX366948B (es) * | 2012-05-30 | 2019-07-30 | Meiji Seika Pharma Co Ltd | Nuevo inhibidor de beta-lactamasa y proceso para prepararlo. |
ES2793201T3 (es) | 2013-09-24 | 2020-11-13 | Meiji Seika Pharma Co Ltd | Procedimiento de producción de derivados y productos intermedios de diazabiciclooctano |
AR097971A1 (es) * | 2013-10-08 | 2016-04-20 | Meiji Seika Pharma Co Ltd | Formas cristalinas de derivado de diazabiciclooctano y proceso de producción de ellas |
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2014
- 2014-09-24 ES ES14847854T patent/ES2793201T3/es active Active
- 2014-09-24 TW TW103132937A patent/TWI644908B/zh active
- 2014-09-24 WO PCT/JP2014/075203 patent/WO2015046207A1/ja active Application Filing
- 2014-09-24 MY MYPI2019004461A patent/MY193210A/en unknown
- 2014-09-24 CN CN201480052097.9A patent/CN105555787B/zh active Active
- 2014-09-24 HU HUE14847854A patent/HUE049027T2/hu unknown
- 2014-09-24 SG SG11201602256UA patent/SG11201602256UA/en unknown
- 2014-09-24 KR KR1020167009769A patent/KR102239725B1/ko active IP Right Grant
- 2014-09-24 AR ARP140103525A patent/AR097744A1/es active IP Right Grant
- 2014-09-24 AU AU2014324302A patent/AU2014324302B2/en active Active
- 2014-09-24 MY MYPI2016700980A patent/MY176278A/en unknown
- 2014-09-24 US US15/023,976 patent/US10000491B2/en active Active
- 2014-09-24 CA CA2924953A patent/CA2924953C/en active Active
- 2014-09-24 EP EP14847854.8A patent/EP3050883B1/en active Active
- 2014-09-24 NZ NZ718009A patent/NZ718009A/en unknown
- 2014-09-24 DK DK14847854.8T patent/DK3050883T3/da active
- 2014-09-24 CN CN201710665418.8A patent/CN107501264A/zh active Pending
- 2014-09-24 MX MX2016003867A patent/MX367578B/es active IP Right Grant
- 2014-09-24 BR BR112016006246A patent/BR112016006246B8/pt active IP Right Grant
- 2014-09-24 JP JP2015539238A patent/JP6453222B2/ja active Active
- 2014-09-24 RU RU2016115767A patent/RU2719480C2/ru active
-
2016
- 2016-03-23 IL IL244740A patent/IL244740B/en active IP Right Grant
- 2016-03-29 ZA ZA2016/02053A patent/ZA201602053B/en unknown
- 2016-06-24 HK HK16107390.3A patent/HK1219473A1/zh unknown
- 2016-06-24 HK HK18103950.2A patent/HK1244487A1/zh unknown
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2017
- 2017-06-05 US US15/613,620 patent/US10000492B2/en active Active
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