MX365061B - Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. - Google Patents

Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Info

Publication number
MX365061B
MX365061B MX2015015561A MX2015015561A MX365061B MX 365061 B MX365061 B MX 365061B MX 2015015561 A MX2015015561 A MX 2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A MX 365061 B MX365061 B MX 365061B
Authority
MX
Mexico
Prior art keywords
kidney function
methods
biomarkers
same
kidney
Prior art date
Application number
MX2015015561A
Other languages
English (en)
Spanish (es)
Other versions
MX2015015561A (es
Inventor
V Brown Meredith
Perichon Regis
Edmond Cobb Jeffery
Kennedy Adam
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Publication of MX2015015561A publication Critical patent/MX2015015561A/es
Publication of MX365061B publication Critical patent/MX365061B/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2015015561A 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. MX365061B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14
PCT/US2014/037762 WO2014186311A1 (en) 2013-05-14 2014-05-13 Biomarkers related to kidney function and methods using the same

Publications (2)

Publication Number Publication Date
MX2015015561A MX2015015561A (es) 2016-02-05
MX365061B true MX365061B (es) 2019-05-22

Family

ID=51898805

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015015561A MX365061B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.
MX2019005748A MX391220B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019005748A MX391220B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Country Status (10)

Country Link
US (2) US10539575B2 (enExample)
EP (3) EP3546940B1 (enExample)
JP (1) JP6595984B2 (enExample)
CN (2) CN110196335A (enExample)
AU (1) AU2014265669B2 (enExample)
BR (1) BR112015028253A2 (enExample)
CA (2) CA3184836A1 (enExample)
ES (2) ES2871823T3 (enExample)
MX (2) MX365061B (enExample)
WO (1) WO2014186311A1 (enExample)

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WO2014186311A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same
CN111879948A (zh) 2013-10-17 2020-11-03 综合医院公司 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物
CA2973116C (en) * 2015-01-09 2023-08-15 Global Genomics Group, LLC Blood based biomarkers for diagnosing atherosclerotic coronary artery disease
US20180003721A1 (en) * 2015-01-15 2018-01-04 Joslin Diabetes Center Metabolite Biomarkers Predictive Of Renal Disease In Diabetic Patients
EP3355914B1 (en) 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
ES2891088T3 (es) * 2016-07-28 2022-01-26 Metabolon Inc Métodos de diagnóstico, agentes terapéuticos y usos de los mismos
EP3552022B1 (en) * 2016-11-25 2021-06-09 Implexion AB Metabolic disorders
WO2018118630A1 (en) 2016-12-19 2018-06-28 Metabolon, Inc. Mass spectrometry assay method for detection and quantitation of kidney function metabolites
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
AU2018313853A1 (en) 2017-08-08 2020-01-02 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
CA3077029A1 (en) * 2017-09-28 2019-04-04 Metabolon, Inc. Compounds, reagents, and uses thereof
EP3740760B1 (en) * 2018-01-19 2023-05-31 Mars, Incorporated Biomarkers and classification algorithms for chronic kidney disease in cats
WO2020018463A1 (en) * 2018-07-14 2020-01-23 Mars, Incorporated Biomarkers and test models for chronic kidney disease
JP7205940B2 (ja) * 2019-02-20 2023-01-17 株式会社パートナーファーム 固相反応チップ及びこれを用いた測定方法
CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
WO2021018774A1 (en) * 2019-07-26 2021-02-04 Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) Ergothioneine, s-methyl-ergothioneine, and uses thereof
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

Family Cites Families (19)

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JPH02196787A (ja) * 1989-01-25 1990-08-03 Otsuka Pharmaceut Co Ltd シュードウリジン誘導体
JPH0661278B2 (ja) * 1990-09-18 1994-08-17 旭化成工業株式会社 ミオイノシトールの高感度定量法および定量用組成物
US5712084A (en) * 1995-09-08 1998-01-27 Research Corporation Technologies, Inc. Donor kidney viability test for improved preservation
CN101377492B (zh) 2007-08-29 2014-04-23 北京九强生物技术股份有限公司 胱抑素c测定试剂盒
CA2735590A1 (en) * 2008-08-29 2010-03-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
CA2743253A1 (en) * 2008-11-22 2010-05-27 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20100273207A1 (en) * 2009-04-24 2010-10-28 Raymond Langley Methods for Diagnosis of Sepsis and Risk of Death
JP5197846B2 (ja) 2009-04-30 2013-05-15 紀陽 田仲 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
WO2010144336A2 (en) * 2009-06-08 2010-12-16 Quark Pharmaceuticals, Inc. Methods for treating chronic kidney disease
WO2011027573A1 (ja) * 2009-09-04 2011-03-10 国立大学法人東北大学 ヒトにおける新たな腎疾患マーカー物質
NZ625423A (en) * 2009-12-20 2015-02-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US8980548B2 (en) * 2010-05-19 2015-03-17 Metabolon, Inc. Methods and reagents for metabolomics and histology in a biological sample and a kit for the same
JP5899213B2 (ja) * 2010-08-06 2016-04-06 マイカーティス エヌ.ヴェ.MyCartis NV 腎機能不全のバイオマーカーとしてのパールカン
JP5916058B2 (ja) * 2011-08-26 2016-05-11 国立大学法人東北大学 細胞ストレス状態のバイオマーカー
CN103814295B (zh) * 2011-09-14 2016-08-24 巴斯夫欧洲公司 用于评估肾毒性的手段和方法
WO2013048344A1 (en) * 2011-09-29 2013-04-04 National University Of Singapore Urinary metabolomic markers for renal insufficiency
WO2014186311A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same
ES2891088T3 (es) * 2016-07-28 2022-01-26 Metabolon Inc Métodos de diagnóstico, agentes terapéuticos y usos de los mismos

Also Published As

Publication number Publication date
MX2015015561A (es) 2016-02-05
EP2997366B1 (en) 2018-10-10
US20160116486A1 (en) 2016-04-28
CN110196335A (zh) 2019-09-03
ES2702123T3 (es) 2019-02-27
EP2997366A4 (en) 2017-04-12
MX2019005748A (es) 2019-08-12
CA3184836A1 (en) 2014-11-20
AU2014265669B2 (en) 2020-05-14
US10539575B2 (en) 2020-01-21
MX391220B (es) 2025-03-21
HK1218331A1 (zh) 2017-02-10
WO2014186311A1 (en) 2014-11-20
CA2911204C (en) 2023-03-28
CN105209909A (zh) 2015-12-30
HK1222905A1 (en) 2017-07-14
EP3546940A1 (en) 2019-10-02
US20200103417A1 (en) 2020-04-02
ES2871823T3 (es) 2021-11-02
CA2911204A1 (en) 2014-11-20
EP3546940B1 (en) 2021-02-17
AU2014265669A1 (en) 2015-12-24
BR112015028253A2 (pt) 2017-07-25
EP3410115A1 (en) 2018-12-05
EP2997366A1 (en) 2016-03-23
JP6595984B2 (ja) 2019-10-23
JP2016520192A (ja) 2016-07-11
CN105209909B (zh) 2019-06-07

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