ES2871823T3 - Biomarcadores relacionados con la función renal y métodos para utilizarlos - Google Patents

Biomarcadores relacionados con la función renal y métodos para utilizarlos Download PDF

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Publication number
ES2871823T3
ES2871823T3 ES19176215T ES19176215T ES2871823T3 ES 2871823 T3 ES2871823 T3 ES 2871823T3 ES 19176215 T ES19176215 T ES 19176215T ES 19176215 T ES19176215 T ES 19176215T ES 2871823 T3 ES2871823 T3 ES 2871823T3
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subject
level
ckd
acetylalanine
biomarkers
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ES19176215T
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English (en)
Spanish (es)
Inventor
Regis Perichon
Jeffery Cobb
Meredith Brown
Adam Kennedy
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Metabolon Inc
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Metabolon Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES19176215T 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos Active ES2871823T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14

Publications (1)

Publication Number Publication Date
ES2871823T3 true ES2871823T3 (es) 2021-11-02

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ID=51898805

Family Applications (2)

Application Number Title Priority Date Filing Date
ES19176215T Active ES2871823T3 (es) 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos
ES14797070T Active ES2702123T3 (es) 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14797070T Active ES2702123T3 (es) 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos

Country Status (10)

Country Link
US (2) US10539575B2 (enExample)
EP (3) EP3546940B1 (enExample)
JP (1) JP6595984B2 (enExample)
CN (2) CN110196335A (enExample)
AU (1) AU2014265669B2 (enExample)
BR (1) BR112015028253A2 (enExample)
CA (2) CA3184836A1 (enExample)
ES (2) ES2871823T3 (enExample)
MX (2) MX365061B (enExample)
WO (1) WO2014186311A1 (enExample)

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WO2014186311A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same
CN111879948A (zh) 2013-10-17 2020-11-03 综合医院公司 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物
CA2973116C (en) * 2015-01-09 2023-08-15 Global Genomics Group, LLC Blood based biomarkers for diagnosing atherosclerotic coronary artery disease
US20180003721A1 (en) * 2015-01-15 2018-01-04 Joslin Diabetes Center Metabolite Biomarkers Predictive Of Renal Disease In Diabetic Patients
EP3355914B1 (en) 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
ES2891088T3 (es) * 2016-07-28 2022-01-26 Metabolon Inc Métodos de diagnóstico, agentes terapéuticos y usos de los mismos
EP3552022B1 (en) * 2016-11-25 2021-06-09 Implexion AB Metabolic disorders
WO2018118630A1 (en) 2016-12-19 2018-06-28 Metabolon, Inc. Mass spectrometry assay method for detection and quantitation of kidney function metabolites
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
AU2018313853A1 (en) 2017-08-08 2020-01-02 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
CA3077029A1 (en) * 2017-09-28 2019-04-04 Metabolon, Inc. Compounds, reagents, and uses thereof
EP3740760B1 (en) * 2018-01-19 2023-05-31 Mars, Incorporated Biomarkers and classification algorithms for chronic kidney disease in cats
WO2020018463A1 (en) * 2018-07-14 2020-01-23 Mars, Incorporated Biomarkers and test models for chronic kidney disease
JP7205940B2 (ja) * 2019-02-20 2023-01-17 株式会社パートナーファーム 固相反応チップ及びこれを用いた測定方法
CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
WO2021018774A1 (en) * 2019-07-26 2021-02-04 Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) Ergothioneine, s-methyl-ergothioneine, and uses thereof
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

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JPH02196787A (ja) * 1989-01-25 1990-08-03 Otsuka Pharmaceut Co Ltd シュードウリジン誘導体
JPH0661278B2 (ja) * 1990-09-18 1994-08-17 旭化成工業株式会社 ミオイノシトールの高感度定量法および定量用組成物
US5712084A (en) * 1995-09-08 1998-01-27 Research Corporation Technologies, Inc. Donor kidney viability test for improved preservation
CN101377492B (zh) 2007-08-29 2014-04-23 北京九强生物技术股份有限公司 胱抑素c测定试剂盒
CA2735590A1 (en) * 2008-08-29 2010-03-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
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JP5197846B2 (ja) 2009-04-30 2013-05-15 紀陽 田仲 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
WO2010144336A2 (en) * 2009-06-08 2010-12-16 Quark Pharmaceuticals, Inc. Methods for treating chronic kidney disease
WO2011027573A1 (ja) * 2009-09-04 2011-03-10 国立大学法人東北大学 ヒトにおける新たな腎疾患マーカー物質
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Also Published As

Publication number Publication date
MX2015015561A (es) 2016-02-05
MX365061B (es) 2019-05-22
EP2997366B1 (en) 2018-10-10
US20160116486A1 (en) 2016-04-28
CN110196335A (zh) 2019-09-03
ES2702123T3 (es) 2019-02-27
EP2997366A4 (en) 2017-04-12
MX2019005748A (es) 2019-08-12
CA3184836A1 (en) 2014-11-20
AU2014265669B2 (en) 2020-05-14
US10539575B2 (en) 2020-01-21
MX391220B (es) 2025-03-21
HK1218331A1 (zh) 2017-02-10
WO2014186311A1 (en) 2014-11-20
CA2911204C (en) 2023-03-28
CN105209909A (zh) 2015-12-30
HK1222905A1 (en) 2017-07-14
EP3546940A1 (en) 2019-10-02
US20200103417A1 (en) 2020-04-02
CA2911204A1 (en) 2014-11-20
EP3546940B1 (en) 2021-02-17
AU2014265669A1 (en) 2015-12-24
BR112015028253A2 (pt) 2017-07-25
EP3410115A1 (en) 2018-12-05
EP2997366A1 (en) 2016-03-23
JP6595984B2 (ja) 2019-10-23
JP2016520192A (ja) 2016-07-11
CN105209909B (zh) 2019-06-07

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