MX357628B - Sistema y metodo para detectar proteinas amiloides. - Google Patents
Sistema y metodo para detectar proteinas amiloides.Info
- Publication number
- MX357628B MX357628B MX2013001537A MX2013001537A MX357628B MX 357628 B MX357628 B MX 357628B MX 2013001537 A MX2013001537 A MX 2013001537A MX 2013001537 A MX2013001537 A MX 2013001537A MX 357628 B MX357628 B MX 357628B
- Authority
- MX
- Mexico
- Prior art keywords
- amyloid
- binding compound
- eye
- amyloid protein
- bound
- Prior art date
Links
- 102000009091 Amyloidogenic Proteins Human genes 0.000 title abstract 7
- 108010048112 Amyloidogenic Proteins Proteins 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 5
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000003942 amyloidogenic effect Effects 0.000 abstract 1
- 230000010287 polarization Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/107—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining the shape or measuring the curvature of the cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
- A61B3/111—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils for measuring interpupillary distance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
- A61B3/1173—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes for examining the eye lens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0068—Confocal scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
- A61B5/6821—Eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0238—Optical sensor arrangements for performing transmission measurements on body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/13—Ophthalmic microscopes
- A61B3/135—Slit-lamp microscopes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Neurology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Developmental Disabilities (AREA)
- Child & Adolescent Psychology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37413110P | 2010-08-16 | 2010-08-16 | |
| US201061425490P | 2010-12-21 | 2010-12-21 | |
| EP11001148 | 2011-02-11 | ||
| PCT/US2011/047628 WO2012024188A1 (en) | 2010-08-16 | 2011-08-12 | System and method for detecting amyloid proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013001537A MX2013001537A (es) | 2013-06-05 |
| MX357628B true MX357628B (es) | 2018-07-17 |
Family
ID=44168199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013001537A MX357628B (es) | 2010-08-16 | 2011-08-12 | Sistema y metodo para detectar proteinas amiloides. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9220403B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2420179B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5863797B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101905436B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103153168B (cg-RX-API-DMAC7.html) |
| AR (1) | AR082707A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011292233B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013003754B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2807683C (cg-RX-API-DMAC7.html) |
| MX (1) | MX357628B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ607257A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2577810C2 (cg-RX-API-DMAC7.html) |
| SG (1) | SG188227A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI476392B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012024188A1 (cg-RX-API-DMAC7.html) |
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| ES2584512T3 (es) | 2008-03-27 | 2016-09-28 | Cognoptix, Inc. | Imágenes oculares para el diagnóstico de enfermedades neurodegenerativas |
| CN103153168B (zh) | 2010-08-16 | 2016-03-09 | 康格诺皮蒂克斯公司 | 用于探测淀粉样蛋白的系统和方法 |
| CA2834056A1 (en) * | 2011-04-27 | 2012-11-01 | Adlyfe, Inc. | Ocular detection of amyloid proteins |
| EP2788034B1 (en) | 2011-12-09 | 2021-05-26 | Regents of the University of Minnesota | Hyperspectral imaging for early detection of alzheimer's disease |
| US20130330711A1 (en) * | 2012-06-06 | 2013-12-12 | National Taiwan University | Sensor for detection of a target of interest |
| JP6133053B2 (ja) * | 2012-12-21 | 2017-05-24 | 浜松ホトニクス株式会社 | アミロイドの凝集体の定量方法及びその定量装置 |
| US20150042954A1 (en) * | 2013-08-08 | 2015-02-12 | University Of Rochester | System and Method for Fluorescence Lifetime Imaging Aided by Adaptive Optics |
| US20150065824A1 (en) * | 2013-08-28 | 2015-03-05 | Johnson & Johnson Vision Care, Inc. | Methods and apparatus to form ophthalmic devices incorporating fluorescence detectors |
| AR098232A1 (es) * | 2013-10-31 | 2016-05-18 | Cognoptix Inc | Métodos de preparación de una formulación oftálmica y usos de la misma |
| WO2015072964A1 (en) * | 2013-11-12 | 2015-05-21 | Cognoptix, Inc. | Method for measuring fluorescence in ocular tissue |
| CN103709069B (zh) * | 2014-01-07 | 2015-03-18 | 南方医科大学 | 一种6’-羟基萘基-2-氰基丙烯酸酯及其用途 |
| JP2017512834A (ja) * | 2014-03-19 | 2017-05-25 | アミディス・ダイアグノスティックス・インコーポレイテッド | アミロイド標的剤及びその使用方法 |
| JP2016014074A (ja) * | 2014-06-19 | 2016-01-28 | 国立研究開発法人物質・材料研究機構 | プログラム可能なナノロボットに添付されたセンサ、分子機械及びコントローラ |
| JP6550673B2 (ja) * | 2015-04-03 | 2019-07-31 | 国立大学法人 東京大学 | フォトルミネセンス寿命測定装置及び測定方法 |
| JP6832283B2 (ja) * | 2015-09-29 | 2021-02-24 | 浜松ホトニクス株式会社 | アミロイドβオリゴマーの検出方法、アミロイドβオリゴマー検出装置及びアミロイドβオリゴマー検出プログラム |
| WO2017156400A1 (en) | 2016-03-10 | 2017-09-14 | Regents Of The University Of Minnesota | Spectral-spatial imaging device |
| CA3031528A1 (en) * | 2016-08-01 | 2018-02-08 | Cognoptix, Inc. | System and method for detecting tau protein in ocular tissue |
| US10405785B2 (en) * | 2016-08-04 | 2019-09-10 | City University Of Hong Kong | Determination of a concentration of an analyte in a subject |
| CN109715045B (zh) * | 2016-09-16 | 2021-12-14 | 爱尔康公司 | 减影冠状面光学相干断层成像术成像 |
| US10905897B2 (en) * | 2016-10-20 | 2021-02-02 | Neuro-Laser Foundation, Inc. | Synergistic treatment methodologies using light therapy |
| US9950189B1 (en) * | 2016-10-20 | 2018-04-24 | Neuro-Laser Foundation Inc. | Treatment methodologies using light therapy |
| KR101835815B1 (ko) * | 2016-12-16 | 2018-03-07 | (주) 인텍플러스 | 형광수명 측정장치 및 측정방법 |
| US10631726B2 (en) * | 2017-01-11 | 2020-04-28 | Avedro, Inc. | Systems and methods for determining cross-linking distribution in a cornea and/or structural characteristics of a cornea |
| US11536731B2 (en) | 2017-01-23 | 2022-12-27 | Rensselaer Polytechnic Institute | Systems and methods for binding amyloid fibrils using fluorescent protein |
| JP7007132B2 (ja) * | 2017-08-09 | 2022-01-24 | 浜松ホトニクス株式会社 | アミロイド凝集体の検出方法、アミロイド凝集体検出装置、及びアミロイド凝集体検出プログラム |
| CA3082936A1 (en) | 2017-11-27 | 2019-05-31 | Retispec Inc. | Hyperspectral image-guided raman ocular imager for alzheimer's disease pathologies |
| CN108489941B (zh) * | 2018-01-31 | 2021-07-27 | 吉林大学 | 溴酚蓝在作为检测牛胰岛素淀粉样纤维探针和作为牛胰岛素淀粉样纤维抑制剂方面的应用 |
| WO2019232422A1 (en) * | 2018-05-31 | 2019-12-05 | Amydis, Inc. | Compositions and methods for detection of traumatic brain injury |
| US10746596B2 (en) * | 2018-06-18 | 2020-08-18 | Harry Owen | Probe optic light shields |
| JP7380013B2 (ja) * | 2019-09-26 | 2023-11-15 | 株式会社ニコン | 眼科装置、眼科装置の制御方法及びプログラム |
| WO2021192910A1 (ja) * | 2020-03-23 | 2021-09-30 | コニカミノルタ株式会社 | 画像生成方法、画像生成装置及びプログラム |
| GB2603006B (en) * | 2021-01-26 | 2024-07-03 | Edinburgh Biosciences Ltd | Apparatus and systems for monitoring and treating cataracts |
| SI4284230T1 (sl) * | 2021-01-26 | 2025-08-29 | Edinburgh Biosciences Limited | Naprava in sistemi za spremljanje in zdravljenje sive mrene |
| JP7633102B2 (ja) * | 2021-06-22 | 2025-02-19 | 浜松ホトニクス株式会社 | 蛍光寿命計測のバックグラウンド除去方法及び標的物質の定量方法 |
| KR102771665B1 (ko) * | 2021-11-30 | 2025-02-24 | 세종대학교산학협력단 | 다채널 형광 시상수 신호를 이용한 알츠하이머 지수 판단 장치 및 방법 |
| KR102784581B1 (ko) * | 2022-11-15 | 2025-03-19 | 가톨릭대학교 산학협력단 | 비침습적 알츠하이머 위험 검사장치 및 검사방법 |
| CN115855902B (zh) * | 2022-11-30 | 2025-10-03 | 西南交通大学 | 水体中磷酸三甲苯酯浓度的检测方法和检测材料 |
| EP4570166A1 (en) | 2023-12-12 | 2025-06-18 | Instytut Chemii Fizycznej Polskiej Akademii Nauk | System for photomultiplier protection in eye imaging |
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2011
- 2011-08-12 CN CN201180045350.4A patent/CN103153168B/zh not_active Expired - Fee Related
- 2011-08-12 EP EP11006656.0A patent/EP2420179B1/en not_active Not-in-force
- 2011-08-12 KR KR1020137006889A patent/KR101905436B1/ko not_active Expired - Fee Related
- 2011-08-12 EP EP11745903.2A patent/EP2605694B1/en active Active
- 2011-08-12 RU RU2013110796/14A patent/RU2577810C2/ru not_active IP Right Cessation
- 2011-08-12 MX MX2013001537A patent/MX357628B/es active IP Right Grant
- 2011-08-12 US US13/814,677 patent/US9220403B2/en not_active Expired - Fee Related
- 2011-08-12 WO PCT/US2011/047628 patent/WO2012024188A1/en not_active Ceased
- 2011-08-12 CA CA2807683A patent/CA2807683C/en not_active Expired - Fee Related
- 2011-08-12 NZ NZ607257A patent/NZ607257A/en not_active IP Right Cessation
- 2011-08-12 SG SG2013011531A patent/SG188227A1/en unknown
- 2011-08-12 BR BR112013003754-7A patent/BR112013003754B1/pt not_active IP Right Cessation
- 2011-08-12 JP JP2013524895A patent/JP5863797B2/ja not_active Expired - Fee Related
- 2011-08-12 AU AU2011292233A patent/AU2011292233B2/en not_active Ceased
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- 2011-08-16 AR ARP110102977A patent/AR082707A1/es not_active Application Discontinuation
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2015
- 2015-06-30 JP JP2015130669A patent/JP2015166749A/ja not_active Withdrawn
- 2015-12-01 US US14/955,853 patent/US9451909B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP5863797B2 (ja) | 2016-02-17 |
| WO2012024188A1 (en) | 2012-02-23 |
| AR082707A1 (es) | 2012-12-26 |
| RU2577810C2 (ru) | 2016-03-20 |
| CN103153168B (zh) | 2016-03-09 |
| EP2420179A3 (en) | 2012-03-21 |
| CN103153168A (zh) | 2013-06-12 |
| EP2420179B1 (en) | 2020-10-07 |
| US20160183859A1 (en) | 2016-06-30 |
| AU2011292233A1 (en) | 2013-03-07 |
| MX2013001537A (es) | 2013-06-05 |
| CA2807683C (en) | 2020-02-18 |
| KR20130138211A (ko) | 2013-12-18 |
| CA2807683A1 (en) | 2012-02-23 |
| BR112013003754B1 (pt) | 2021-11-09 |
| TW201215876A (en) | 2012-04-16 |
| JP2015166749A (ja) | 2015-09-24 |
| BR112013003754A2 (pt) | 2016-05-31 |
| AU2011292233B2 (en) | 2015-05-21 |
| US9451909B2 (en) | 2016-09-27 |
| US20130135580A1 (en) | 2013-05-30 |
| SG188227A1 (en) | 2013-04-30 |
| NZ607257A (en) | 2015-02-27 |
| JP2013534171A (ja) | 2013-09-02 |
| RU2013110796A (ru) | 2014-09-27 |
| EP2420179A2 (en) | 2012-02-22 |
| US9220403B2 (en) | 2015-12-29 |
| EP2605694A1 (en) | 2013-06-26 |
| TWI476392B (zh) | 2015-03-11 |
| EP2605694B1 (en) | 2021-10-27 |
| KR101905436B1 (ko) | 2018-10-08 |
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