MX357231B - Polipeptidos de anticuerpos que antagonizan el ligando cd40 (cd40l). - Google Patents

Polipeptidos de anticuerpos que antagonizan el ligando cd40 (cd40l).

Info

Publication number
MX357231B
MX357231B MX2014004293A MX2014004293A MX357231B MX 357231 B MX357231 B MX 357231B MX 2014004293 A MX2014004293 A MX 2014004293A MX 2014004293 A MX2014004293 A MX 2014004293A MX 357231 B MX357231 B MX 357231B
Authority
MX
Mexico
Prior art keywords
antibody polypeptides
cd40l
bind human
diseases
polypeptides
Prior art date
Application number
MX2014004293A
Other languages
English (en)
Other versions
MX2014004293A (es
Inventor
Suri Anish
Yamniuk Aaron
Grant Steven
Drew Philip
G Nadler Steven
K Tamura James
Price Laura
P Rehfuss Robert
J Suchard Suzanne
William Bryson James
Ignatovich Olga
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX357231(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX2014004293A publication Critical patent/MX2014004293A/es
Publication of MX357231B publication Critical patent/MX357231B/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Abstract

La presente invención se refiere a polipéptidos de anticuerpos que se fijan específicamente al CD40L humano. Una composición farmacéutica, caracterizada porque comprende una cantidad terapéuticamente eficaz del polipéptido de anticuerpos y un portador aceptable dese el punto de vista farmacéutico. Un polipéptido de anticuerpos para usarse en la antagonización de actividad de CD40L en un paciente con una enfermedad inmunitaria.
MX2014004293A 2011-10-13 2012-10-12 Polipeptidos de anticuerpos que antagonizan el ligando cd40 (cd40l). MX357231B (es)

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