MX357227B - Nanoparticulas basadas en lipidos. - Google Patents
Nanoparticulas basadas en lipidos.Info
- Publication number
- MX357227B MX357227B MX2013011231A MX2013011231A MX357227B MX 357227 B MX357227 B MX 357227B MX 2013011231 A MX2013011231 A MX 2013011231A MX 2013011231 A MX2013011231 A MX 2013011231A MX 357227 B MX357227 B MX 357227B
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- lipid
- based nanoparticles
- amyloid
- liposomal
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 5
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
- A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472605P | 2011-04-06 | 2011-04-06 | |
| PCT/US2012/032649 WO2012139080A2 (en) | 2011-04-06 | 2012-04-06 | Lipid-based nanoparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013011231A MX2013011231A (es) | 2015-03-05 |
| MX357227B true MX357227B (es) | 2018-07-02 |
Family
ID=46966277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013011231A MX357227B (es) | 2011-04-06 | 2012-04-06 | Nanoparticulas basadas en lipidos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9801957B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2694116B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6212032B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR101973063B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104144708B (cg-RX-API-DMAC7.html) |
| AU (3) | AU2012239888B9 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013025633A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2831480C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2694116T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2685824T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX357227B (cg-RX-API-DMAC7.html) |
| PL (1) | PL2694116T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2694116T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012139080A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012139080A2 (en) * | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| WO2013110013A1 (en) | 2012-01-20 | 2013-07-25 | Annapragada, Ananth | Methods and compositions for objectively characterizing medical images |
| US9512092B2 (en) | 2013-12-12 | 2016-12-06 | Albert Einstein College Of Medicine, Inc. | Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof |
| MX371295B (es) * | 2014-10-08 | 2020-01-24 | Texas Childrens Hospital | Formación de imágenes por irm de placas amiloides usando liposomas. |
| GB201509934D0 (en) | 2015-06-08 | 2015-07-22 | King S College London | Nanoparticles |
| ES2985317T3 (es) * | 2016-05-16 | 2024-11-05 | Univ Texas | Composiciones para la distribución de ARNt en nanopartículas y procedimientos de uso de las mismas |
| EP3548002B1 (en) * | 2016-11-30 | 2025-04-30 | Texas Children's Hospital | Hydrophilic fluorinated molecules for liposomal 19f mri probes with unique mr signatures |
| US20200261605A1 (en) * | 2019-01-24 | 2020-08-20 | Alzeca Biosciences, LLC | Functionalized liposomes for imaging misfolded proteins |
| KR102546470B1 (ko) * | 2020-01-29 | 2023-06-21 | 텍사스 칠드런스 하스피탈 | 아밀로이드 침착의 mri용 표적 조영제 |
| JP2023514991A (ja) * | 2020-02-12 | 2023-04-12 | テキサス チルドレンズ ホスピタル | α－シンヌクレイン沈着物のＭＲＩのための標的造影剤 |
| US11779664B2 (en) | 2020-02-12 | 2023-10-10 | Texas Children's Hospital | Targeted contrast agents for MRI of alpha-synuclein deposition |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331751A (en) * | 1980-11-17 | 1982-05-25 | Eastman Kodak Company | Electrically photosensitive materials and elements for photoelectrophoretic imaging processes |
| US5204085A (en) | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
| US5674468A (en) | 1992-03-06 | 1997-10-07 | Nycomed Imaging As | Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons |
| CA2185810A1 (en) | 1994-03-28 | 1995-10-05 | Jo Klaveness | Liposomes |
| US6071532A (en) | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
| ATE287700T1 (de) | 1999-11-30 | 2005-02-15 | Univ Arizona | Strahlung-sensitive liposomen |
| US7029655B2 (en) * | 2000-10-04 | 2006-04-18 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| US6821504B2 (en) * | 2001-05-23 | 2004-11-23 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| JP2005519129A (ja) | 2002-03-05 | 2005-06-30 | クリーブランド ステート ユニバーシティー | エアロゾル薬物送達のための凝集粒子 |
| US7605182B2 (en) | 2003-05-01 | 2009-10-20 | Aposense Ltd. | Compounds that selectively bind to membranes of apoptotic cells |
| US7208174B2 (en) * | 2003-12-18 | 2007-04-24 | Hoffmann-La Roche Inc. | Liposome compositions |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| US8357351B2 (en) | 2004-04-21 | 2013-01-22 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| US7713517B2 (en) * | 2004-04-21 | 2010-05-11 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| WO2006026184A2 (en) * | 2004-08-20 | 2006-03-09 | Washington University | Blood brain barrier permeation peptides |
| ATE493152T1 (de) * | 2004-09-23 | 2011-01-15 | Guerbet Sa | Liposomale kontrastmittel für die cest-bildgebung |
| EP1888034A2 (en) * | 2005-05-26 | 2008-02-20 | Yissum Research Development Company, of The Hebrew University of Jerusalem | Compositions and methods using same for delivering agents into a target organ protected by a blood barrier |
| US20070160658A1 (en) * | 2005-10-20 | 2007-07-12 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| EP2010223A2 (en) | 2006-04-07 | 2009-01-07 | The Board Of Trustees Of The University Of Illinois | Hydrophilic polymer-conjugated lipids for peptide and protein folding disorders |
| US20090123047A1 (en) | 2007-03-21 | 2009-05-14 | Yfantis Spyros A | Method and system for characterizing prostate images |
| EP1982733A1 (en) | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| WO2009015397A1 (en) | 2007-07-26 | 2009-01-29 | Nanoscan Imaging, Llc | Methods for imaging using improved nanoparticulate contrast agents |
| AU2008331764A1 (en) | 2007-12-05 | 2009-06-11 | Marval Biosciences, Inc. | Nano-scale contrast agents and methods of use |
| EP2242505A4 (en) | 2008-01-08 | 2012-03-07 | Biogenerix Ag | GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES |
| ITMI20081052A1 (it) * | 2008-06-10 | 2009-12-11 | Univ Milano Bicocca | Liposomi in grado di legare efficacemente il peptide beta-amiloide |
| WO2009152445A1 (en) | 2008-06-13 | 2009-12-17 | Marval Biosciences, Inc. | Imaging of atherosclerotic plaques using liposomal imaging agents |
| WO2010017094A2 (en) * | 2008-07-31 | 2010-02-11 | The General Hospital Corporation | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING |
| AR074760A1 (es) | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| JP2012520898A (ja) | 2009-03-19 | 2012-09-10 | マーヴァル バイオサイエンシーズ，インコーポレイテッド | 画像化におけるコントラスト強調のための組成物および方法 |
| US9334304B2 (en) * | 2009-04-02 | 2016-05-10 | The Johns Hopkins University | Self-assembling peptides bearing organic electronic functionality and applications employing the same |
| EP2501696B1 (en) | 2009-10-15 | 2016-12-28 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| ES2526124T3 (es) | 2010-06-16 | 2015-01-07 | Cymabay Therapeutics, Inc. | Agonistas del receptor GPR120 y sus usos |
| JP5998158B2 (ja) | 2011-03-02 | 2016-09-28 | センスリン，エルエルシー | ベシクル組成物 |
| WO2012139080A2 (en) | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| WO2013110013A1 (en) | 2012-01-20 | 2013-07-25 | Annapragada, Ananth | Methods and compositions for objectively characterizing medical images |
| WO2013164763A2 (en) | 2012-04-30 | 2013-11-07 | Innovative Health Diagnostics | A biological complex specific for alzheimer's disease detection in vitro and use thereof |
| AU2014240042C1 (en) | 2013-03-14 | 2019-09-05 | Celltaxis, Llc | Inhibitors of leukotriene A4 hydrolase |
| MX371295B (es) | 2014-10-08 | 2020-01-24 | Texas Childrens Hospital | Formación de imágenes por irm de placas amiloides usando liposomas. |
-
2012
- 2012-04-06 WO PCT/US2012/032649 patent/WO2012139080A2/en not_active Ceased
- 2012-04-06 AU AU2012239888A patent/AU2012239888B9/en not_active Ceased
- 2012-04-06 CN CN201280017548.6A patent/CN104144708B/zh not_active Expired - Fee Related
- 2012-04-06 DK DK12767275.6T patent/DK2694116T3/en active
- 2012-04-06 KR KR1020137029510A patent/KR101973063B1/ko not_active Expired - Fee Related
- 2012-04-06 CA CA2831480A patent/CA2831480C/en not_active Expired - Fee Related
- 2012-04-06 US US13/441,816 patent/US9801957B2/en not_active Expired - Fee Related
- 2012-04-06 EP EP12767275.6A patent/EP2694116B1/en not_active Not-in-force
- 2012-04-06 ES ES12767275.6T patent/ES2685824T3/es active Active
- 2012-04-06 EP EP18167725.3A patent/EP3366313A1/en not_active Withdrawn
- 2012-04-06 KR KR1020197007384A patent/KR102035187B1/ko not_active Expired - Fee Related
- 2012-04-06 PT PT12767275T patent/PT2694116T/pt unknown
- 2012-04-06 MX MX2013011231A patent/MX357227B/es active IP Right Grant
- 2012-04-06 PL PL12767275T patent/PL2694116T3/pl unknown
- 2012-04-06 BR BR112013025633A patent/BR112013025633A2/pt not_active Application Discontinuation
- 2012-04-06 JP JP2014504057A patent/JP6212032B2/ja not_active Expired - Fee Related
-
2017
- 2017-09-14 JP JP2017176383A patent/JP6533813B2/ja not_active Expired - Fee Related
- 2017-09-21 AU AU2017232156A patent/AU2017232156C1/en not_active Ceased
-
2019
- 2019-05-27 JP JP2019098174A patent/JP2019151664A/ja active Pending
- 2019-10-08 AU AU2019246775A patent/AU2019246775A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX357227B (es) | Nanoparticulas basadas en lipidos. | |
| WO2011130164A3 (en) | Unconjugated anti-tfr antibodies and compositions thereof for the treatment of cancer | |
| IL245889A0 (en) | Sulfonamide derivatives as bcl-2-selective apoptosis inducers for the treatment of cancer and immune diseases | |
| EP2707369A4 (en) | COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | |
| MX340055B (es) | Metodos y composiciones de nanoparticulas sin priones. | |
| MX359327B (es) | Composiciones y sus usos para tratar y prevenir la enfermedad de huntington. | |
| MY188911A (en) | Methods of treating bladder cancer | |
| MX2019000225A (es) | Composiciones y metodos para el tratamiento de enfermedades autoinmunes y otras enfermedades. | |
| WO2012006421A3 (en) | Diagnosis and treatment of breast cancer | |
| IL226377A0 (en) | Preparations of isoflavone nanoparticles and methods for their preparation and use | |
| SG11201403272YA (en) | Compositions and methods for treating alzheimer's disease | |
| IL220974A0 (en) | Compositions and methods for the diagnosis and treatment of tumor | |
| IL223819A0 (en) | 3-amino-5,6-dihydro-1h-pyrazin-2-one derivatives useful for the treatement of alzheimer's disease and other forms of dementia | |
| WO2010121164A3 (en) | 1,4-benzodiazepinone compounds and their use in treating cancer | |
| WO2011044537A9 (en) | Methods for treating alzheimer's disease | |
| PL2726470T3 (pl) | Pochodne 1,2,4-tiadiazol-5-ilo piperazyny przydatne w leczeniu chorób neurodegeneracyjnych | |
| EP4023243A3 (en) | Compositions and methods for treating celiac sprue disease | |
| WO2010105035A9 (en) | Prevention, treatment, and diagnosis of alzheimer's disease through electromagnetic field exposure | |
| WO2012040331A3 (en) | Multistage nanoparticles | |
| HK1215391A1 (zh) | 使用胎盘细胞外基质治疗口腔病变 | |
| ZA201209452B (en) | Gold complexes for use in the treatment of cancer | |
| PL2331092T3 (pl) | Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu | |
| WO2012153253A3 (en) | Aromatic compounds and metal complexes thereof | |
| IL217149A0 (en) | Compositions and methods for treating parkinson's disease | |
| WO2011041701A3 (en) | Inplantable contrast agents and methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |