AU2012239888B9 - Lipid-based nanoparticles - Google Patents

Lipid-based nanoparticles Download PDF

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Publication number
AU2012239888B9
AU2012239888B9 AU2012239888A AU2012239888A AU2012239888B9 AU 2012239888 B9 AU2012239888 B9 AU 2012239888B9 AU 2012239888 A AU2012239888 A AU 2012239888A AU 2012239888 A AU2012239888 A AU 2012239888A AU 2012239888 B9 AU2012239888 B9 AU 2012239888B9
Authority
AU
Australia
Prior art keywords
aromatic compound
phospholipid
liposomal composition
polymer
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012239888A
Other languages
English (en)
Other versions
AU2012239888A1 (en
AU2012239888B2 (en
AU2012239888A2 (en
Inventor
Ananth Annapragada
Stephen C. Cook
Indrani DASGUPTA
Jason L. Eriksen
Eric A. Tanifum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alzeca Biosciences LLC
University of Texas System
University of Houston System
Original Assignee
ALZECA BIOSCIENCES LLC
University of Texas System
University of Houston System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46966277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2012239888(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ALZECA BIOSCIENCES LLC, University of Texas System, University of Houston System, University of Texas at Austin filed Critical ALZECA BIOSCIENCES LLC
Publication of AU2012239888A1 publication Critical patent/AU2012239888A1/en
Publication of AU2012239888A2 publication Critical patent/AU2012239888A2/en
Assigned to BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, BOARD OF REGENTS OF THE UNIVERSITY OF HOUSTON SYSTEM, Alzeca Biosciences, LLC reassignment BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM Amend patent request/document other than specification (104) Assignors: Alzeca Biosciences, LLC, BOARD OF REGENTS OF THE UNIVERSITY OF HOUSTON SYSTEM, BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, TEXAS CHILDREN'S HOSPITAL
Application granted granted Critical
Publication of AU2012239888B2 publication Critical patent/AU2012239888B2/en
Priority to AU2017232156A priority Critical patent/AU2017232156C1/en
Publication of AU2012239888B9 publication Critical patent/AU2012239888B9/en
Priority to AU2019246775A priority patent/AU2019246775A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AU2012239888A 2011-04-06 2012-04-06 Lipid-based nanoparticles Ceased AU2012239888B9 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2017232156A AU2017232156C1 (en) 2011-04-06 2017-09-21 Lipid –based nanoparticles
AU2019246775A AU2019246775A1 (en) 2011-04-06 2019-10-08 Lipid –based nanoparticles

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161472605P 2011-04-06 2011-04-06
US61/472,605 2011-04-06
PCT/US2012/032649 WO2012139080A2 (en) 2011-04-06 2012-04-06 Lipid-based nanoparticles

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017232156A Division AU2017232156C1 (en) 2011-04-06 2017-09-21 Lipid –based nanoparticles

Publications (4)

Publication Number Publication Date
AU2012239888A1 AU2012239888A1 (en) 2013-11-07
AU2012239888A2 AU2012239888A2 (en) 2014-05-08
AU2012239888B2 AU2012239888B2 (en) 2017-06-22
AU2012239888B9 true AU2012239888B9 (en) 2017-10-12

Family

ID=46966277

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2012239888A Ceased AU2012239888B9 (en) 2011-04-06 2012-04-06 Lipid-based nanoparticles
AU2017232156A Ceased AU2017232156C1 (en) 2011-04-06 2017-09-21 Lipid –based nanoparticles
AU2019246775A Abandoned AU2019246775A1 (en) 2011-04-06 2019-10-08 Lipid –based nanoparticles

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2017232156A Ceased AU2017232156C1 (en) 2011-04-06 2017-09-21 Lipid –based nanoparticles
AU2019246775A Abandoned AU2019246775A1 (en) 2011-04-06 2019-10-08 Lipid –based nanoparticles

Country Status (14)

Country Link
US (1) US9801957B2 (cg-RX-API-DMAC7.html)
EP (2) EP2694116B1 (cg-RX-API-DMAC7.html)
JP (3) JP6212032B2 (cg-RX-API-DMAC7.html)
KR (2) KR101973063B1 (cg-RX-API-DMAC7.html)
CN (1) CN104144708B (cg-RX-API-DMAC7.html)
AU (3) AU2012239888B9 (cg-RX-API-DMAC7.html)
BR (1) BR112013025633A2 (cg-RX-API-DMAC7.html)
CA (1) CA2831480C (cg-RX-API-DMAC7.html)
DK (1) DK2694116T3 (cg-RX-API-DMAC7.html)
ES (1) ES2685824T3 (cg-RX-API-DMAC7.html)
MX (1) MX357227B (cg-RX-API-DMAC7.html)
PL (1) PL2694116T3 (cg-RX-API-DMAC7.html)
PT (1) PT2694116T (cg-RX-API-DMAC7.html)
WO (1) WO2012139080A2 (cg-RX-API-DMAC7.html)

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WO2012139080A2 (en) * 2011-04-06 2012-10-11 Board Of Regents Of The University Of Texas System Lipid-based nanoparticles
WO2013110013A1 (en) 2012-01-20 2013-07-25 Annapragada, Ananth Methods and compositions for objectively characterizing medical images
US9512092B2 (en) 2013-12-12 2016-12-06 Albert Einstein College Of Medicine, Inc. Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
MX371295B (es) * 2014-10-08 2020-01-24 Texas Childrens Hospital Formación de imágenes por irm de placas amiloides usando liposomas.
GB201509934D0 (en) 2015-06-08 2015-07-22 King S College London Nanoparticles
ES2985317T3 (es) * 2016-05-16 2024-11-05 Univ Texas Composiciones para la distribución de ARNt en nanopartículas y procedimientos de uso de las mismas
EP3548002B1 (en) * 2016-11-30 2025-04-30 Texas Children's Hospital Hydrophilic fluorinated molecules for liposomal 19f mri probes with unique mr signatures
US20200261605A1 (en) * 2019-01-24 2020-08-20 Alzeca Biosciences, LLC Functionalized liposomes for imaging misfolded proteins
KR102546470B1 (ko) * 2020-01-29 2023-06-21 텍사스 칠드런스 하스피탈 아밀로이드 침착의 mri용 표적 조영제
JP2023514991A (ja) * 2020-02-12 2023-04-12 テキサス チルドレンズ ホスピタル α－シンヌクレイン沈着物のＭＲＩのための標的造影剤
US11779664B2 (en) 2020-02-12 2023-10-10 Texas Children's Hospital Targeted contrast agents for MRI of alpha-synuclein deposition

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Also Published As

Publication number Publication date
CN104144708B (zh) 2017-07-28
JP6212032B2 (ja) 2017-10-18
US9801957B2 (en) 2017-10-31
DK2694116T3 (en) 2018-09-03
AU2012239888A1 (en) 2013-11-07
AU2017232156C1 (en) 2019-10-24
JP6533813B2 (ja) 2019-06-19
BR112013025633A2 (pt) 2017-08-08
EP2694116A2 (en) 2014-02-12
WO2012139080A2 (en) 2012-10-11
PL2694116T3 (pl) 2018-12-31
ES2685824T3 (es) 2018-10-11
CA2831480C (en) 2020-09-29
MX2013011231A (es) 2015-03-05
CN104144708A (zh) 2014-11-12
PT2694116T (pt) 2018-10-12
EP2694116A4 (en) 2015-06-03
KR102035187B1 (ko) 2019-11-08
EP2694116B1 (en) 2018-06-13
AU2017232156B2 (en) 2019-07-11
AU2017232156A1 (en) 2017-10-12
WO2012139080A3 (en) 2014-05-01
US20120258044A1 (en) 2012-10-11
JP2019151664A (ja) 2019-09-12
AU2012239888B2 (en) 2017-06-22
KR101973063B1 (ko) 2019-04-30
CA2831480A1 (en) 2012-10-11
AU2012239888A2 (en) 2014-05-08
JP2014523854A (ja) 2014-09-18
MX357227B (es) 2018-07-02
HK1203827A1 (en) 2015-11-06
KR20190031334A (ko) 2019-03-25
JP2018035167A (ja) 2018-03-08
EP3366313A1 (en) 2018-08-29
KR20140074868A (ko) 2014-06-18
AU2019246775A1 (en) 2019-10-31

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 18 OCT 2013

SREP Specification republished
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired