MX352697B - Proceso para la preparacion de amidas del acido pirazol carboxilico. - Google Patents

Proceso para la preparacion de amidas del acido pirazol carboxilico.

Info

Publication number
MX352697B
MX352697B MX2013007914A MX2013007914A MX352697B MX 352697 B MX352697 B MX 352697B MX 2013007914 A MX2013007914 A MX 2013007914A MX 2013007914 A MX2013007914 A MX 2013007914A MX 352697 B MX352697 B MX 352697B
Authority
MX
Mexico
Prior art keywords
formula
oxygen
compound
sulfur
preparation
Prior art date
Application number
MX2013007914A
Other languages
English (en)
Other versions
MX2013007914A (es
Inventor
Faber Dominik
Terinek Miroslav
Koenig Stefan
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2013007914A publication Critical patent/MX2013007914A/es
Publication of MX352697B publication Critical patent/MX352697B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/56—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/62—Oximes having oxygen atoms of oxyimino groups esterified
    • C07C251/64—Oximes having oxygen atoms of oxyimino groups esterified by carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/02—Monothiocarbonic acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/02—Monothiocarbonic acids; Derivatives thereof
    • C07C329/04—Esters of monothiocarbonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
    • C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La invención se relaciona con un proceso de preparación de ácido 3-difluorometil-1-metil-1H-pirazol-4- carboxílico (9-diclorometileno-1,2,3,4-tetrahidro-1,4-metano-naftaleno-5-il)- amida mediante la acilación del oxígeno de la oxima del compuesto de fórmula VIII (Ver Formula) en presencia de un solvente y de un agente de acilación de la fórmula XI R1-C(X)-C1 (XI); donde X es oxígeno o sulfuro; R1 es cloro si X es oxígeno o sulfuro; o R1 es C1-C6alcoxi, CH3-C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno; y a) si R1 es cloro y el compuesto de fórmula XI se agregó al compuesto de fórmula VIII; en el que se hace reaccionar el producto obtenido de la fórmula XIIa (Ver Formula) donde X es oxígeno o sulfuro, con el compuesto de fórmula IX (Ver Formula) b) si R1 es cloro y el compuesto de fórmula VIII se agregó al compuesto de fórmula XI; o R. es C1-C6alcoxi, CH3- C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno; en el que se hace reaccionar el producto obtenido de la fórmula XII (Ver Formula) donde X es oxígeno o sulfuro; R1 es cloro si X es oxígeno o sulfuro; o R1 es C1-C6alcoxi, CH3-C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno con el compuesto de fórmula IX (Ver Formula).
MX2013007914A 2011-01-25 2012-01-25 Proceso para la preparacion de amidas del acido pirazol carboxilico. MX352697B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11151965 2011-01-25
PCT/EP2012/051075 WO2012101139A1 (en) 2011-01-25 2012-01-25 Process for the preparation of pyrazole carboxylic acid amide

Publications (2)

Publication Number Publication Date
MX2013007914A MX2013007914A (es) 2013-08-29
MX352697B true MX352697B (es) 2017-12-05

Family

ID=45524566

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013007914A MX352697B (es) 2011-01-25 2012-01-25 Proceso para la preparacion de amidas del acido pirazol carboxilico.

Country Status (19)

Country Link
US (1) US8895757B2 (es)
EP (1) EP2668166B1 (es)
JP (2) JP6133788B2 (es)
KR (1) KR101851781B1 (es)
CN (1) CN103339113B (es)
AR (1) AR084915A1 (es)
AU (1) AU2012210547B2 (es)
BR (1) BR112013018533A2 (es)
CA (1) CA2824730C (es)
CO (1) CO6751253A2 (es)
ES (1) ES2540211T3 (es)
HR (1) HRP20150658T1 (es)
IL (1) IL227317A (es)
MX (1) MX352697B (es)
PL (1) PL2668166T3 (es)
PT (1) PT2668166E (es)
TW (1) TWI534126B (es)
UY (1) UY33879A (es)
WO (1) WO2012101139A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI534126B (zh) * 2011-01-25 2016-05-21 先正達合夥公司 用於製備吡唑羧酸醯胺之方法
TWI510472B (zh) * 2012-02-15 2015-12-01 Syngenta Participations Ag 立體選擇性製備吡唑羧醯胺之方法
EP3575030B1 (en) 2017-03-31 2024-01-03 NSK Ltd. Laser welding device, laser processing device, laser welding method, bearing manufacturing method, machine manufacturing method, vehicle manufacturing method, bearing, machine, and vehicle
WO2024017788A1 (en) 2022-07-22 2024-01-25 Syngenta Crop Protection Ag Solid form of a heterocyclic amide derivative

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58194853A (ja) * 1982-05-11 1983-11-12 Showa Denko Kk シクロヘキセン−アセチルオキシム誘導体
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
PT1940813E (pt) 2005-10-25 2011-01-20 Syngenta Participations Ag Derivados de amidas heterocíclicas úteis como microbicidas
CN102026982A (zh) * 2008-05-14 2011-04-20 先正达参股股份有限公司 制备酰胺的方法
WO2010072631A1 (en) * 2008-12-24 2010-07-01 Syngenta Limited Methods for the preparation of fungicides
DK2462108T3 (da) 2009-08-06 2013-07-08 Syngenta Participations Ag Fremgangsmåde til fremstilling af pyrazolcarboxylsyreamider
MX2012012004A (es) * 2010-04-20 2012-12-17 Syngenta Participations Ag Proceso para preparar amidas de acidos carboxilicos pirazolicos.
US8524915B2 (en) * 2010-04-20 2013-09-03 Syngenta Crop Protection Llc Process for the preparation of pyrazole carboxylic acid amides
CN102906072B (zh) * 2010-04-20 2014-07-02 先正达参股股份有限公司 吡唑羧酸酰胺的制备方法
TWI534126B (zh) * 2011-01-25 2016-05-21 先正達合夥公司 用於製備吡唑羧酸醯胺之方法

Also Published As

Publication number Publication date
UY33879A (es) 2012-08-31
TW201245114A (en) 2012-11-16
PT2668166E (pt) 2015-08-27
PL2668166T3 (pl) 2015-09-30
CN103339113A (zh) 2013-10-02
JP6133788B2 (ja) 2017-05-24
TWI534126B (zh) 2016-05-21
CN103339113B (zh) 2015-07-22
EP2668166A1 (en) 2013-12-04
AU2012210547A1 (en) 2013-08-01
JP2017071614A (ja) 2017-04-13
IL227317A0 (en) 2013-09-30
US8895757B2 (en) 2014-11-25
US20130310592A1 (en) 2013-11-21
KR20140019333A (ko) 2014-02-14
IL227317A (en) 2014-11-30
HRP20150658T1 (hr) 2015-07-31
CO6751253A2 (es) 2013-09-16
CA2824730A1 (en) 2012-08-02
WO2012101139A1 (en) 2012-08-02
AU2012210547B2 (en) 2016-04-14
ES2540211T3 (es) 2015-07-09
AR084915A1 (es) 2013-07-10
JP2014504596A (ja) 2014-02-24
BR112013018533A2 (pt) 2016-07-12
CA2824730C (en) 2018-10-23
JP6419131B2 (ja) 2018-11-07
KR101851781B1 (ko) 2018-04-24
MX2013007914A (es) 2013-08-29
EP2668166B1 (en) 2015-05-13

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