MX347620B - Derivados de sulfonilaminopirrolidinona, su preparacion y aplicacion terapeutica. - Google Patents

Derivados de sulfonilaminopirrolidinona, su preparacion y aplicacion terapeutica.

Info

Publication number
MX347620B
MX347620B MX2014007671A MX2014007671A MX347620B MX 347620 B MX347620 B MX 347620B MX 2014007671 A MX2014007671 A MX 2014007671A MX 2014007671 A MX2014007671 A MX 2014007671A MX 347620 B MX347620 B MX 347620B
Authority
MX
Mexico
Prior art keywords
sulphonylaminopyrrolidinone
preparation
derivatives
therapeutic application
factor
Prior art date
Application number
MX2014007671A
Other languages
English (en)
Other versions
MX2014007671A (es
Inventor
Lassalle Gilbert
Altenburger Jean-Michel
Kirsch Reinhard
Mallart Sergio
Philippo-Orts Marie-Claire
Alet Nathalie
Pascal Herault Jean-
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2014007671A publication Critical patent/MX2014007671A/es
Publication of MX347620B publication Critical patent/MX347620B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a nuevos compuestos de sulfonilaminopirrolidinona que tienen actividad antitrombótica que, en particular, inhibe el factor de coagulación IXa y/o el factor Xa, a procesos para su preparación y a su uso como fármacos.
MX2014007671A 2011-12-21 2012-12-19 Derivados de sulfonilaminopirrolidinona, su preparacion y aplicacion terapeutica. MX347620B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11306733.4A EP2606893A1 (en) 2011-12-21 2011-12-21 Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application
PCT/EP2012/076224 WO2013092756A1 (en) 2011-12-21 2012-12-19 Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application

Publications (2)

Publication Number Publication Date
MX2014007671A MX2014007671A (es) 2014-11-25
MX347620B true MX347620B (es) 2017-05-04

Family

ID=47428640

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007671A MX347620B (es) 2011-12-21 2012-12-19 Derivados de sulfonilaminopirrolidinona, su preparacion y aplicacion terapeutica.

Country Status (18)

Country Link
US (1) US9150544B2 (es)
EP (2) EP2606893A1 (es)
JP (1) JP6104936B2 (es)
KR (1) KR20140106703A (es)
CN (1) CN104136030B (es)
AR (1) AR089397A1 (es)
AU (1) AU2012357123B2 (es)
BR (1) BR112014014869A2 (es)
CA (1) CA2859575A1 (es)
ES (1) ES2559854T3 (es)
IL (1) IL233238A (es)
IN (1) IN2014CN04861A (es)
MX (1) MX347620B (es)
RU (1) RU2014129787A (es)
SG (1) SG11201403336QA (es)
TW (1) TWI568727B (es)
UY (1) UY34543A (es)
WO (1) WO2013092756A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
CN104557928B (zh) * 2015-02-14 2016-08-24 佛山市赛维斯医药科技有限公司 一种含二环酰胺结构凝血因子Xa抑制剂、其制备方法及其用途
JP2022506850A (ja) * 2018-11-08 2022-01-17 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド 化学化合物
EP4070658A1 (de) 2021-04-06 2022-10-12 BIORoxx GmbH Verwendung von blutgerinnungshemmenden verbindungen als rodentizide
CN113264819A (zh) * 2021-05-25 2021-08-17 都创(上海)医药开发有限公司 一种基于连续流反应技术快速合成3-溴-2-氟苯甲醛的方法
US20240101531A1 (en) 2022-06-08 2024-03-28 Xenon Pharmaceuticals Inc. Pyridinamine derivatives and their use as potassium channel modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121947A1 (de) * 1991-07-03 1993-01-07 Basf Ag 2-(3-(4-amidino-phenyl))-propionsaeurederivate, ihre herstellung und verwendung
JP4223560B2 (ja) * 1996-12-13 2009-02-12 アヴェンティス ファーマシューティカルズ インコーポレイテッド スルホン酸又はスルホニルアミノｎ−（ヘテロアラルキル）アザヘテロシクリルアミド化合物
US6602864B1 (en) * 1996-12-13 2003-08-05 Aventis Pharma Deutschland Gmbh Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds
US6281227B1 (en) * 1996-12-13 2001-08-28 Aventis Pharma Deutschland Gmbh Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
IL123986A (en) * 1997-04-24 2011-10-31 Organon Nv Medicinal compounds

Also Published As

Publication number Publication date
WO2013092756A1 (en) 2013-06-27
AU2012357123A1 (en) 2014-07-10
ES2559854T3 (es) 2016-02-16
CN104136030A (zh) 2014-11-05
RU2014129787A (ru) 2016-02-10
CA2859575A1 (en) 2013-06-27
US20140329801A1 (en) 2014-11-06
EP2606893A1 (en) 2013-06-26
US9150544B2 (en) 2015-10-06
CN104136030B (zh) 2017-03-01
MX2014007671A (es) 2014-11-25
IN2014CN04861A (es) 2015-09-18
TWI568727B (zh) 2017-02-01
TW201331195A (zh) 2013-08-01
IL233238A0 (en) 2014-08-31
BR112014014869A2 (pt) 2017-06-13
EP2793887B1 (en) 2015-10-21
JP6104936B2 (ja) 2017-03-29
SG11201403336QA (en) 2014-07-30
EP2793887A1 (en) 2014-10-29
AU2012357123B2 (en) 2016-12-15
AR089397A1 (es) 2014-08-20
KR20140106703A (ko) 2014-09-03
JP2015502382A (ja) 2015-01-22
UY34543A (es) 2013-06-28
IL233238A (en) 2016-10-31

Similar Documents

Publication Publication Date Title
JO3357B1 (ar) مركبات إيميدازوبيروليدينون
IN2012DN01269A (es)
CL2014002757A1 (es) Compuestos derivados de benzamida para inhibir la actividad de abl1, abl2 y bcr-abl1, composicion farmaceutica; y uso en el tratamiento del cancer.
GB201118656D0 (en) New compounds
PH12015500274B1 (en) Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
BR112015000704A2 (pt) imidazotriazinacarbonitrilas úteis como inibidores de quinase
MX349004B (es) Nuevos compuestos.
IN2014DN09434A (es)
PL2768937T3 (pl) Preparaty, ich zastosowanie jako środków do mycia naczyń lub do wytwarzania środków do mycia naczyń i ich wytwarzanie
MX344238B (es) Compuestos de tetrazol y métodos para preparar y usar los mismos.
MX343706B (es) Derivados heterocíclicos novedosos.
GB201209609D0 (en) New compounds
DK3045456T3 (da) Bicyklisk substituerede uraciler og anvendelse heraf
MX356728B (es) Combinación farmacéutica para usar en el tratamiento de pacientes que padecen diabetes de tipo 2.
MX347620B (es) Derivados de sulfonilaminopirrolidinona, su preparacion y aplicacion terapeutica.
UY30585A1 (es) Derivados de isoserina como inhibidores del factor ixa de la coagulacion
DK2175877T3 (da) Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme
TN2010000266A1 (en) Oxazolidinones for the treatment and/or prophylaxis of heart failure
WO2014029888A3 (en) Branched or macrocyclic polyamines and uses thereof
AU2012307449A8 (en) Sulfonic acid salts of heterocyclylamide-substituted imidazoles
MX2012012978A (es) Metodo para producir pleurodesis.
WO2013038200A3 (en) Neurodevelopmental disorders
PH12015500282A1 (en) N-acylhydrazone derivatives for selective t cell inhibitor and anti-lymphoid malignancy drug
MX2013009456A (es) Compuestos de azufre aromaticos sustituidos y metodos para su uso.
IN2014DN10683A (es)

Legal Events

Date Code Title Description
FG Grant or registration