UY30585A1 - Derivados de isoserina como inhibidores del factor ixa de la coagulacion - Google Patents

Derivados de isoserina como inhibidores del factor ixa de la coagulacion

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Publication number
UY30585A1
UY30585A1 UY30585A UY30585A UY30585A1 UY 30585 A1 UY30585 A1 UY 30585A1 UY 30585 A UY30585 A UY 30585A UY 30585 A UY30585 A UY 30585A UY 30585 A1 UY30585 A1 UY 30585A1
Authority
UY
Uruguay
Prior art keywords
inhibitors
coagulation
isoserine derivatives
ixa factor
isoserine
Prior art date
Application number
UY30585A
Other languages
English (en)
Inventor
Dr Herman Schreuder
Dr Markus Follmann
Dr Henning Steinhagen
Dr Jochen Goerlitzer
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY30585A1 publication Critical patent/UY30585A1/es

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    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
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    • A61P35/00—Antineoplastic agents
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
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Abstract

Derivados de isoserina como inhibidores del factor IXa de la coagulacion La invencion se refiere a compuestos de la formula I que tienen actividad antitrombotica, que en particular inhiben el factor IXa de la coagulacion sanguínea, a procesos para su preparacion y a la utilizacion de éstos como medicamentos.
UY30585A 2006-09-13 2007-09-11 Derivados de isoserina como inhibidores del factor ixa de la coagulacion UY30585A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102006042926 2006-09-13

Publications (1)

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UY30585A1 true UY30585A1 (es) 2008-05-02

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UY30585A UY30585A1 (es) 2006-09-13 2007-09-11 Derivados de isoserina como inhibidores del factor ixa de la coagulacion

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US (1) US8097758B2 (es)
EP (1) EP2069289B1 (es)
JP (1) JP5249226B2 (es)
KR (1) KR20090050081A (es)
CN (1) CN101516834B (es)
AR (1) AR063708A1 (es)
AU (1) AU2007297013B2 (es)
BR (1) BRPI0716991A2 (es)
CA (1) CA2663544A1 (es)
CL (1) CL2007002652A1 (es)
IL (1) IL197504A (es)
MA (1) MA30707B1 (es)
MX (1) MX2009002047A (es)
MY (1) MY150745A (es)
NO (1) NO20091110L (es)
NZ (1) NZ575603A (es)
RU (1) RU2446157C2 (es)
SG (1) SG174080A1 (es)
TW (1) TWI394570B (es)
UY (1) UY30585A1 (es)
WO (1) WO2008031509A1 (es)
ZA (1) ZA200900807B (es)

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US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US8221804B2 (en) 2005-02-03 2012-07-17 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
CA2662626C (en) * 2006-09-07 2016-07-26 Industrial Research Limited Acyclic amine inhibitors of 5'-methylthioadenosine phosphorylase and nucleosidase
EP2282735B1 (en) 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes
AU2009322342A1 (en) 2008-12-05 2011-06-30 Merck Sharp & Dohme Corp. Morpholinone compounds as factor IXa inhibitors
EP2473491B1 (en) * 2009-08-31 2013-07-17 Mochida Pharmaceutical Co., Ltd. Morpholinone compounds as factor ixa inhibitors
US9969724B2 (en) 2014-04-16 2018-05-15 Merck Sharp & Dohme Corp. Factor IXa inhibitors
CN109627218B (zh) * 2018-11-27 2022-03-29 深圳市龙华区中心医院 一种抗凝小分子化合物及其应用和包含其的药物

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CN101516834B (zh) 2013-04-03
KR20090050081A (ko) 2009-05-19
MX2009002047A (es) 2009-03-06
US8097758B2 (en) 2012-01-17
MA30707B1 (fr) 2009-09-01
NZ575603A (en) 2011-03-31
EP2069289A1 (de) 2009-06-17
IL197504A0 (en) 2009-12-24
BRPI0716991A2 (pt) 2013-10-08
EP2069289B1 (de) 2013-10-02
TW200829245A (en) 2008-07-16
AU2007297013B2 (en) 2012-05-31
RU2009113602A (ru) 2010-10-20
NO20091110L (no) 2009-06-09
MY150745A (en) 2014-02-28
AR063708A1 (es) 2009-02-11
CN101516834A (zh) 2009-08-26
CA2663544A1 (en) 2008-03-20
SG174080A1 (en) 2011-09-29
RU2446157C2 (ru) 2012-03-27
JP5249226B2 (ja) 2013-07-31
ZA200900807B (en) 2009-11-25
US20090233949A1 (en) 2009-09-17
AU2007297013A1 (en) 2008-03-20
IL197504A (en) 2013-06-27
TWI394570B (zh) 2013-05-01
JP2010503625A (ja) 2010-02-04
CL2007002652A1 (es) 2008-02-08

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