MX345730B - Células adherentes derivadas del amnios (amdac) para usarse en el tratamiento de enfermedades y trastornos relacionados con el sistema inmunitario. - Google Patents

Células adherentes derivadas del amnios (amdac) para usarse en el tratamiento de enfermedades y trastornos relacionados con el sistema inmunitario.

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Publication number
MX345730B
MX345730B MX2013006791A MX2013006791A MX345730B MX 345730 B MX345730 B MX 345730B MX 2013006791 A MX2013006791 A MX 2013006791A MX 2013006791 A MX2013006791 A MX 2013006791A MX 345730 B MX345730 B MX 345730B
Authority
MX
Mexico
Prior art keywords
immune
adherent cells
disorders
treatment
derived adherent
Prior art date
Application number
MX2013006791A
Other languages
English (en)
Other versions
MX2013006791A (es
Inventor
W Edinger James
Abbot Stewart
Jankovic Vladimir
Liang Bitao
Francki Aleksandar
Original Assignee
Anthrogenesis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthrogenesis Corp filed Critical Anthrogenesis Corp
Publication of MX2013006791A publication Critical patent/MX2013006791A/es
Publication of MX345730B publication Critical patent/MX345730B/es

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    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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Abstract

La presente invención se refiere a células adherentes derivadas del amnios (AMDC), y poblaciones de, y composiciones que contienen, tales células, para usarse en la modulación de una respuesta inmune. En algunas modalidades la respuesta inmune es la enfermedad de injerto contra hospedero, una alergia, asma o una enfermedad o trastorno relacionado con el sistema inmunitario, por ejemplo, una enfermedad autoinmune.
MX2013006791A 2010-12-17 2011-12-15 Células adherentes derivadas del amnios (amdac) para usarse en el tratamiento de enfermedades y trastornos relacionados con el sistema inmunitario. MX345730B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061424593P 2010-12-17 2010-12-17
PCT/US2011/065158 WO2012083021A1 (en) 2010-12-17 2011-12-15 Treatment of immune-related diseases and disorders using amnion derived adherent cells

Publications (2)

Publication Number Publication Date
MX2013006791A MX2013006791A (es) 2013-09-06
MX345730B true MX345730B (es) 2017-02-14

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MX2013006791A MX345730B (es) 2010-12-17 2011-12-15 Células adherentes derivadas del amnios (amdac) para usarse en el tratamiento de enfermedades y trastornos relacionados con el sistema inmunitario.

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US (1) US20120164114A1 (es)
EP (1) EP2652126B1 (es)
JP (1) JP2014501249A (es)
KR (7) KR20190114045A (es)
CN (1) CN103403150A (es)
AU (1) AU2011343736A1 (es)
CA (1) CA2821809C (es)
ES (1) ES2599331T3 (es)
MX (1) MX345730B (es)
NZ (1) NZ611981A (es)
WO (1) WO2012083021A1 (es)

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Publication number Priority date Publication date Assignee Title
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
CA2841713A1 (en) * 2011-07-15 2013-01-24 Anthrogenesis Corporation Treatment of radiation injury using amnion derived adherent cells
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
US8768049B2 (en) * 2012-07-13 2014-07-01 Seiko Epson Corporation Small vein image recognition and authorization using constrained geometrical matching and weighted voting under generic tree model
US9950014B2 (en) * 2012-09-04 2018-04-24 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
CN103655614B (zh) * 2012-09-19 2019-06-28 西比曼生物科技(上海)有限公司 脂肪组织祖细胞在预防或治疗肝炎中的应用
WO2014063035A2 (en) * 2012-10-19 2014-04-24 Anthrogenesis Corporation Treatment of pain using amnion derived adherent cells
AU2014215458A1 (en) * 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US20160008401A1 (en) * 2013-03-01 2016-01-14 Apceth Gmbh & Co. Kg Protection of the vascular endothelium from immunologically mediated cytotoxic reactions with human cd34-negative progenitor cells
EP2968646B1 (en) 2013-03-13 2019-05-29 AlloSource Fascia fibrous compositions and methods for their use and manufacture
KR102312720B1 (ko) 2013-03-15 2021-10-13 알로소스 연조직 회복 및 재생을 위한 세포 재배치된 콜라겐 매트릭스
US10485521B2 (en) * 2013-05-10 2019-11-26 MAM Holdings of West Florida, L.L.C. Method for obtaining sterile human amniotic fluid and uses thereof
JP2016523102A (ja) * 2013-06-24 2016-08-08 アントフロゲネシス コーポレーション T細胞を増殖させるための方法
JP6173157B2 (ja) * 2013-10-02 2017-08-02 日本製薬株式会社 Il−17産生抑制組成物
CN113679740A (zh) * 2013-11-15 2021-11-23 人类起源公司 包含人胎盘灌注液细胞、其亚群的组合物及其用途
AU2014360195B2 (en) 2013-12-06 2018-02-08 Allosource Method of drying sheets of tissue
WO2015120077A1 (en) * 2014-02-04 2015-08-13 Gonzalez Jose Javier Lopez Biologically optimized adult mesenchymal stem cells
CN106139163B (zh) * 2015-04-27 2019-11-19 崔磊 一种抑制骨关节炎的microRNA及其应用
MX2017015147A (es) * 2015-05-26 2018-03-28 Celularity Inc Angiogenesis usando celulas madre de placenta estimuladas.
TWI589698B (zh) * 2015-07-22 2017-07-01 中國醫藥大學 間質幹細胞、其純株化擴張之方法、其分離方法及其應用
CN106153919B (zh) * 2016-06-16 2018-06-29 汕头大学医学院 CD105,esVEGR2和MYC三蛋白联合预测食管鳞癌患者预后试剂盒
WO2018002930A1 (en) 2016-06-30 2018-01-04 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
CN109952371A (zh) 2016-11-15 2019-06-28 株式会社钟化 包含来自胎儿附属物的间充质系干细胞的细胞群、其制备方法、以及医药组合物
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
US10987381B2 (en) * 2017-01-27 2021-04-27 Neil Riordan Mesenchymal stem cells with enhanced efficacy in treatment of autoimmunity particularly rheumatoid arthritis
WO2018211486A1 (en) * 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
CN111093680A (zh) * 2017-09-15 2020-05-01 洋蓟治疗有限公司 治疗变应性气道疾病(aad)/哮喘的方法
EP3710060A4 (en) 2017-11-16 2021-05-19 Aivita Biomedical, Inc. USE OF CELL MEMBRANE-RELATED SIGNALING FACTORS
WO2019132026A1 (ja) 2017-12-28 2019-07-04 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
CN110090227B (zh) * 2018-04-18 2021-03-26 浙江大学 人羊膜上皮细胞在治疗移植物抗宿主病中的用途
CN114470001A (zh) * 2018-04-18 2022-05-13 浙江大学 人羊膜上皮细胞在自身免疫性疾病中的治疗用途
KR102091748B1 (ko) * 2018-05-04 2020-03-20 차의과학대학교 산학협력단 수지상세포의 이동능을 증가시키는 방법 및 이의 용도
CN108904799A (zh) * 2018-07-09 2018-11-30 夏荣木 一种抗肿瘤制剂及制备的方法
CN109528751B (zh) * 2018-10-29 2021-03-09 哈尔滨医科大学 miR-296及其模拟物在促进骨髓间充质干细胞成骨分化及骨形成中的应用
CN114585373B (zh) 2019-05-06 2025-07-22 艾克塞利瑞提德生物技术公司 前体调节性细胞滋养层细胞及其用途
WO2020251020A1 (ja) 2019-06-14 2020-12-17 株式会社カネカ 間葉系細胞を含む細胞集団、それを含む医薬組成物、及び、その製造方法
CN113358528B (zh) * 2021-06-08 2022-06-17 山东大学 一种基于悬滴法检测乙酰胆碱酯酶及其抑制剂的方法
EP4389124A4 (en) * 2021-08-19 2025-06-11 Kangstem Biotech Co., Ltd. Method for treating immune diseases by using calcineurin inhibitor and stem cells
CN114288386B (zh) * 2022-01-25 2023-12-12 华中科技大学同济医学院附属协和医院 Del-1作为炎症性肠病新的生物标志物及治疗药物应用
CN114717185A (zh) * 2022-03-31 2022-07-08 秦岭大熊猫研究中心(陕西省珍稀野生动物救护基地) 一种大熊猫胎盘间充质干细胞分离与培养方法
CN116077530B (zh) * 2022-11-21 2024-08-09 中南大学 预处理的人羊膜上皮细胞在制备治疗和/或预防炎症疾病药物中的应用
CN116144598B (zh) * 2023-04-06 2023-09-01 中科中銮生物科技(广东)有限公司 一种促进神经干细胞增殖和分化的培养基及其应用
EP4704868A1 (en) * 2023-05-04 2026-03-11 Hudson Institute of Medical Research Method of treatment
CN118105409B (zh) * 2024-01-30 2025-11-25 浙江大学 水凝胶包被的人羊膜上皮干细胞及其外泌体在制备改善肠炎药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101569168B1 (ko) * 2007-02-12 2015-11-13 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
EP2217250A4 (en) * 2007-11-09 2011-01-05 California Inst Of Techn IMMUNOMODULATING COMPOUNDS AND RELEVANT COMPOSITIONS AND METHODS
CN102282252B (zh) * 2008-11-19 2017-07-04 人类起源公司 羊膜来源的贴壁细胞
ES2553712T3 (es) * 2009-11-30 2015-12-11 Pluristem Ltd. Células adherentes de la placenta y uso de las mismas en el tratamiento de enfermedad

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