MX342930B - Composicion reticuladora mejorada, suministrada por iontoforesis, util para el tratamiento de queratocono. - Google Patents
Composicion reticuladora mejorada, suministrada por iontoforesis, util para el tratamiento de queratocono.Info
- Publication number
- MX342930B MX342930B MX2014004297A MX2014004297A MX342930B MX 342930 B MX342930 B MX 342930B MX 2014004297 A MX2014004297 A MX 2014004297A MX 2014004297 A MX2014004297 A MX 2014004297A MX 342930 B MX342930 B MX 342930B
- Authority
- MX
- Mexico
- Prior art keywords
- keratoconus
- iontophoresis
- treatment
- useful
- linking composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a una formulación mejorada de una composición oftálmica que contiene riboflavina, como agente reticulador del colágeno de la córnea, administrada mediante iontoforesis en la córnea, capaz de garantizar una capacidad incrementada de permeación de la riboflavina en el estroma de la córnea y, por lo tanto, mayor eficacia terapéutica en el tratamiento de queratocono.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000560A ITRM20110560A1 (it) | 2011-10-25 | 2011-10-25 | Migliorata composizione di cross-linking per il trattamento del cheratocono mediante iontoforesi |
PCT/IT2012/000324 WO2013061350A1 (en) | 2011-10-25 | 2012-10-24 | Improved cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014004297A MX2014004297A (es) | 2014-07-24 |
MX342930B true MX342930B (es) | 2016-10-19 |
Family
ID=45315962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014004297A MX342930B (es) | 2011-10-25 | 2012-10-24 | Composicion reticuladora mejorada, suministrada por iontoforesis, util para el tratamiento de queratocono. |
Country Status (16)
Country | Link |
---|---|
US (1) | US9439908B2 (es) |
EP (1) | EP2770979B1 (es) |
JP (1) | JP5913606B2 (es) |
KR (1) | KR101837238B1 (es) |
AU (1) | AU2012327916B2 (es) |
BR (1) | BR112014009761B8 (es) |
CA (1) | CA2851331C (es) |
EA (1) | EA026703B1 (es) |
ES (1) | ES2546263T3 (es) |
IL (1) | IL232194A (es) |
IN (1) | IN2014CN02972A (es) |
IT (1) | ITRM20110560A1 (es) |
MX (1) | MX342930B (es) |
PT (1) | PT2770979E (es) |
RS (1) | RS54139B1 (es) |
WO (1) | WO2013061350A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9622911B2 (en) | 2010-09-30 | 2017-04-18 | Cxl Ophthalmics, Llc | Ophthalmic treatment device, system, and method of use |
JP2014503552A (ja) | 2011-01-12 | 2014-02-13 | ソーフト イタリア エスピーエー | 円錐角膜の処置のためのイオン導入による架橋剤の角膜送達および関連眼科組成物 |
US9566301B2 (en) | 2012-03-29 | 2017-02-14 | Cxl Ophthalmics, Llc | Compositions and methods for treating or preventing diseases associated with oxidative stress |
EP2830627B1 (en) | 2012-03-29 | 2024-05-01 | Epion Therapeutics, Inc. | Ocular treatment solutions, delivery devices and delivery augmentation methods |
US9931199B2 (en) * | 2014-05-05 | 2018-04-03 | Roberto Gustavo ALBERTAZZI | Methods and apparatus for treating keratoconus |
US11207410B2 (en) | 2015-07-21 | 2021-12-28 | Avedro, Inc. | Systems and methods for treatments of an eye with a photosensitizer |
WO2017180851A1 (en) | 2016-04-13 | 2017-10-19 | Avedro, Inc. | Systems and methods for delivering drugs to an eye |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030023228A1 (en) * | 2001-07-20 | 2003-01-30 | Parkinson Thomas M. | Ocular iontophoretic device and method for using the same |
ITRM20070356A1 (it) * | 2007-06-26 | 2008-12-27 | Sooft Italia Srl | Soluzione oculare sterile monouso e suo procedimento di produzione per il cross linking corneale del cheratocono |
IT1393402B1 (it) * | 2008-08-28 | 2012-04-20 | Sooft Italia Spa | Uso di enhancer eventualmente con riboflavina, nonche' relative composizioni oftalmiche per cross-linking corneale del cheratocono o di altre patologie ectasiche corneali |
EP2289937A1 (en) | 2009-08-24 | 2011-03-02 | Wilfried Stücker | Production of monoclonal antibodies in vitro |
US20110288466A1 (en) * | 2010-04-13 | 2011-11-24 | Avedro, Inc. | Systems and methods for activating cross-linking in an eye |
-
2011
- 2011-10-25 IT IT000560A patent/ITRM20110560A1/it unknown
-
2012
- 2012-10-24 CA CA2851331A patent/CA2851331C/en active Active
- 2012-10-24 AU AU2012327916A patent/AU2012327916B2/en active Active
- 2012-10-24 US US14/353,872 patent/US9439908B2/en active Active
- 2012-10-24 RS RS20150504A patent/RS54139B1/en unknown
- 2012-10-24 JP JP2014537816A patent/JP5913606B2/ja not_active Expired - Fee Related
- 2012-10-24 KR KR1020147013678A patent/KR101837238B1/ko active IP Right Grant
- 2012-10-24 WO PCT/IT2012/000324 patent/WO2013061350A1/en active Application Filing
- 2012-10-24 PT PT128135340T patent/PT2770979E/pt unknown
- 2012-10-24 EP EP12813534.0A patent/EP2770979B1/en active Active
- 2012-10-24 BR BR112014009761A patent/BR112014009761B8/pt active IP Right Grant
- 2012-10-24 EA EA201490845A patent/EA026703B1/ru not_active IP Right Cessation
- 2012-10-24 ES ES12813534.0T patent/ES2546263T3/es active Active
- 2012-10-24 MX MX2014004297A patent/MX342930B/es active IP Right Grant
- 2012-10-24 IN IN2972CHN2014 patent/IN2014CN02972A/en unknown
-
2014
- 2014-04-22 IL IL232194A patent/IL232194A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR20140080553A (ko) | 2014-06-30 |
RS54139B1 (en) | 2015-12-31 |
WO2013061350A1 (en) | 2013-05-02 |
BR112014009761B1 (pt) | 2022-05-24 |
IN2014CN02972A (es) | 2015-07-03 |
AU2012327916B2 (en) | 2016-04-21 |
IL232194A (en) | 2016-09-29 |
CA2851331C (en) | 2019-11-12 |
MX2014004297A (es) | 2014-07-24 |
US20140303173A1 (en) | 2014-10-09 |
BR112014009761A2 (pt) | 2017-04-25 |
CN104023706A (zh) | 2014-09-03 |
ES2546263T3 (es) | 2015-09-22 |
EP2770979A1 (en) | 2014-09-03 |
JP2014530904A (ja) | 2014-11-20 |
CA2851331A1 (en) | 2013-05-02 |
US9439908B2 (en) | 2016-09-13 |
EP2770979B1 (en) | 2015-07-08 |
ITRM20110560A1 (it) | 2013-04-26 |
EA026703B1 (ru) | 2017-05-31 |
IL232194A0 (en) | 2014-06-30 |
JP5913606B2 (ja) | 2016-04-27 |
AU2012327916A1 (en) | 2014-05-22 |
BR112014009761B8 (pt) | 2022-09-06 |
KR101837238B1 (ko) | 2018-03-09 |
EA201490845A1 (ru) | 2014-07-30 |
PT2770979E (pt) | 2015-10-07 |
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Legal Events
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FG | Grant or registration |