MX340985B - Compuestos de n-heteroarilo. - Google Patents
Compuestos de n-heteroarilo.Info
- Publication number
- MX340985B MX340985B MX2013003635A MX2013003635A MX340985B MX 340985 B MX340985 B MX 340985B MX 2013003635 A MX2013003635 A MX 2013003635A MX 2013003635 A MX2013003635 A MX 2013003635A MX 340985 B MX340985 B MX 340985B
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- relates
- medicaments
- heteroaryl compounds
- treatments
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- 238000011282 treatment Methods 0.000 abstract 4
- 208000006968 Helminthiasis Diseases 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 208000014837 parasitic helminthiasis infectious disease Diseases 0.000 abstract 2
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10181553 | 2010-09-29 | ||
| US38846610P | 2010-09-30 | 2010-09-30 | |
| PCT/EP2011/066806 WO2012041873A1 (en) | 2010-09-29 | 2011-09-28 | N-heteroaryl compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013003635A MX2013003635A (es) | 2013-05-22 |
| MX340985B true MX340985B (es) | 2016-08-01 |
Family
ID=44719930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013003635A MX340985B (es) | 2010-09-29 | 2011-09-28 | Compuestos de n-heteroarilo. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8877934B2 (enExample) |
| EP (1) | EP2621903B1 (enExample) |
| JP (1) | JP5791725B2 (enExample) |
| KR (1) | KR101916481B1 (enExample) |
| CN (2) | CN103189356B (enExample) |
| AR (1) | AR083200A1 (enExample) |
| AU (1) | AU2011310592B2 (enExample) |
| BR (1) | BR112013006030B1 (enExample) |
| CA (1) | CA2811369C (enExample) |
| CO (1) | CO6710926A2 (enExample) |
| ES (1) | ES2622881T3 (enExample) |
| HU (1) | HUE034042T2 (enExample) |
| MX (1) | MX340985B (enExample) |
| NZ (1) | NZ607580A (enExample) |
| PL (1) | PL2621903T3 (enExample) |
| RU (1) | RU2596185C2 (enExample) |
| WO (1) | WO2012041873A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842144B2 (en) | 2011-05-13 | 2020-11-24 | The Climate Corporation | Method and system to map biological pests in agricultural fields using remotely-sensed data for field scouting and targeted chemical application |
| US10096073B2 (en) | 2011-05-13 | 2018-10-09 | The Climate Corporation | Systems to prescribe and deliver fertilizer over agricultural fields and related methods |
| EP2831042B1 (en) * | 2012-03-28 | 2019-07-31 | Intervet International B.V. | Heteroaryl compounds with a-cyclic bridging unit |
| NZ708680A (en) * | 2012-12-13 | 2018-05-25 | Dow Agrosciences Llc | Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates |
| RU2658825C2 (ru) * | 2012-12-13 | 2018-06-25 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы получения 4-амино-3-галоген-6(замещенных)пиколинатов и 4-амино-5-фтор-3-галоген-6-(замещенных)пиколинатов |
| EP3145904A1 (en) | 2014-05-21 | 2017-03-29 | Intervet International B.V. | Improved process for preparing substituted crotonic acids |
| MY195016A (en) | 2014-08-04 | 2023-01-03 | Nuevolution As | Optionally Fused Heterocyclyl-Substituted Derivatives of Pyrimidine Useful for The Treatment of Inflammatory, Metabolic, Oncologic and Autoimmune Diseases |
| AU2016378477A1 (en) * | 2015-12-23 | 2018-06-14 | Intervet International B.V. | Improved process for making crotonylaminopyridines |
| AR111260A1 (es) | 2017-03-31 | 2019-06-19 | Intervet Int Bv | Formulación farmacéutica de la sal de crotonil amino piridina |
| EP3898589A2 (de) | 2018-12-21 | 2021-10-27 | Saltigo GmbH | Verfahren zur herstellung von 2-alkoxy-4-amino-5-methyl-pyridinen und/oder von 2-alkoxy-4-alkylamino-5-methyl-pyridinen |
| JP7644121B2 (ja) | 2019-12-18 | 2025-03-11 | インターベット インターナショナル ベー． フェー． | アザインドール構造を含む駆虫剤化合物 |
| US11447479B2 (en) | 2019-12-20 | 2022-09-20 | Nuevolution A/S | Compounds active towards nuclear receptors |
| TWI872177B (zh) | 2019-12-20 | 2025-02-11 | 丹麥商紐韋盧森公司 | 對核受體具有活性之化合物 |
| CN110960485B (zh) * | 2020-01-06 | 2021-02-02 | 安丘市人民医院 | 一种用于治疗角膜炎的药物及其制备方法 |
| US11613532B2 (en) | 2020-03-31 | 2023-03-28 | Nuevolution A/S | Compounds active towards nuclear receptors |
| MX2022012260A (es) | 2020-03-31 | 2022-11-30 | Nuevolution As | Compuestos activos frente a receptores nucleares. |
| WO2025152919A1 (en) * | 2024-01-15 | 2025-07-24 | Impact Therapeutics (Shanghai) , Inc. | Crystal forms of a weel inhibitor and preparation method thereof |
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| WO2009051956A2 (en) | 2007-10-16 | 2009-04-23 | E. I. Du Pont De Nemours And Company | Pyrazole-substituted isoxazoline insecticides |
| CN101284812A (zh) * | 2008-06-05 | 2008-10-15 | 中山大学 | 他克林-阿魏酸杂联体,其制备方法及其药物组合物 |
| WO2010053517A2 (en) | 2008-10-29 | 2010-05-14 | Aroian Raffi V | Combination therapy to combat helminth resistance |
| US8007761B2 (en) | 2008-12-24 | 2011-08-30 | Praxair Technology, Inc. | Carbon dioxide emission reduction method |
-
2011
- 2011-09-28 CN CN201180052605.XA patent/CN103189356B/zh not_active Expired - Fee Related
- 2011-09-28 AR ARP110103573A patent/AR083200A1/es not_active Application Discontinuation
- 2011-09-28 CA CA2811369A patent/CA2811369C/en not_active Expired - Fee Related
- 2011-09-28 MX MX2013003635A patent/MX340985B/es active IP Right Grant
- 2011-09-28 BR BR112013006030-1A patent/BR112013006030B1/pt not_active IP Right Cessation
- 2011-09-28 KR KR1020137007888A patent/KR101916481B1/ko not_active Expired - Fee Related
- 2011-09-28 NZ NZ607580A patent/NZ607580A/en not_active IP Right Cessation
- 2011-09-28 RU RU2013119681/04A patent/RU2596185C2/ru active
- 2011-09-28 HU HUE11761595A patent/HUE034042T2/en unknown
- 2011-09-28 WO PCT/EP2011/066806 patent/WO2012041873A1/en not_active Ceased
- 2011-09-28 JP JP2013530709A patent/JP5791725B2/ja not_active Expired - Fee Related
- 2011-09-28 CN CN201510648665.8A patent/CN105294549B/zh not_active Expired - Fee Related
- 2011-09-28 PL PL11761595T patent/PL2621903T3/pl unknown
- 2011-09-28 AU AU2011310592A patent/AU2011310592B2/en not_active Ceased
- 2011-09-28 EP EP11761595.5A patent/EP2621903B1/en active Active
- 2011-09-28 US US13/876,724 patent/US8877934B2/en active Active
- 2011-09-28 ES ES11761595.5T patent/ES2622881T3/es active Active
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2013
- 2013-04-17 CO CO13099093A patent/CO6710926A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011310592B2 (en) | 2015-01-22 |
| CN103189356B (zh) | 2015-11-25 |
| KR101916481B1 (ko) | 2018-11-07 |
| PL2621903T3 (pl) | 2017-08-31 |
| BR112013006030A2 (pt) | 2016-06-07 |
| AR083200A1 (es) | 2013-02-06 |
| HUE034042T2 (en) | 2018-01-29 |
| BR112013006030B1 (pt) | 2020-03-17 |
| CA2811369C (en) | 2019-09-03 |
| EP2621903A1 (en) | 2013-08-07 |
| CN105294549A (zh) | 2016-02-03 |
| KR20130139889A (ko) | 2013-12-23 |
| WO2012041873A1 (en) | 2012-04-05 |
| US8877934B2 (en) | 2014-11-04 |
| ES2622881T3 (es) | 2017-07-07 |
| JP5791725B2 (ja) | 2015-10-07 |
| US20130196993A1 (en) | 2013-08-01 |
| CN103189356A (zh) | 2013-07-03 |
| NZ607580A (en) | 2015-01-30 |
| JP2014500235A (ja) | 2014-01-09 |
| CN105294549B (zh) | 2017-12-26 |
| RU2013119681A (ru) | 2014-11-10 |
| AU2011310592A1 (en) | 2013-03-14 |
| RU2596185C2 (ru) | 2016-08-27 |
| CA2811369A1 (en) | 2012-04-05 |
| CO6710926A2 (es) | 2013-07-15 |
| EP2621903B1 (en) | 2017-03-01 |
| MX2013003635A (es) | 2013-05-22 |
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