EA201591192A1 - Антибактериальные соединения - Google Patents

Антибактериальные соединения

Info

Publication number
EA201591192A1
EA201591192A1 EA201591192A EA201591192A EA201591192A1 EA 201591192 A1 EA201591192 A1 EA 201591192A1 EA 201591192 A EA201591192 A EA 201591192A EA 201591192 A EA201591192 A EA 201591192A EA 201591192 A1 EA201591192 A1 EA 201591192A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibacterial
connections
compounds
relates
present
Prior art date
Application number
EA201591192A
Other languages
English (en)
Other versions
EA038333B1 (ru
Inventor
Жером Эмиль Жорж Гийемон
Магали Мадлен Симон Мотт
Анил Коул
Насер Луни
Original Assignee
Янссен Сайенсиз Айрлэнд Юси
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47519922&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201591192(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Янссен Сайенсиз Айрлэнд Юси filed Critical Янссен Сайенсиз Айрлэнд Юси
Publication of EA201591192A1 publication Critical patent/EA201591192A1/ru
Publication of EA038333B1 publication Critical patent/EA038333B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles

Abstract

Настоящее изобретение относится к следующим соединениям для применения в лечении бактериальной инфекциигде целые числа определены в описании. Настоящее изобретение также относится к соединениям для применения в качестве лекарственных препаратов, фармацевтическим композициям и некоторым новым соединениям.
EA201591192A 2012-12-21 2013-12-20 Антибактериальные соединения EA038333B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12199026 2012-12-21
PCT/EP2013/077565 WO2014096300A2 (en) 2012-12-21 2013-12-20 Antibacterial compounds

Publications (2)

Publication Number Publication Date
EA201591192A1 true EA201591192A1 (ru) 2015-11-30
EA038333B1 EA038333B1 (ru) 2021-08-11

Family

ID=47519922

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201591192A EA038333B1 (ru) 2012-12-21 2013-12-20 Антибактериальные соединения

Country Status (22)

Country Link
US (3) US9428474B2 (ru)
EP (1) EP2934498B1 (ru)
JP (1) JP6441229B2 (ru)
KR (1) KR102233199B1 (ru)
CN (1) CN104981238B (ru)
AP (1) AP2015008503A0 (ru)
AU (1) AU2013366572B2 (ru)
BR (1) BR112015014145B1 (ru)
CA (1) CA2892899C (ru)
CL (1) CL2015001781A1 (ru)
EA (1) EA038333B1 (ru)
ES (1) ES2659953T3 (ru)
HK (1) HK1210954A1 (ru)
MX (1) MX2015008036A (ru)
MY (1) MY173280A (ru)
NZ (1) NZ708742A (ru)
PE (1) PE20151165A1 (ru)
PH (1) PH12015501428B1 (ru)
SA (1) SA515360628B1 (ru)
SG (1) SG11201504873RA (ru)
UA (1) UA117672C2 (ru)
WO (1) WO2014096300A2 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014096300A2 (en) 2012-12-21 2014-06-26 Janssen R&D Ireland Antibacterial compounds
US9801909B2 (en) 2015-04-06 2017-10-31 The Penn State Research Foundation Compositions and methods for combating bacterial infections by killing persister cells with mitomycin C

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE744970A (fr) * 1969-01-28 1970-07-27 Lilly Co Eli Agents antiviraux et immuno-depresseurs
US4028374A (en) 1975-11-03 1977-06-07 Morton-Norwich Products, Inc. Antibacterial thiocyanatobenzothiazoles
GB8816519D0 (en) 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
GB9107341D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
CA2362705A1 (en) * 1999-03-19 2000-09-28 Joseph B. Santella, Iii N-adamant-1-yl-n'-¬4-chlorobenzothiazol-2-yl| urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
BRPI0312927B8 (pt) 2002-07-25 2021-05-25 Janssen Pharmaceutica Nv "compostos, derivados de quinolina, composição, seu uso como inibidores micobacteriais, bem como processo para preparação dos referidos derivados".
CA2527174C (en) 2003-05-30 2014-03-25 F.Hoffmann-La Roche Ag Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine a2a receptor
EP1670804A2 (en) 2003-09-10 2006-06-21 GPC Biotech AG Heterobicyclic compounds as pharmaceutically active agents
US20050130974A1 (en) * 2003-10-17 2005-06-16 Rigel Pharmaceuticals, Inc. Benzothiazole compositions and their use as ubiquitin ligase inhibitors
WO2007140439A2 (en) 2006-05-31 2007-12-06 Abbott Laboratories Compounds as cannabinoid receptor ligands and uses thereof
GB0724342D0 (en) 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
WO2014096300A2 (en) 2012-12-21 2014-06-26 Janssen R&D Ireland Antibacterial compounds

Also Published As

Publication number Publication date
SA515360628B1 (ar) 2017-05-18
EP2934498A2 (en) 2015-10-28
BR112015014145B1 (pt) 2020-12-29
NZ708742A (en) 2020-06-26
US20150344449A1 (en) 2015-12-03
MX2015008036A (es) 2015-10-29
CN104981238A (zh) 2015-10-14
WO2014096300A2 (en) 2014-06-26
CL2015001781A1 (es) 2015-11-06
CA2892899C (en) 2021-07-20
SG11201504873RA (en) 2015-07-30
US20170369457A1 (en) 2017-12-28
CN104981238B (zh) 2019-05-31
JP6441229B2 (ja) 2018-12-19
AU2013366572B2 (en) 2018-08-30
EA038333B1 (ru) 2021-08-11
MY173280A (en) 2020-01-10
KR20150099772A (ko) 2015-09-01
AU2013366572A1 (en) 2015-06-04
WO2014096300A3 (en) 2014-08-14
JP2016503776A (ja) 2016-02-08
KR102233199B1 (ko) 2021-03-30
UA117672C2 (uk) 2018-09-10
US9951032B2 (en) 2018-04-24
AP2015008503A0 (en) 2015-06-30
PE20151165A1 (es) 2015-08-19
US9758497B2 (en) 2017-09-12
EP2934498B1 (en) 2017-11-15
BR112015014145A2 (pt) 2017-07-11
US9428474B2 (en) 2016-08-30
HK1210954A1 (en) 2016-05-13
ES2659953T3 (es) 2018-03-20
CA2892899A1 (en) 2014-06-26
US20160347728A1 (en) 2016-12-01
PH12015501428A1 (en) 2015-09-07
PH12015501428B1 (en) 2015-09-07

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