MX339227B - Alimentacion alcalina. - Google Patents
Alimentacion alcalina.Info
- Publication number
- MX339227B MX339227B MX2013002144A MX2013002144A MX339227B MX 339227 B MX339227 B MX 339227B MX 2013002144 A MX2013002144 A MX 2013002144A MX 2013002144 A MX2013002144 A MX 2013002144A MX 339227 B MX339227 B MX 339227B
- Authority
- MX
- Mexico
- Prior art keywords
- polypeptide
- cultivating
- cell
- producing
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a un método para cultivar una célula bacteriana que comprende la adición de un aminoácido en solución alcalina utilizado para regulación de pH. También un aspecto es un método para producir un polipéptido que comprende las etapas de: a) proporcionar una célula bacteriana que comprende un ácido nucleico que codifica para el polipéptido, b) cultivar la célula proporcionada, c) ajustar el valor de pH durante el cultivo con una solución básica que comprende un aminoácido, d) recuperar el polipéptido de la célula para el medio de cultivo y de esta manera producir el polipéptido.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10008997 | 2010-08-30 | ||
PCT/EP2011/064598 WO2012028522A1 (en) | 2010-08-30 | 2011-08-25 | Alkaline feed |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013002144A MX2013002144A (es) | 2013-04-03 |
MX339227B true MX339227B (es) | 2016-05-17 |
Family
ID=43088050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013002144A MX339227B (es) | 2010-08-30 | 2011-08-25 | Alimentacion alcalina. |
Country Status (12)
Country | Link |
---|---|
US (2) | US8951756B2 (es) |
EP (1) | EP2611900B1 (es) |
JP (2) | JP5798193B2 (es) |
KR (1) | KR101584414B1 (es) |
CN (1) | CN103068967B (es) |
BR (1) | BR112013004396A2 (es) |
CA (1) | CA2807428A1 (es) |
ES (1) | ES2558751T3 (es) |
HK (1) | HK1181811A1 (es) |
MX (1) | MX339227B (es) |
RU (1) | RU2631001C2 (es) |
WO (1) | WO2012028522A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012028522A1 (en) * | 2010-08-30 | 2012-03-08 | F. Hoffmann-La Roche Ag | Alkaline feed |
KR20140054115A (ko) | 2011-08-25 | 2014-05-08 | 에프. 호프만-라 로슈 아게 | 단축 테트라넥틴-아포지단백질 a-i 융합 단백질, 그를 함유하는 지질 입자 및 그의 용도 |
BR112014004463A2 (pt) | 2011-08-25 | 2017-03-28 | Hoffmann La Roche | método de cromatografia de troca de cátion e de ânion |
BR112014017141A2 (pt) * | 2012-01-19 | 2019-09-24 | Univ Cincinnati | método de tratamento de diabetes usando-se apolipoproteína a-iv não glicosilada |
PL2959006T3 (pl) | 2013-02-22 | 2018-11-30 | F.Hoffmann-La Roche Ag | Zastosowanie szczepu prokariotycznego z usuniętą auksotrofią aminokwasową do produkcji rekombinacyjnej polipeptydu |
EP3184547A1 (en) | 2015-10-29 | 2017-06-28 | F. Hoffmann-La Roche AG | Anti-tpbg antibodies and methods of use |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60118196A (ja) * | 1983-11-30 | 1985-06-25 | Takeda Chem Ind Ltd | インタ−フェロンの製造法 |
DD295867A5 (de) | 1988-07-28 | 1991-11-14 | Zi F. Mikrobiologie U. Exper. Therapie, | Verfahren zur steuerung des wachstums von aerob-submersen mikroorganismen-kulturen |
DE4001518A1 (de) | 1990-01-19 | 1991-07-25 | Biotechnolog Forschung Gmbh | Verfahren zur hochzelldichte-fermentation von escherichia coli in einem ruehrkesselfermentor |
SE9203753D0 (sv) * | 1992-12-11 | 1992-12-11 | Kabi Pharmacia Ab | Expression system for producing apolipoprotein ai-m |
AR005035A1 (es) | 1995-12-11 | 1999-04-07 | Merck Patent Ges Mit Beschränkter Haftung | Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas. |
GB9602825D0 (en) | 1996-02-12 | 1996-04-10 | Therexsys Ltd | Method of plasmid dna production and purification |
US6291245B1 (en) * | 1998-07-15 | 2001-09-18 | Roche Diagnostics Gmbh | Host-vector system |
CN1268641C (zh) | 2000-11-10 | 2006-08-09 | 普罗蒂奥制药公司 | 载脂蛋白类似物 |
EP1451335A1 (en) * | 2001-12-05 | 2004-09-01 | DSM IP Assets B.V. | Process for the production of an aromatic amino acid metabolite or derivative thereof |
CA2443365C (en) | 2002-11-19 | 2010-01-12 | F. Hoffmann-La Roche Ag | Methods for the recombinant production of antifusogenic peptides |
WO2012028522A1 (en) * | 2010-08-30 | 2012-03-08 | F. Hoffmann-La Roche Ag | Alkaline feed |
-
2011
- 2011-08-25 WO PCT/EP2011/064598 patent/WO2012028522A1/en active Application Filing
- 2011-08-25 RU RU2013112563A patent/RU2631001C2/ru not_active IP Right Cessation
- 2011-08-25 MX MX2013002144A patent/MX339227B/es active IP Right Grant
- 2011-08-25 KR KR1020137007871A patent/KR101584414B1/ko not_active IP Right Cessation
- 2011-08-25 US US13/217,540 patent/US8951756B2/en not_active Expired - Fee Related
- 2011-08-25 JP JP2013526412A patent/JP5798193B2/ja not_active Expired - Fee Related
- 2011-08-25 BR BR112013004396A patent/BR112013004396A2/pt not_active IP Right Cessation
- 2011-08-25 CN CN201180041407.3A patent/CN103068967B/zh not_active Expired - Fee Related
- 2011-08-25 EP EP11748406.3A patent/EP2611900B1/en not_active Not-in-force
- 2011-08-25 ES ES11748406.3T patent/ES2558751T3/es active Active
- 2011-08-25 CA CA2807428A patent/CA2807428A1/en not_active Abandoned
-
2013
- 2013-08-02 HK HK13109024.6A patent/HK1181811A1/zh not_active IP Right Cessation
-
2015
- 2015-01-28 US US14/607,932 patent/US9845347B2/en not_active Expired - Fee Related
- 2015-07-10 JP JP2015139021A patent/JP2016005461A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20130100301A (ko) | 2013-09-10 |
RU2013112563A (ru) | 2014-10-10 |
RU2631001C2 (ru) | 2017-09-15 |
MX2013002144A (es) | 2013-04-03 |
HK1181811A1 (zh) | 2013-11-15 |
CN103068967A (zh) | 2013-04-24 |
WO2012028522A1 (en) | 2012-03-08 |
EP2611900A1 (en) | 2013-07-10 |
EP2611900B1 (en) | 2015-11-25 |
ES2558751T3 (es) | 2016-02-08 |
US20150132802A1 (en) | 2015-05-14 |
JP5798193B2 (ja) | 2015-10-21 |
JP2013537432A (ja) | 2013-10-03 |
US8951756B2 (en) | 2015-02-10 |
CA2807428A1 (en) | 2012-03-08 |
US9845347B2 (en) | 2017-12-19 |
BR112013004396A2 (pt) | 2016-05-17 |
KR101584414B1 (ko) | 2016-01-13 |
CN103068967B (zh) | 2016-05-04 |
JP2016005461A (ja) | 2016-01-14 |
US20130323783A1 (en) | 2013-12-05 |
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Legal Events
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FG | Grant or registration |