MX337468B - Anticuerpos anti notch-1. - Google Patents

Anticuerpos anti notch-1.

Info

Publication number
MX337468B
MX337468B MX2011013717A MX2011013717A MX337468B MX 337468 B MX337468 B MX 337468B MX 2011013717 A MX2011013717 A MX 2011013717A MX 2011013717 A MX2011013717 A MX 2011013717A MX 337468 B MX337468 B MX 337468B
Authority
MX
Mexico
Prior art keywords
epitope
antibodies
notch1
nrr
domain
Prior art date
Application number
MX2011013717A
Other languages
English (en)
Spanish (es)
Other versions
MX2011013717A (es
Inventor
Zdenek Hostomsky
Kang Li
John Andrew Lippincott
Qinghai Peng
Donna Marie Stone
Ping Wei
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42575817&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX337468(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of MX2011013717A publication Critical patent/MX2011013717A/es
Publication of MX337468B publication Critical patent/MX337468B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2011013717A 2009-06-18 2010-06-16 Anticuerpos anti notch-1. MX337468B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21819309P 2009-06-18 2009-06-18
PCT/IB2010/052711 WO2010146550A1 (en) 2009-06-18 2010-06-16 Anti notch-1 antibodies

Publications (2)

Publication Number Publication Date
MX2011013717A MX2011013717A (es) 2012-05-29
MX337468B true MX337468B (es) 2016-03-02

Family

ID=42575817

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011013717A MX337468B (es) 2009-06-18 2010-06-16 Anticuerpos anti notch-1.

Country Status (18)

Country Link
US (1) US9090690B2 (enExample)
EP (2) EP3431501A1 (enExample)
JP (2) JP6059985B2 (enExample)
KR (1) KR101570898B1 (enExample)
CN (1) CN102686610A (enExample)
AU (1) AU2010261364B2 (enExample)
BR (1) BRPI1011805A2 (enExample)
CA (1) CA2765989C (enExample)
CO (1) CO6480924A2 (enExample)
IL (1) IL217066A0 (enExample)
MX (1) MX337468B (enExample)
NZ (1) NZ597611A (enExample)
PE (1) PE20121494A1 (enExample)
PH (1) PH12011502609B1 (enExample)
RU (1) RU2011151287A (enExample)
SG (1) SG176731A1 (enExample)
WO (1) WO2010146550A1 (enExample)
ZA (1) ZA201109282B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2334331B1 (en) * 2008-10-01 2015-04-29 F. Hoffmann-La Roche AG Anti-notch2 antibodies and methods of use
NZ597611A (en) 2009-06-18 2014-03-28 Pfizer Anti notch-1 antibodies
JP6025563B2 (ja) * 2009-09-30 2016-11-16 ジェネンテック， インコーポレイテッド Ｎｏｔｃｈ３アンタゴニストを用いたＮｏｔｃｈ１アンタゴニスト耐性癌の治療
WO2012080891A1 (en) * 2010-12-15 2012-06-21 Rinat Neuroscience Corp. Anti-notch-1 antibodies
KR101580726B1 (ko) 2010-12-15 2015-12-29 와이어쓰 엘엘씨 항-노치1 항체
RU2015116480A (ru) 2012-11-07 2016-12-27 Пфайзер Инк. Анти-notch3 антитела и конъюганты антител с лекарственным средством
CN106659778A (zh) * 2014-03-07 2017-05-10 昂考梅德药品有限公司 用Notch1抗体治疗癌症的方法
RU2017103289A (ru) 2014-07-11 2018-08-14 Дженентек, Инк. Ингибирование пути notch
US11026996B2 (en) * 2016-05-25 2021-06-08 The Trustees Of Columbia University In The City Of New York Human Notch1 based fusion proteins as decoy inhibitors of jagged-notch signaling and DLL-notch signaling
WO2018081648A2 (en) * 2016-10-29 2018-05-03 Genentech, Inc. Anti-mic antibidies and methods of use
CN112703200B (zh) 2018-08-31 2025-01-10 布鲁姆科技株式会社 针对糖化终产物的抗体及其应用
JPWO2024053742A1 (enExample) 2022-09-09 2024-03-14

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Also Published As

Publication number Publication date
EP3431501A1 (en) 2019-01-23
CA2765989A1 (en) 2010-12-23
IL217066A0 (en) 2012-02-29
JP6059985B2 (ja) 2017-01-11
CN102686610A (zh) 2012-09-19
KR20120071379A (ko) 2012-07-02
PE20121494A1 (es) 2012-11-01
PH12011502609B1 (en) 2018-11-07
US20120093813A1 (en) 2012-04-19
WO2010146550A1 (en) 2010-12-23
NZ597611A (en) 2014-03-28
ZA201109282B (en) 2012-08-29
RU2011151287A (ru) 2013-07-27
MX2011013717A (es) 2012-05-29
AU2010261364A1 (en) 2012-01-19
EP2443151A1 (en) 2012-04-25
JP2012530487A (ja) 2012-12-06
SG176731A1 (en) 2012-01-30
CO6480924A2 (es) 2012-07-16
PH12011502609A1 (en) 2012-11-12
BRPI1011805A2 (pt) 2016-10-11
CA2765989C (en) 2016-11-29
AU2010261364B2 (en) 2015-05-07
KR101570898B1 (ko) 2015-11-23
JP2016121162A (ja) 2016-07-07
US9090690B2 (en) 2015-07-28

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