MX337138B - Construcciones oralmente disponibles a base de lípidos. - Google Patents

Construcciones oralmente disponibles a base de lípidos.

Info

Publication number
MX337138B
MX337138B MX2010003396A MX2010003396A MX337138B MX 337138 B MX337138 B MX 337138B MX 2010003396 A MX2010003396 A MX 2010003396A MX 2010003396 A MX2010003396 A MX 2010003396A MX 337138 B MX337138 B MX 337138B
Authority
MX
Mexico
Prior art keywords
orally bioavailable
based constructs
diagnostic agent
lipid
composition
Prior art date
Application number
MX2010003396A
Other languages
English (en)
Other versions
MX2010003396A (es
Inventor
John R Lau
Walter B Geho
Original Assignee
Sdg Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sdg Inc filed Critical Sdg Inc
Publication of MX2010003396A publication Critical patent/MX2010003396A/es
Publication of MX337138B publication Critical patent/MX337138B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inorganic Chemistry (AREA)

Abstract

La presente invención se refiere a una composición capaz de acompañar un agente terapéutico o diagnóstico obtenible típicamente por vía oral a través del entorno del tracto digestivo, de tal manera que el agente terapéutico o diagnóstico es biodisponible; la composición puede ser o no direccionada a receptores celulares específicos, tales como hepatocitos; los agentes terapéuticos incluyen, pero no se limitan a las mismas, insulina, calcitonina, serotonina y otras proteínas; se efectúa el direccionamiento con agentes de direccionamiento a base de biotina o metales.
MX2010003396A 2007-09-28 2008-09-26 Construcciones oralmente disponibles a base de lípidos. MX337138B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/904,937 US8962015B2 (en) 2007-09-28 2007-09-28 Orally bioavailable lipid-based constructs
PCT/US2008/077990 WO2009042945A1 (en) 2007-09-28 2008-09-26 Orally bioavailable lipid-based constructs

Publications (2)

Publication Number Publication Date
MX2010003396A MX2010003396A (es) 2010-11-12
MX337138B true MX337138B (es) 2016-02-02

Family

ID=40508640

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010003396A MX337138B (es) 2007-09-28 2008-09-26 Construcciones oralmente disponibles a base de lípidos.

Country Status (19)

Country Link
US (3) US8962015B2 (es)
EP (2) EP2205217B1 (es)
JP (2) JP2010540559A (es)
KR (2) KR20160005130A (es)
CN (2) CN104666246A (es)
AU (3) AU2008304269B2 (es)
BR (1) BRPI0817478A2 (es)
CA (1) CA2704712C (es)
DK (1) DK2205217T3 (es)
ES (1) ES2661325T3 (es)
HK (1) HK1211205A1 (es)
HU (1) HUE037002T2 (es)
LT (1) LT2205217T (es)
MX (1) MX337138B (es)
NO (1) NO2205217T3 (es)
PL (1) PL2205217T3 (es)
PT (1) PT2205217T (es)
WO (1) WO2009042945A1 (es)
ZA (1) ZA201002177B (es)

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JP6143679B2 (ja) * 2011-02-07 2017-06-07 ライフ テクノロジーズ コーポレーション 感受性化合物を安定化するための組成物および方法
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KR102019911B1 (ko) 2011-11-02 2019-09-09 키바이오사이언스 아게 질병 및 장애 치료용 펩타이드 유사체
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US11077173B2 (en) 2017-03-13 2021-08-03 Sdg, Inc. Lipid-based nanoparticles and methods using same
KR20190124269A (ko) * 2017-03-13 2019-11-04 에스디지,인코포레이티드 안정성이 증진된 지질 기반 나노입자
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
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GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
JP2023553362A (ja) * 2020-11-27 2023-12-21 ディーアンドディー ファーマテック インコーポレイテッド ビオチン部分、脂肪酸部分またはその組合せを連結されて有する生物学的活性材料結合体
CN116940384A (zh) * 2020-11-27 2023-10-24 D&D制药技术股份有限公司 具有与生物素部分、脂肪酸部分或其组合偶联的生物活性材料缀合物的口服制剂

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US10568835B2 (en) 2020-02-25
CN101917971A (zh) 2010-12-15
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HK1211205A1 (en) 2016-05-20
EP2205217A1 (en) 2010-07-14
LT2205217T (lt) 2018-03-26
EP3360540A1 (en) 2018-08-15
HUE037002T2 (hu) 2018-08-28
KR101747433B1 (ko) 2017-06-14
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MX2010003396A (es) 2010-11-12
EP2205217A4 (en) 2013-01-23
EP2205217B1 (en) 2017-12-13
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CN104666246A (zh) 2015-06-03
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US11517529B2 (en) 2022-12-06
US20150125518A1 (en) 2015-05-07
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US20200405638A1 (en) 2020-12-31
AU2008304269B2 (en) 2015-07-09
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US8962015B2 (en) 2015-02-24
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