MX2023004593A - Inhibidores de tirosina cinasa 2 (tyk2) y usos de los mismos. - Google Patents
Inhibidores de tirosina cinasa 2 (tyk2) y usos de los mismos.Info
- Publication number
- MX2023004593A MX2023004593A MX2023004593A MX2023004593A MX2023004593A MX 2023004593 A MX2023004593 A MX 2023004593A MX 2023004593 A MX2023004593 A MX 2023004593A MX 2023004593 A MX2023004593 A MX 2023004593A MX 2023004593 A MX2023004593 A MX 2023004593A
- Authority
- MX
- Mexico
- Prior art keywords
- tyk2
- tyk2 inhibitors
- inhibitors
- inhibition
- compositions
- Prior art date
Links
- 229940123371 Tyrosine kinase 2 inhibitor Drugs 0.000 title 1
- 101000844245 Homo sapiens Non-receptor tyrosine-protein kinase TYK2 Proteins 0.000 abstract 2
- 102100032028 Non-receptor tyrosine-protein kinase TYK2 Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
La presente invención proporciona compuestos, composiciones de los mismos, y métodos de uso de los mismos para la inhibición de TYK2, y el tratamiento de trastornos mediados por TYK2.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762538536P | 2017-07-28 | 2017-07-28 | |
US201762560615P | 2017-09-19 | 2017-09-19 | |
US201862664048P | 2018-04-27 | 2018-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023004593A true MX2023004593A (es) | 2023-05-08 |
Family
ID=65040855
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020001103A MX2020001103A (es) | 2017-07-28 | 2018-07-26 | Inhibidores de tirosina cinasa 2 (tyk2) y usos de los mismos. |
MX2023004593A MX2023004593A (es) | 2017-07-28 | 2020-01-28 | Inhibidores de tirosina cinasa 2 (tyk2) y usos de los mismos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020001103A MX2020001103A (es) | 2017-07-28 | 2018-07-26 | Inhibidores de tirosina cinasa 2 (tyk2) y usos de los mismos. |
Country Status (12)
Country | Link |
---|---|
US (8) | US11046698B2 (es) |
EP (1) | EP3658557A4 (es) |
JP (2) | JP7216705B2 (es) |
KR (1) | KR20200035293A (es) |
CN (3) | CN111194317A (es) |
AU (2) | AU2018306444B2 (es) |
BR (1) | BR112020001714A2 (es) |
CA (1) | CA3070621A1 (es) |
IL (1) | IL271999A (es) |
MX (2) | MX2020001103A (es) |
SG (1) | SG11202000714QA (es) |
WO (1) | WO2019023468A1 (es) |
Families Citing this family (23)
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US20160251376A1 (en) | 2015-02-27 | 2016-09-01 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
EP4327809A3 (en) | 2015-09-02 | 2024-04-17 | Takeda Pharmaceutical Company Limited | Tyk2 inhibitors and uses thereof |
WO2018010789A1 (en) | 2016-07-13 | 2018-01-18 | Humabs Biomed Sa | Novel antibodies specifically binding to zika virus epitopes and uses thereof |
AU2017345736B2 (en) | 2016-10-21 | 2022-04-07 | Takeda Pharmaceutical Company Limited | TYK2 inhibitors and uses thereof |
CA3090842A1 (en) | 2018-03-12 | 2019-09-19 | Abbvie Inc. | Inhibitors of tyrosine kinase 2 mediated signaling |
EP3849981B1 (en) * | 2018-09-10 | 2023-02-01 | Eli Lilly and Company | Pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives useful in the treatment of psoriasis and systemic lupus erythematosus |
AU2019360941A1 (en) | 2018-10-15 | 2021-04-29 | Takeda Pharmaceutical Company Limited | TYK2 inhibitors and uses thereof |
MX2021004769A (es) | 2018-10-30 | 2021-08-24 | Kronos Bio Inc | Compuestos, composiciones, y metodos para modular la actividad cdk9. |
AU2020218267A1 (en) * | 2019-02-07 | 2021-09-30 | Ventyx Biosciences, Inc. | TYK2 pseudokinase ligands |
JP2022529311A (ja) | 2019-03-26 | 2022-06-21 | ベンティックス バイオサイエンシーズ,インク. | Tyk2偽キナーゼリガンド |
WO2021092246A1 (en) * | 2019-11-08 | 2021-05-14 | Ventyx Biosciences, Inc. | Tyk2 pseudokinase ligands |
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CN115052660B (zh) * | 2020-02-12 | 2024-01-09 | 伊莱利利公司 | 取代的7-(甲氨基)吡唑并[1,5-a]嘧啶-3-甲酰胺衍生物 |
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-
2018
- 2018-07-26 WO PCT/US2018/043917 patent/WO2019023468A1/en active Application Filing
- 2018-07-26 SG SG11202000714QA patent/SG11202000714QA/en unknown
- 2018-07-26 MX MX2020001103A patent/MX2020001103A/es unknown
- 2018-07-26 EP EP18837151.2A patent/EP3658557A4/en active Pending
- 2018-07-26 AU AU2018306444A patent/AU2018306444B2/en active Active
- 2018-07-26 BR BR112020001714-0A patent/BR112020001714A2/pt active Search and Examination
- 2018-07-26 CA CA3070621A patent/CA3070621A1/en active Pending
- 2018-07-26 CN CN201880057821.5A patent/CN111194317A/zh active Pending
- 2018-07-26 US US16/046,481 patent/US11046698B2/en active Active
- 2018-07-26 CN CN202311776307.6A patent/CN117946115A/zh active Pending
- 2018-07-26 CN CN202311772622.1A patent/CN117946114A/zh active Pending
- 2018-07-26 JP JP2020504110A patent/JP7216705B2/ja active Active
- 2018-07-26 KR KR1020207005884A patent/KR20200035293A/ko not_active Application Discontinuation
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2019
- 2019-04-12 US US16/382,734 patent/US10508120B2/en active Active
- 2019-04-12 US US16/382,869 patent/US10562907B2/en active Active
- 2019-04-12 US US16/382,824 patent/US10562906B2/en active Active
- 2019-04-12 US US16/382,680 patent/US10577373B2/en active Active
- 2019-04-12 US US16/382,907 patent/US10570145B2/en active Active
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2020
- 2020-01-13 IL IL271999A patent/IL271999A/en unknown
- 2020-01-28 MX MX2023004593A patent/MX2023004593A/es unknown
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2021
- 2021-03-23 US US17/210,066 patent/US20220356184A1/en active Pending
- 2021-09-14 US US17/447,648 patent/US20230056447A1/en not_active Abandoned
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2022
- 2022-11-28 AU AU2022279375A patent/AU2022279375A1/en active Pending
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2023
- 2023-01-20 JP JP2023007066A patent/JP2023052540A/ja active Pending
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