MX2022004000A - Uso de un anticuerpo de muerte anti-programada 1 (anti-pd-1) en combinacion con una quimioterapia doble a base de platino (pt-dc) para el tratamiento de cancer de pulmon. - Google Patents

Uso de un anticuerpo de muerte anti-programada 1 (anti-pd-1) en combinacion con una quimioterapia doble a base de platino (pt-dc) para el tratamiento de cancer de pulmon.

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Publication number
MX2022004000A
MX2022004000A MX2022004000A MX2022004000A MX2022004000A MX 2022004000 A MX2022004000 A MX 2022004000A MX 2022004000 A MX2022004000 A MX 2022004000A MX 2022004000 A MX2022004000 A MX 2022004000A MX 2022004000 A MX2022004000 A MX 2022004000A
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Mexico
Prior art keywords
antibody
cancer
cancer agent
lung cancer
treatment
Prior art date
Application number
MX2022004000A
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English (en)
Inventor
David Feltquate
Allen C Chen
Original Assignee
Bristol Myers Squibb Co
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Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX2022004000A publication Critical patent/MX2022004000A/es

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    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
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Abstract

La presente invención se refiere a un método para tratar un sujeto afligido con un cáncer de pulmón, en el cual el método comprende administrar al sujeto cantidades terapéuticamente efectivas de: (a) un agente anti-cancerígeno el cual es un anticuerpo o una porción del mismo de unión al antígeno que se une específicamente a un receptor de Muerte Programada 1 (PD-1) e inhibe la actividad de PD-1; y (b) otro agente anti-cancerígeno. El otro agente anti-cancerígeno puede ser una quimioterapia doble a base de platino, un inhibidor de tirosina cinasa dirigido a EGFR, un anticuerpo anti-VEGF, un anticuerpo del Antígeno 4 del Linfocito T antiCitotóxico (CTLA-4), o cualquier otra terapia usada para tratar cáncer de pulmón en la técnica o descrito en la presente.
MX2022004000A 2014-05-15 2016-11-10 Uso de un anticuerpo de muerte anti-programada 1 (anti-pd-1) en combinacion con una quimioterapia doble a base de platino (pt-dc) para el tratamiento de cancer de pulmon. MX2022004000A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461993917P 2014-05-15 2014-05-15
US201462005640P 2014-05-30 2014-05-30
US201562152669P 2015-04-24 2015-04-24

Publications (1)

Publication Number Publication Date
MX2022004000A true MX2022004000A (es) 2022-04-26

Family

ID=53276304

Family Applications (2)

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MX2016014753A MX2016014753A (es) 2014-05-15 2015-05-15 Tratamiento de cancer de pulmon con el uso de una combinacion de un anticuerpo de muerte anti-programada 1 (anti-pd-1) y otro agente anti-cancerigeno.
MX2022004000A MX2022004000A (es) 2014-05-15 2016-11-10 Uso de un anticuerpo de muerte anti-programada 1 (anti-pd-1) en combinacion con una quimioterapia doble a base de platino (pt-dc) para el tratamiento de cancer de pulmon.

Family Applications Before (1)

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MX2016014753A MX2016014753A (es) 2014-05-15 2015-05-15 Tratamiento de cancer de pulmon con el uso de una combinacion de un anticuerpo de muerte anti-programada 1 (anti-pd-1) y otro agente anti-cancerigeno.

Country Status (10)

Country Link
US (3) US20170158776A1 (es)
EP (2) EP3760229A3 (es)
JP (1) JP2017515859A (es)
KR (2) KR20170003692A (es)
CN (2) CN115590953A (es)
BR (1) BR112016026559A8 (es)
CA (1) CA2949121A1 (es)
MX (2) MX2016014753A (es)
RU (1) RU2695332C2 (es)
WO (1) WO2015176033A1 (es)

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