MX2021001213A - Variantes de alfa-amilasas que tienen sustituciones de aminoácidos que bajan el pka del ácido general. - Google Patents

Variantes de alfa-amilasas que tienen sustituciones de aminoácidos que bajan el pka del ácido general.

Info

Publication number
MX2021001213A
MX2021001213A MX2021001213A MX2021001213A MX2021001213A MX 2021001213 A MX2021001213 A MX 2021001213A MX 2021001213 A MX2021001213 A MX 2021001213A MX 2021001213 A MX2021001213 A MX 2021001213A MX 2021001213 A MX2021001213 A MX 2021001213A
Authority
MX
Mexico
Prior art keywords
amylases
pka
amino acid
variant alpha
acid substitutions
Prior art date
Application number
MX2021001213A
Other languages
English (en)
Inventor
Jonathan K Lassila
Patricia Tran
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of MX2021001213A publication Critical patent/MX2021001213A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001Alpha-amylase (3.2.1.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Abstract

Se describen composiciones y métodos que se refieren a enzimas de variantes de a-amilasa. Las variantes de a-amilasa son útiles, por ejemplo, para la licuefacción y sacarificación del almidón, limpieza de manchas de almidón, desaprestado de productos textiles, repostería y elaboración de cerveza.
MX2021001213A 2018-07-31 2019-07-30 Variantes de alfa-amilasas que tienen sustituciones de aminoácidos que bajan el pka del ácido general. MX2021001213A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862712446P 2018-07-31 2018-07-31
PCT/US2019/044254 WO2020028443A1 (en) 2018-07-31 2019-07-30 Variant alpha-amylases having amino acid substitutions that lower the pka of the general acid

Publications (1)

Publication Number Publication Date
MX2021001213A true MX2021001213A (es) 2021-08-24

Family

ID=67734801

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021001213A MX2021001213A (es) 2018-07-31 2019-07-30 Variantes de alfa-amilasas que tienen sustituciones de aminoácidos que bajan el pka del ácido general.

Country Status (7)

Country Link
US (1) US20230174962A1 (es)
EP (1) EP3830231A1 (es)
JP (1) JP2021532795A (es)
CN (1) CN112805361A (es)
CA (1) CA3108284A1 (es)
MX (1) MX2021001213A (es)
WO (1) WO2020028443A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

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