MX2021000685A - Novedosa variante de proteina exportadora de l-triptofano y procedimiento para producir l-triptofano utilizando el mismo. - Google Patents
Novedosa variante de proteina exportadora de l-triptofano y procedimiento para producir l-triptofano utilizando el mismo.Info
- Publication number
- MX2021000685A MX2021000685A MX2021000685A MX2021000685A MX2021000685A MX 2021000685 A MX2021000685 A MX 2021000685A MX 2021000685 A MX2021000685 A MX 2021000685A MX 2021000685 A MX2021000685 A MX 2021000685A MX 2021000685 A MX2021000685 A MX 2021000685A
- Authority
- MX
- Mexico
- Prior art keywords
- tryptophan
- producing
- protein variant
- novel
- same
- Prior art date
Links
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229960004799 tryptophan Drugs 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 2
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020190040397A KR102205717B1 (ko) | 2019-04-05 | 2019-04-05 | 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법 |
| PCT/KR2020/003855 WO2020204427A1 (ko) | 2019-04-05 | 2020-03-20 | 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021000685A true MX2021000685A (es) | 2021-03-25 |
Family
ID=72666413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021000685A MX2021000685A (es) | 2019-04-05 | 2020-03-20 | Novedosa variante de proteina exportadora de l-triptofano y procedimiento para producir l-triptofano utilizando el mismo. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11524981B2 (enExample) |
| EP (1) | EP3789398A4 (enExample) |
| JP (2) | JP7539871B2 (enExample) |
| KR (1) | KR102205717B1 (enExample) |
| CN (1) | CN112823165B (enExample) |
| BR (1) | BR112021000765B1 (enExample) |
| CA (1) | CA3105666C (enExample) |
| MX (1) | MX2021000685A (enExample) |
| RU (1) | RU2763603C1 (enExample) |
| WO (1) | WO2020204427A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102647745B1 (ko) * | 2020-05-27 | 2024-03-14 | 씨제이제일제당 주식회사 | 신규 l-타이로신 배출 단백질 변이체 및 이를 이용한 l-타이로신을 생산하는 방법 |
| KR102617168B1 (ko) * | 2020-12-09 | 2023-12-21 | 씨제이제일제당 (주) | 쉬와넬라 오네이덴시스 유래 단백질을 발현하는 미생물, 및 이를 이용한 l-아미노산 생산 방법 |
| KR102284728B1 (ko) * | 2021-01-25 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 H(+)/Cl(-) 익스체인지 트랜스포터 변이체 및 이를 이용한 L-트립토판 생산 방법 |
| KR102284726B1 (ko) * | 2021-01-25 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 타우토머레이즈 pptA 변이체 및 이를 이용한 L-트립토판 생산 방법 |
| KR102284725B1 (ko) * | 2021-01-25 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 페로체라테이즈 변이체 및 이를 이용한 l-트립토판 생산 방법 |
| KR102284727B1 (ko) * | 2021-01-25 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 단백질 HtrL 변이체 및 이를 이용한 L-트립토판 생산 방법 |
| KR102284729B1 (ko) * | 2021-01-29 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 시아네이트 트랜스포터 패밀리 단백질변이체 및 이를 이용한 l-트립토판 생산 방법 |
| KR102688095B1 (ko) * | 2021-04-28 | 2024-07-24 | 씨제이제일제당 주식회사 | 변이형 SpoT 단백질 및 이를 이용한 L-아미노산을 생산하는 방법 |
| WO2024090885A1 (ko) * | 2022-10-24 | 2024-05-02 | 대상 주식회사 | Dna-결합 전사 제어인자 malt 신규 변이체 및 이를 이용한 l-방향족 아미노산의 생산 방법 |
| KR20240110477A (ko) * | 2022-10-24 | 2024-07-15 | 대상 주식회사 | 신규 단백질 변이체 및 이를 이용한 l-방향족 아미노산의 생산 방법 |
| EP4610350A1 (en) * | 2022-10-24 | 2025-09-03 | Daesang Corporation | Novel phenylalanine:h+ symporter phep variant, and method for producing l-aromatic amino acids using same |
| KR102877975B1 (ko) * | 2022-12-28 | 2025-10-31 | 씨제이제일제당 주식회사 | 외래 글루타민 신테타제가 도입된 미생물 및 이를 이용한 l-트립토판의 생산 방법 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19548222A1 (de) | 1995-12-22 | 1997-06-26 | Forschungszentrum Juelich Gmbh | Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern |
| RU2148642C1 (ru) * | 1998-12-23 | 2000-05-10 | ЗАО "Научно-исследовательский институт АДЖИНОМОТО-Генетика" (ЗАО "АГРИ") | Фрагмент днк rhtc, кодирующий синтез белка rhtc, придающего повышенную устойчивость к l-треонину бактериям escherichia coli, и способ получения l-аминокислоты |
| RU2175351C2 (ru) | 1998-12-30 | 2001-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот |
| PL207852B1 (pl) * | 2001-11-23 | 2011-02-28 | Ajinomoto Co Inc | Bakteria z rodzaju Escherichia wytwarzająca L-aminokwas, sposób wytwarzania L-fenyloalaniny lub L-tryptofanu i sposób wytwarzania niższych estrów alkilowych α-L-aspartylo-L-fenyloalaniny |
| KR101142885B1 (ko) * | 2003-12-15 | 2012-05-10 | 씨제이제일제당 (주) | 트립토판 생합성 관련 변이유전자를 함유한 대장균 변이주및 이를 이용한 트립토판 제조방법 |
| DE102004037572A1 (de) * | 2004-08-03 | 2006-02-23 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| WO2007026958A1 (ja) | 2005-09-01 | 2007-03-08 | Suntory Limited | トリプトファントランスポーター遺伝子及びその用途 |
| CN101273138A (zh) * | 2005-09-27 | 2008-09-24 | 味之素株式会社 | 产生l-氨基酸的细菌和用于产生l-氨基酸的方法 |
| EP1979486B1 (en) * | 2006-01-30 | 2013-04-17 | Ajinomoto Co., Inc. | L-amino acid producing bacterium and method of producing l-amino acid |
| JP2009165355A (ja) * | 2006-04-28 | 2009-07-30 | Ajinomoto Co Inc | Ｌ−アミノ酸を生産する微生物及びｌ−アミノ酸の製造法 |
| DE102006032634A1 (de) * | 2006-07-13 | 2008-01-17 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren |
| MY173848A (en) | 2012-01-10 | 2020-02-24 | Cj Cheiljedang Corp | A microorganism of the genus escherichia having enhanced l-tryptophan productivity and a method for producing l-tryptophan using the same |
| JP6841428B2 (ja) * | 2015-06-10 | 2021-03-10 | 公立大学法人 富山県立大学 | 活性型変異酵素の製造方法および新規活性型変異酵素、並びに可溶性化変異タンパク質の製造方法 |
| WO2018116555A1 (ja) * | 2016-12-22 | 2018-06-28 | 昭和電工株式会社 | 接着剤、これを用いた積層体、電池外装材、並びに電池ケース及びその製造方法 |
| KR102035844B1 (ko) * | 2018-02-23 | 2019-10-23 | 씨제이제일제당 주식회사 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
| KR101968317B1 (ko) * | 2018-02-23 | 2019-04-11 | 씨제이제일제당 주식회사 | 신규 l-트립토판 배출 단백질 및 이를 이용한 l-트립토판을 생산하는 방법 |
-
2019
- 2019-04-05 KR KR1020190040397A patent/KR102205717B1/ko active Active
-
2020
- 2020-03-20 BR BR112021000765-2A patent/BR112021000765B1/pt active IP Right Grant
- 2020-03-20 WO PCT/KR2020/003855 patent/WO2020204427A1/ko not_active Ceased
- 2020-03-20 JP JP2021517540A patent/JP7539871B2/ja active Active
- 2020-03-20 RU RU2020139396A patent/RU2763603C1/ru active
- 2020-03-20 CN CN202080004146.7A patent/CN112823165B/zh active Active
- 2020-03-20 EP EP20784578.5A patent/EP3789398A4/en active Pending
- 2020-03-20 MX MX2021000685A patent/MX2021000685A/es unknown
- 2020-03-20 CA CA3105666A patent/CA3105666C/en active Active
- 2020-03-20 US US17/268,691 patent/US11524981B2/en active Active
-
2022
- 2022-09-29 JP JP2022155934A patent/JP2022185040A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR102205717B1 (ko) | 2021-01-22 |
| EP3789398A1 (en) | 2021-03-10 |
| CA3105666A1 (en) | 2020-10-08 |
| JP2022185040A (ja) | 2022-12-13 |
| EP3789398A4 (en) | 2021-08-25 |
| JP2021525108A (ja) | 2021-09-24 |
| BR112021000765A2 (pt) | 2021-04-13 |
| US11524981B2 (en) | 2022-12-13 |
| KR20200118334A (ko) | 2020-10-15 |
| CN112823165A (zh) | 2021-05-18 |
| CA3105666C (en) | 2023-06-27 |
| BR112021000765B1 (pt) | 2022-05-10 |
| WO2020204427A1 (ko) | 2020-10-08 |
| JP7539871B2 (ja) | 2024-08-26 |
| RU2763603C1 (ru) | 2021-12-30 |
| CN112823165B (zh) | 2024-03-26 |
| US20220009973A1 (en) | 2022-01-13 |
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