MX2020007924A - Novedoso exportador de l-triptofano y procedimiento de produccion de l-triptofano mediante el uso del mismo. - Google Patents

Novedoso exportador de l-triptofano y procedimiento de produccion de l-triptofano mediante el uso del mismo.

Info

Publication number
MX2020007924A
MX2020007924A MX2020007924A MX2020007924A MX2020007924A MX 2020007924 A MX2020007924 A MX 2020007924A MX 2020007924 A MX2020007924 A MX 2020007924A MX 2020007924 A MX2020007924 A MX 2020007924A MX 2020007924 A MX2020007924 A MX 2020007924A
Authority
MX
Mexico
Prior art keywords
tryptophan
producing
novel
same
export protein
Prior art date
Application number
MX2020007924A
Other languages
English (en)
Inventor
Hyo Jin Kim
Hyun Ah Kim
Chang Il Seo
Ki Yong Cheong
Moo Young Jung
Tae Yeon Kim
Sung Kwang Son
Hye Ryun Yoo
Jae Min Lee
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2020007924A publication Critical patent/MX2020007924A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente divulgación se refiere a un microorganismo productor de L-triptofano en el que el microorganismo esta modificado de tal manera que se expresa una proteína que tiene una actividad de exportación de L-triptofano que comprende la secuencia de aminoácidos de la SEQ ID NO: 1, y un procedimiento de producción de L-triptofano mediante el uso del microorganismo. [Figura 1].
MX2020007924A 2018-02-23 2019-02-22 Novedoso exportador de l-triptofano y procedimiento de produccion de l-triptofano mediante el uso del mismo. MX2020007924A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180022054A KR101968317B1 (ko) 2018-02-23 2018-02-23 신규 l-트립토판 배출 단백질 및 이를 이용한 l-트립토판을 생산하는 방법
PCT/KR2019/002238 WO2019164348A1 (ko) 2018-02-23 2019-02-22 신규 l-트립토판 배출 단백질 및 이를 이용한 l-트립토판을 생산하는 방법

Publications (1)

Publication Number Publication Date
MX2020007924A true MX2020007924A (es) 2020-09-18

Family

ID=66167275

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020007924A MX2020007924A (es) 2018-02-23 2019-02-22 Novedoso exportador de l-triptofano y procedimiento de produccion de l-triptofano mediante el uso del mismo.

Country Status (13)

Country Link
US (1) US10995378B2 (es)
EP (1) EP3561061B1 (es)
JP (1) JP7098731B2 (es)
KR (1) KR101968317B1 (es)
CN (1) CN110418843B (es)
BR (1) BR112020014626B1 (es)
CA (1) CA3091331C (es)
DK (1) DK3561061T3 (es)
ES (1) ES2883824T3 (es)
HU (1) HUE055339T2 (es)
MX (1) MX2020007924A (es)
RU (1) RU2761871C1 (es)
WO (1) WO2019164348A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102205717B1 (ko) * 2019-04-05 2021-01-22 씨제이제일제당 주식회사 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법
KR102251948B1 (ko) * 2019-10-31 2021-05-17 대상 주식회사 mdfA 유전자 불활성 및 yicL 유전자 도입에 의해 방향족 아미노산 생산능력이 향상된 균주
KR102278000B1 (ko) * 2020-03-17 2021-07-15 씨제이제일제당 주식회사 프리페네이트 디하이드라타아제 활성 강화를 통한 l-트립토판을 생산하는 방법
KR102647745B1 (ko) * 2020-05-27 2024-03-14 씨제이제일제당 주식회사 신규 l-타이로신 배출 단백질 변이체 및 이를 이용한 l-타이로신을 생산하는 방법
KR20220092182A (ko) 2020-12-24 2022-07-01 씨제이제일제당 (주) L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법
KR20220147981A (ko) 2021-04-28 2022-11-04 씨제이제일제당 (주) 변이형 SpoT 단백질 및 이를 이용한 L-아미노산을 생산하는 방법
KR20240000168A (ko) * 2022-06-23 2024-01-02 씨제이제일제당 (주) L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법
KR20240000169A (ko) * 2022-06-23 2024-01-02 씨제이제일제당 (주) L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548222A1 (de) * 1995-12-22 1997-06-26 Forschungszentrum Juelich Gmbh Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern
RU2148642C1 (ru) * 1998-12-23 2000-05-10 ЗАО "Научно-исследовательский институт АДЖИНОМОТО-Генетика" (ЗАО "АГРИ") Фрагмент днк rhtc, кодирующий синтез белка rhtc, придающего повышенную устойчивость к l-треонину бактериям escherichia coli, и способ получения l-аминокислоты
RU2175351C2 (ru) * 1998-12-30 2001-10-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот
DE19907347A1 (de) * 1999-02-20 2000-08-24 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
TR200607443T2 (tr) 1999-06-25 2007-10-22 Basf Aktiengesellschaft Membran sentezi ve membran nakli dahilinde corynebacterium glutamicum kodlayan proteinler
RU2229513C2 (ru) * 2001-11-23 2004-05-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты)
CA2468179C (en) * 2001-11-23 2013-05-21 Ajinomoto Co., Inc. Method for producing l-amino acids using bacteria belonging to the genus escherichia
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
DE102005020538A1 (de) * 2005-05-03 2006-11-23 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
KR101632642B1 (ko) 2015-01-29 2016-06-22 씨제이제일제당 주식회사 신규한 프로모터 및 그의 용도
KR101704198B1 (ko) * 2015-05-14 2017-02-08 씨제이제일제당 (주) L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법
CN110283823B (zh) 2016-08-31 2023-05-12 Cj第一制糖株式会社 新型启动子及其应用

Also Published As

Publication number Publication date
CN110418843A (zh) 2019-11-05
HUE055339T2 (hu) 2021-11-29
JP2021509808A (ja) 2021-04-08
US10995378B2 (en) 2021-05-04
CA3091331A1 (en) 2019-08-29
DK3561061T3 (da) 2021-08-16
ES2883824T3 (es) 2021-12-09
BR112020014626A2 (pt) 2020-12-08
US20200063219A1 (en) 2020-02-27
CN110418843B (zh) 2021-04-20
RU2761871C1 (ru) 2021-12-13
EP3561061A4 (en) 2020-02-26
EP3561061A1 (en) 2019-10-30
WO2019164348A1 (ko) 2019-08-29
EP3561061B1 (en) 2021-06-09
BR112020014626B1 (pt) 2021-11-16
KR101968317B1 (ko) 2019-04-11
CA3091331C (en) 2023-01-24
JP7098731B2 (ja) 2022-07-11

Similar Documents

Publication Publication Date Title
MX2020007924A (es) Novedoso exportador de l-triptofano y procedimiento de produccion de l-triptofano mediante el uso del mismo.
MX2021000685A (es) Novedosa variante de proteina exportadora de l-triptofano y procedimiento para producir l-triptofano utilizando el mismo.
MY191029A (en) Novel polypeptide and method of producing imp using the same
PH12020550529A1 (en) Recombinant bacterium capable of producing l-lysine, construction method thereof and production method of l-lysine
MX2023009109A (es) Una variante de isopropilmalato sintasa novedosa y un procedimiento de produccion de l-leucina usando la misma.
MX2019011778A (es) Composicion para producir tagatosa y procedimiento de produccion de tagatosa usando la misma.
MX2021014853A (es) Variante de proteina de exportacion de l-treonina y procedimiento para la produccion de l-treonina mediante el uso de la misma.
MY195408A (en) Novel Aspartokinase Variant and Method for Producing L- Amino Acid Using the Same
SG10201806655TA (en) Microorganism producing o-acetyl-homoserine and method for producing o-acetylhomoserine using the same
MX2020007591A (es) Homoserina deshidrogenasa modificada y procedimiento de produccion de homoserina o l-aminoacido derivado de homoserina mediante el uso de la misma.
MX2021004704A (es) Variante proteica receptora de ampc y procedimiento de produccion de l-aminoacido mediante el uso de la misma.
MY172080A (en) Microorganisms having putrescine productivity and process for producing putrescine using the same
MX2021004610A (es) Variante proteica receptora de ampc y procedimiento de produccion de l-aminoacido mediante el uso de la misma.
PH12020550976A1 (en) Camp receptor protein variant and method of producing l-amino acid using the same
PH12020551948A1 (en) Monospecific and multispecific anti-tmeff2 antibodies and their uses
MY177465A (en) A microorganism of the genus escherichia producing l-tryptophan and a method for producing l-tryptophan using the same
MY184725A (en) Process for the purification of biomass hydrolysate
MX2016002651A (es) Microorganismo modificado para la produccion mejorada de alanina.
MX2019011730A (es) Composicion para producir tagatosa y procedimiento de produccion de tagatosa usando la misma.
MX2019008241A (es) Un enlazador polipeptídico para preparar anticuerpos multispecíficos.
ZA202205485B (en) L-methionine producing microorganism to which protein encoded by foreign metz gene is introduced and method for producing l-methionine using same
MY175834A (en) A microorganism of the genus escherichia producing l-tryptophan and method for producing l-tryptophan using the same
MY172369A (en) Microorganism of the genus escherichia producing l-tryptophan and method for producing l-tryptophan using the same
MX2021012296A (es) Microorganismo que produce l-aminoacido y procedimiento de produccion de l-aminoacido mediante el uso del mismo.
MY189749A (en) A microorganism of the genus corynebacterium producing l-lysine and a method for producing l-lysine using the same