MX2020007628A - Composiciones y metodos de uso. - Google Patents
Composiciones y metodos de uso.Info
- Publication number
- MX2020007628A MX2020007628A MX2020007628A MX2020007628A MX2020007628A MX 2020007628 A MX2020007628 A MX 2020007628A MX 2020007628 A MX2020007628 A MX 2020007628A MX 2020007628 A MX2020007628 A MX 2020007628A MX 2020007628 A MX2020007628 A MX 2020007628A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions
- same
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- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Abstract
La invención hace referencia a composiciones (por ejemplo, composiciones farmacéuticas) que incluyen, por ejemplo, proteínas de fusión Fc IL-22, métodos para confeccionarlas y métodos para utilizarlas, por ejemplo, para el tratamiento de enfermedades (por ejemplo, IBD).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862622704P | 2018-01-26 | 2018-01-26 | |
US201862697372P | 2018-07-12 | 2018-07-12 | |
PCT/US2019/015268 WO2019148020A1 (en) | 2018-01-26 | 2019-01-25 | Compositions and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020007628A true MX2020007628A (es) | 2020-10-12 |
Family
ID=65409540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020007628A MX2020007628A (es) | 2018-01-26 | 2019-01-25 | Composiciones y metodos de uso. |
Country Status (20)
Country | Link |
---|---|
US (1) | US20200353049A1 (es) |
EP (1) | EP3743088B1 (es) |
JP (1) | JP7345479B2 (es) |
KR (1) | KR20200125590A (es) |
CN (1) | CN112020365A (es) |
AU (1) | AU2019212703A1 (es) |
BR (1) | BR112020015016A2 (es) |
CA (1) | CA3088763A1 (es) |
DK (1) | DK3743088T3 (es) |
ES (1) | ES2932861T3 (es) |
HR (1) | HRP20221448T1 (es) |
HU (1) | HUE060435T2 (es) |
IL (1) | IL276135A (es) |
LT (1) | LT3743088T (es) |
MX (1) | MX2020007628A (es) |
PL (1) | PL3743088T3 (es) |
PT (1) | PT3743088T (es) |
RS (1) | RS63812B1 (es) |
SI (1) | SI3743088T1 (es) |
WO (1) | WO2019148020A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104623637A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | Il-22二聚体在制备静脉注射药物中的应用 |
CN109328069B (zh) | 2016-04-15 | 2023-09-01 | 亿一生物医药开发(上海)有限公司 | Il-22在治疗坏死性小肠结肠炎中的用途 |
TW202118793A (zh) * | 2019-07-26 | 2021-05-16 | 美商建南德克公司 | 以 IL-22 Fc 融合蛋白預防或治療移植物抗宿主疾病 (GVHD) 之投藥 |
WO2021164744A1 (en) * | 2020-02-19 | 2021-08-26 | Evive Biotechnology (Shanghai) Ltd | Methods for treating graft versus host disease |
WO2021207662A1 (en) | 2020-04-10 | 2021-10-14 | Genentech, Inc. | Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome |
WO2022191550A1 (ko) * | 2021-03-09 | 2022-09-15 | (주)지아이이노베이션 | IgE Fc 수용체의 알파 서브유닛의 세포외 도메인을 포함하는 융합단백질의 제형 |
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CA2906101A1 (en) | 2013-03-15 | 2014-09-18 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
TR201809571T4 (tr) | 2013-03-15 | 2018-07-23 | Hoffmann La Roche | Ll-22 polipeptidleri ile ıl-22 fc füzyon proteinleri ve kullanım yöntemleri. |
US10646569B2 (en) * | 2017-05-16 | 2020-05-12 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
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2019
- 2019-01-25 PT PT197049661T patent/PT3743088T/pt unknown
- 2019-01-25 DK DK19704966.1T patent/DK3743088T3/da active
- 2019-01-25 MX MX2020007628A patent/MX2020007628A/es unknown
- 2019-01-25 EP EP19704966.1A patent/EP3743088B1/en active Active
- 2019-01-25 WO PCT/US2019/015268 patent/WO2019148020A1/en unknown
- 2019-01-25 JP JP2020540787A patent/JP7345479B2/ja active Active
- 2019-01-25 HR HRP20221448TT patent/HRP20221448T1/hr unknown
- 2019-01-25 ES ES19704966T patent/ES2932861T3/es active Active
- 2019-01-25 BR BR112020015016-9A patent/BR112020015016A2/pt unknown
- 2019-01-25 KR KR1020207021787A patent/KR20200125590A/ko not_active Application Discontinuation
- 2019-01-25 LT LTEPPCT/US2019/015268T patent/LT3743088T/lt unknown
- 2019-01-25 PL PL19704966.1T patent/PL3743088T3/pl unknown
- 2019-01-25 AU AU2019212703A patent/AU2019212703A1/en active Pending
- 2019-01-25 CA CA3088763A patent/CA3088763A1/en active Pending
- 2019-01-25 HU HUE19704966A patent/HUE060435T2/hu unknown
- 2019-01-25 CN CN201980022499.7A patent/CN112020365A/zh active Pending
- 2019-01-25 RS RS20221131A patent/RS63812B1/sr unknown
- 2019-01-25 SI SI201930399T patent/SI3743088T1/sl unknown
-
2020
- 2020-07-19 IL IL276135A patent/IL276135A/en unknown
- 2020-07-24 US US16/938,777 patent/US20200353049A1/en active Pending
Also Published As
Publication number | Publication date |
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LT3743088T (lt) | 2022-12-27 |
BR112020015016A2 (pt) | 2020-12-29 |
CA3088763A1 (en) | 2019-08-01 |
EP3743088B1 (en) | 2022-10-12 |
JP7345479B2 (ja) | 2023-09-15 |
CN112020365A (zh) | 2020-12-01 |
AU2019212703A1 (en) | 2020-08-13 |
WO2019148020A1 (en) | 2019-08-01 |
ES2932861T3 (es) | 2023-01-27 |
KR20200125590A (ko) | 2020-11-04 |
HRP20221448T1 (hr) | 2023-01-20 |
EP3743088A1 (en) | 2020-12-02 |
JP2021511362A (ja) | 2021-05-06 |
PL3743088T3 (pl) | 2023-03-20 |
DK3743088T3 (da) | 2022-12-19 |
SI3743088T1 (sl) | 2023-01-31 |
US20200353049A1 (en) | 2020-11-12 |
TW201938794A (zh) | 2019-10-01 |
RS63812B1 (sr) | 2023-01-31 |
HUE060435T2 (hu) | 2023-03-28 |
IL276135A (en) | 2020-09-30 |
PT3743088T (pt) | 2022-12-05 |
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