MX2020003742A - Variantes del factor estimulador de colonias de granulocitos de porcino y sus usos. - Google Patents

Variantes del factor estimulador de colonias de granulocitos de porcino y sus usos.

Info

Publication number
MX2020003742A
MX2020003742A MX2020003742A MX2020003742A MX2020003742A MX 2020003742 A MX2020003742 A MX 2020003742A MX 2020003742 A MX2020003742 A MX 2020003742A MX 2020003742 A MX2020003742 A MX 2020003742A MX 2020003742 A MX2020003742 A MX 2020003742A
Authority
MX
Mexico
Prior art keywords
porcine
csf
variants
csf variants
pigs
Prior art date
Application number
MX2020003742A
Other languages
English (en)
Inventor
Peter Connor Canning
Nickolas Knudsen
Md Harunur Rashid
Original Assignee
Elanco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco Us Inc filed Critical Elanco Us Inc
Publication of MX2020003742A publication Critical patent/MX2020003742A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a variantes del factor estimulador de colonias de granulocitos de porcino (pG-CSF); las variantes del pG-CSF son útiles en el tratamiento para prevenir o reducir la incidencia de infecciones bacterianas en cerdos; se describen también métodos de tratamiento de los cerdos.
MX2020003742A 2017-10-11 2018-10-10 Variantes del factor estimulador de colonias de granulocitos de porcino y sus usos. MX2020003742A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762570877P 2017-10-11 2017-10-11
PCT/US2018/055203 WO2019075053A1 (en) 2017-10-11 2018-10-10 PORCINE G-CSF VARIANTS AND USES THEREOF

Publications (1)

Publication Number Publication Date
MX2020003742A true MX2020003742A (es) 2020-10-28

Family

ID=66101096

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020003742A MX2020003742A (es) 2017-10-11 2018-10-10 Variantes del factor estimulador de colonias de granulocitos de porcino y sus usos.

Country Status (13)

Country Link
US (2) US11578111B2 (es)
EP (1) EP3694535A4 (es)
JP (1) JP7046173B2 (es)
KR (2) KR102461760B1 (es)
CN (1) CN111565736B (es)
AR (1) AR113756A1 (es)
AU (2) AU2018348138A1 (es)
BR (1) BR112020007037A2 (es)
CA (1) CA3077215A1 (es)
MX (1) MX2020003742A (es)
RU (1) RU2020113060A (es)
TW (1) TWI820046B (es)
WO (1) WO2019075053A1 (es)

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CA2452540A1 (en) * 1996-10-15 1998-04-23 Amgen Inc. Keratinocyte growth factor-2 products
JP2004511201A (ja) * 1998-10-09 2004-04-15 カイロン コーポレイション ナイセリアゲノム配列およびそれらの使用方法
JP2002540065A (ja) 1999-01-29 2002-11-26 アムジェン インコーポレーテッド Gcsfコンジュゲート
US7323174B1 (en) * 2000-06-12 2008-01-29 Arizona Board Of Regents On Behalf Of The University Of Arizona Modulation of immune response and methods based thereon
MXPA04000068A (es) * 2001-06-22 2005-06-06 Pharmacia Corp Conjugados de progenipoyetina modificados quimicamente.
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BR0213402A (pt) * 2001-10-29 2004-10-13 Crucell Holland Bv Métodos para identificar uma célula de mamìfero capaz de produzir uma molécula proteinácea, para selecionar uma célula de mamìfero capaz de produzir uma molécula proteinácea, para se obter uma célula de mamìfero a partir de uma população heterogênea de células, e para produzir uma molécula proteinácea, composição farmaceuticamente aceitável, eritropoietina recombinantemente produzida, usos de uma célula de mamìfero, da eritropoietina recombinantemente produzida, e de uma composição de moléculas semelhantes à eritropoietina, preparação farmacêutica, método para o tratamento preventivo e/ou terapêutico de um distúrbio, composição de moléculas semelhates à eritropoietina, métodos para produzir, em uma célula de mamìfero, moléculas proteináceas, para produzir uma fração enriquecida em uma molécula proteinácea, e para fracionar uma mistura que contém moléculas proteináceas, fração, e, usos de uma fração ou composição, e de eritropoietina recombinantemente produzìvel em uma célula de mamìfero
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Also Published As

Publication number Publication date
JP2020536935A (ja) 2020-12-17
AR113756A1 (es) 2020-06-10
AU2018348138A1 (en) 2020-04-23
AU2021204727B2 (en) 2023-02-09
CA3077215A1 (en) 2019-04-18
US20230340051A1 (en) 2023-10-26
US20210054039A1 (en) 2021-02-25
CN111565736A (zh) 2020-08-21
WO2019075053A1 (en) 2019-04-18
EP3694535A1 (en) 2020-08-19
TW201928058A (zh) 2019-07-16
KR102461760B1 (ko) 2022-10-31
KR20220150432A (ko) 2022-11-10
AU2021204727A1 (en) 2021-08-05
RU2020113060A (ru) 2021-11-12
JP7046173B2 (ja) 2022-04-01
TWI820046B (zh) 2023-11-01
CN111565736B (zh) 2024-03-08
BR112020007037A2 (pt) 2020-11-17
US11578111B2 (en) 2023-02-14
KR20200066628A (ko) 2020-06-10
RU2020113060A3 (es) 2021-12-27
KR102619071B1 (ko) 2023-12-27
EP3694535A4 (en) 2021-07-28

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